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Biomedical subjects

G Bruning

Publications and source records attributed to G Bruning.

2 recordsLinked to original sources

Effect of vasectomy on thyroid function.

Long-Evans rats vasectomized unilaterally or bilaterally at 2 months of age showed marked reductions in weight of testes, seminal vesicles and prostate glands 2 and 12 months post-vasectomy. Thyroid weight, thyroid 131I uptake, serum PB131I, circulating levels of serum T4 and chromatographic analysis of thyroid hydrolysates revealed no alterations due to vasectomy. These findings indicate that vasectomy, unilateral or bilateral, and whether of 2 or 12 months duration, did not exert an effect on thyroid function.

Animals↗

Sertoli cell nuclear changes in human testicular biopsies as revealed by three dimensional reconstruction.

Serial semithin sections of human testicular biopsy material were used for three-dimensional reconstruction in order to obtain information about Sertoli cell nuclei in normal and pathologically altered seminiferous epithelia. The three dimensional reconstruction program is based on the triangulation of image point series. It includes a calculation modus for determining surfaces and an approximation formula for the estimation of volumes. Nuclei from the following specimens were reconstructed and for each the volume (v), surface (s), and a quotient (v/s), which is regarded as a marker for the degree of membrane infoldings, were calculated as follows: (1) For normal spermatogenesis (stage 1, 2, 3, 5; n = 18) v = 409.7 +/- 33.0 microns 3, s = 429.6 +/- 40.5 microns 2, v/s = 0.96 +/- 0.05.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗