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Biomedical subjects

G Bruno

Publications and source records attributed to G Bruno.

219 records · Page 13Linked to original sources

[The primary and secondary prevention of allergic diseases in the child "at risk" for atopy: a review of the literature and the authors' personal experience].

The increasing prevalence of the atopic diseases in the industrialized countries is closely linked together the numerous efforts to attempt to prevent them. Several Authors have suggested environmental and/or dietetic measures in the "at risk" babies in the first months of life, more critical for the atopy development. The environmental measures are directed to the avoidance of the major inhalant allergens (house dust mite, pet allergens, cigarette smoking, etc.). The employment of the acaricides can be useful to this purpose. The dietetic measures include: prolonged and exclusive breast feeding in the first six months of life, delayed and gradual weaning, avoidance of the major food allergens (cow's milk proteins, egg, fish, etc.) for the breast-feeding mother, choice of an adequate cow's milk substitute when the breast-feeding is not sufficient. For long time soya milk has been employed. In the last decade partially or highly hydrolyzed formulae were introduced, but in some cases they can be more allergenic of cow's milk. In this paper we reviewed the various environmental and dietetic measures and the different prevention programs that the several Authors have adopted in "at risk" babies.

Allergens↗

Is prevention of food allergy worthwhile?

Several studies performed in high-risk babies have demonstrated a significant reduction in the prevalence and severity of atopic diseases with dietary and environmental manipulations. It has been demonstrated that prolonged breast-feeding and the avoidance of cow's milk, eggs and fish during the first three months of lactation significantly decrease both the prevalence and the severity of atopic disease up to the age of 5 years. We have shown a significant reduction in both the prevalence and the incidence of atopic dermatitis, food allergy and asthma in high-risk children followed up to the age of 5 years who received preventive dietary (prolonged breast-feeding, cow's milk- and egg-free diet to the nursing mothers, supplementation with a soya formula containing sucrose when breast milk was not available, delayed weaning) and environmental measures (no smoking and no pets in the house, measures for the elimination of mites, etc.). However, occasionally, breast-fed infants may experience allergic sensitization to food antigens ingested by the mother during lactation. The factors that determine which infants will develop sensitization to food antigens in breast milk are not fully understood. The genetic predisposition to IgE-mediated hypersensitivity reactions is certainly a prerequisite; however, properties of human milk, such as immune characteristics, may play a role in the phenotypic expression of sensitization. Our studies suggest that the abnormally low levels of the long-chain polyunsaturated derivatives found in infants at risk of atopy are unlikely to be corrected by breast-feeding and may explain the contradictory results from studies on the effectiveness of breast milk against the development of atopic dermatitis.

Diet↗

[The laryngeal mask in pediatric anesthesia].

AIM. To evaluate the validity of general anesthesia using the laryngeal mask airway (LMA) in pediatrics in a series of 163 patients. MONITORING. ETCO2 and SpO2 were evaluated five minutes after the insertion of LMA and then at five minute intervals. SpO2 was evaluated every two minutes after the removal of LMA. Use of occasional arterial blood-gas analysis. EVALUATION OF QUALITY OF ANESTHESIA AND VENTILATION. Measurement of every complication during and after anesthesia. CONCLUSIONS. In pediatric anesthesia LMA represents a good link between anesthetic equipment and the patient.

Anesthesia, General↗