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Biomedical subjects

G Caroli

Publications and source records attributed to G Caroli.

At least 37 records · Page 2Linked to original sources
PubMed1977

[Presence and etio-epidemiological significance of halophilic vibriones in various material].

In this work data of isolation of halophilic vibrios from coastal water of central Tyrrhenian sea are reported, and the epidemiological significance of such strains is discussed. V. Parahaemolyticus was identified in 8 out of 20 samples of sea water. V. alginolyticus was identified in 8 out of 26 samples of fishes and mussels examined and in 8 out of 20 sea water samples. Halophilic vibrios had not been isolated from 12 samples of sewage water and from 27 healthy or pathological human stool samples. From 6 different samples (sewage water and human stools included) bacteriophages active against V. parahaemolyticus were isolated. This study demonstrates that in our geographical area V. parahaemolyticus is present. The pathogenicity of such strains cannot be demonstrated because of the lack of available experimental models in vitro and/or in vivo. It is also impossible to assume their etiological rôle in human pathology, due to the absence of specific epidemics or single cases in our country.

Animals↗
PubMed1976

[Salmonella strains recently widespread in Italy and its sensitivity to some common antibiotics (author's transl)].

A study has been carried out in order to evaluate the sensitivity of a group of some 517 strains of salmonella identified by the Pathogenic Enterobacteria Centre of Central Italy in the biennium 1974-75 to various antibiotics and chemotherapeutic agents. As far as the average percentage of sensitivity to the drugs by the strains tested is concerned, the results obtained are indicative of a situation which may be optimistically looked upon as far as our regions are concerned. Some widely used drugs such as chloramphenicol, ampicillin, streptomycin and kanamycin showed a high percentage of activity in vitro towards Salmonellae with the exception of S. wien, whereas gentamicin, co-trimoxazole, nalidixic acid, furoxone and cephradine were more widely active, No substantial differences were found between strains normally present in our regions which are, at present, characterized by a stationary epidemiological situation (S. typhi, S. paratyphi B, S. enteritidis, S. typhi-murium) and sertypes which, having been present in Italy for a long time, appear today to have an increasing diffusion (S. infantis, S. newport, S blockley and S. thompson). As for the Salmonellae of recent appearance and diffusion in Italy (S. panama, S. agona, S. wien) a more resistant pattern of behaviour to various drugs was found; this was particularly remarkable for S. wien which is the last in order of appearance in our population. Finally, the probable reasons for this difference in behaviour are discussed in view of our present knowledge on drug-resistance and on the role played by antibiotics as selective agents at an environmental level.

Animals↗
PubMed1973

WHO cooperative studies on the phage-typing of mycobacteria. 1. Phage lysis of Czechoslovak and Italian strains of Mycobacterium tuberculosis.

Although phage-typing of some pathogenic microbes-e.g., Escherichia coli and the genera Salmonella, Staphylococcus, and Streptomyces-is in routine use, little progress has yet been made in the phage-typing of mycobacteria, chiefly because mycobacteriophages possess a polyvalence that prevents the reliable identification of individual species of mycobacterium. Furthermore, laboratories cannot compare their results because they employ different methods and culture media and also because the phages used cannot be accurately identified. It has been shown that internationally reproducible results can be obtained for M. tuberculosis by selecting suitable mycobacteriophages and sensitive culture media, and by using a standardized technique of phage-typing. Under these conditions, phage lysis may be utilized to classify strains of M. tuberculosis.

Bacteriophage Typing↗