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Biomedical subjects

G C Sutton

Publications and source records attributed to G C Sutton.

At least 109 records · Page 6Linked to original sources
PubMed1971

Comparison of streptokinase and heparin in treatment of isolated acute massive pulmonary embolism.

Massive pulmonary embolism was confirmed by pulmonary arteriography in 23 patients. All were seen between 2 and 48 hours after the onset of embolism and none had pre-existing cardiorespiratory disease. Fifteen were treated with streptokinase and eight with heparin. Factors which might influence prognosis and rate of resolution were similar in the patients in each group, and there was no significant difference between the groups in terms of pretreatment haemodynamic or arteriographic findings. Haemodynamic and arteriographic findings after treatment for 72 hours provided an objective measurement of resolution, which was significantly greater in the streptokinase-treated patients. There was no mortality in either group, but treatment had to be changed in two heparin-treated patients because of clinical deterioration. The principal complication of treatment, seen more often in the streptokinase-treated patients, was bleeding from cut-down or operation sites.

Acute Disease↗
PubMed1970

A case of fatal peri-partum cardiomyopathy.

A case of fatal cardiomyopathy presenting in the puerperium is described. Despite extensive investigation and post-mortem examination no aetiological factor was found. The diagnosis of specific peri-partum cardiomyopathy is discussed.

Adult↗
PubMed1970

Major detachment of aortic prosthetic valves.

The clinical and investigatory findings in five instances of major detachment of an aortic valve prosthesis in four patients are described. This situation was associated with auscultatory and peripheral signs of aortic regurgitation and, in addition, a mid-diastolic murmur in the mitral area. From the haemodynamic and operative findings it was postulated that, in addition to severe aortic regurgitation, disturbance of mitral valve function occurred both in systole and diastole caused by the pivoting of the prosthesis attached to the base of the aortic leaflet of the mitral valve. Cardiac fluoroscopy confirmed the diagnosis.

Aortic Valve Insufficiency↗
PubMed1970

Acute massive pulmonary embolism. Clinical and haemodynamic findings in 23 patients studied by cardiac catheterization and pulmonary arteriography.

Twenty-three patients are reported in whom a diagnosis of acute massive pulmonary embolism was confirmed by pulmonary arteriography. All patients had a history of less than 48 hours' duration and only two had previous cardiorespiratory disease. In such patients the haemodynamic abnormalities determined at catheterization are due to pulmonary embolism as an isolated disturbance. These abnormalities include an only moderate degree of pulmonary hypertension (PA systolic pressure 38.4+/-6.8 mm. Hg), right ventricular ;failure' (RVED 11.5+/-4.9 mm. Hg), arterial oxygen desaturation (86.4+/-11.2%) and a wide arteriovenous oxygen difference (8.1+/-1.8 ml./100 ml.), and low cardiac output. These haemodynamic abnormalities find their expression in the presentation and the clinical, electrocardiographic, and radiological findings which are described.

Acute Disease↗