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Biomedical subjects

G C Descovich

Publications and source records attributed to G C Descovich.

At least 37 records · Page 2Linked to original sources

[The Brisighella study. I. Non-metabolic risk factors].

The Brisighella Study, an epidemiological observational investigation on coronary heart disease risk factors was performed in a little Emilia-Romagna town with agricultural background. At entry, in 1972, 1,491 males and 1,448 females were enrolled from the residents of the inner part of the town. The participation response was very high (93%). In this paper the smoking habits and physical activity are reported. The prevalence of smoking habits was 51.8% in males, quiet different from the female group (24.5%). Heavy smokers were more frequently observed in young people, than in the oldest female groups. The physical activity mean levels were very low both in males and in females and the prevalence of heavy physical activity during leisure time was very low, especially in the woman.

Adolescent↗

[The Brisighella study. II. Metabolic risk factors].

The Epidemiological Study of Brisighella, a rural little town of Emilia-Romagna, started in 1972. At entry 1448 females and 1491 males, aged 14-84 years, were examined. In this paper the mean values of Total Serum Cholesterol (TC), Triglycerides (TC), Serum Uric Acid (SUA) and Fasting Blood Sugar (FBS) for age classes and sex, were described. This values were for all males, of 222.6 mg/dl (TC), 153.0 mg/dl (TG), 53.5 mg/dl (SUA) and 85.0 mg/dl (FBS). In the females the mean TC values were higher than in the males (226.2 mg/dl); the mean values of other parameters were lower: 129.1 mg/dl (TG), 83.3 mg/dl (FBS) and 47.0 mg/l (SUA).

Adolescent↗

[The Brisighella study. III. Hypertension as a risk factor (author's transl)].

The Brisighella Study was performed in a little Emilia-Romagna town with agricultural background to observe coronary heart disease risk factors in this population. At entry, 1972, 1491 males and 1448 females were controlled from the residents of the inner part of the town. The participation response was very high (93%). In this study the hypertension evaluation as risk factor is reported. Measurement of blood pressure has been made in according to W.H.O. criteria. Blood pressure mean values, hypertension prevalence, borderline blood pressure prevalence and hypertension control level have been recorded. The male subjects with hypertension were 33.53%, while female subjects were 33.77%. Borderline blood pressure was higher in males than in females (32.0% vs. 25.7%). Hypertension control level in the examined sample was quite low, however, it appears higher than other reported in similar studies.

Adolescent↗

Multicentre study of soybean protein diet for outpatient hyper-cholesterolaemic patients.

The animal proteins in a low-lipid, low-cholesterol diet were substituted with a textured soybean preparation for 127 outpatients with stable type II hyperlipoproteinaemia selected from eight Italian and one Swiss lipid clinics. Eight weeks of the modified diet reduced plasma cholesterol by 23.1% in the 67 participating male patients and by 25.3% in the 60 females. No significant changes in plasma triglycerides, high-density lipoprotein cholesterol, and body weight were recorded. Better reductions in plasma cholesterol occurred in non-familial cases and in very young male patients. The acceptable taste of the soybean preparation used in this study, and its easy handling, indicate that this type of dietary treatment may be suitable for outpatients.

Adult↗

[Renal control of acid-base equilibrium during dyslipidemia].

Possible correlations between lipid metabolism and hydroelectrolytic and acid base balances were studied in pathological conditions. For this purpose 24 patients with essential dyslipidaemia without renal or hepatic disease, and 47 patients with varying disease conditions, 25 with profound alterations in the lipid balance, 22 with plasmatic lipid fractions completely normal, were studied. In cases of essential hyperlipidaemia, alongside the profound changes in the lipid complement, no significant alterations in plasma pH were observed; by contrast other cases frequently showed an upset acid base balance with or without changes in the lipid picture. Urinary determinations suggested different conclusions. The most important aspect was the observation in most cases of essential dyslipidaemia and in certain cases of secondary dyslipaemia, of paradoxical aciduria, namely aciduria of much greater extent than might have been expected on the basis of plasma pH value.

Acid-Base Equilibrium↗