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Biomedical subjects

G Brunelli

Publications and source records attributed to G Brunelli.

97 records · Page 6Linked to original sources

Nerve suture.

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Humans↗

Electromicroscopic observations on small vessels in animals treated with sulfinpyrazone and placebo following vascular microsurgery.

To evaluate the antithrombotic effect of sulfinpyrazone on blood vessels (1-2 mm diameter) injured by microsurgical procedures, twenty male rabbits were chosen at random to receive sulfinpyrazone (10 mg/kg/die) or placebo three days prior to and on the morning of vascular microsurgery, which consisted of a complete transverse section, or a longitudinal section 1 cm long, of the femoral artery and vein, followed by interrupted suture. Scanning electron microscopy revealed consistently less fibrin and blood cell adhesion to the endothelial areas adjacent to the surgical trauma in the animals treated with sulfinpyrazone than in those treated with placebo. Our results agree with those reported in the literature, demonstrating the antithrombotic effects of sulfinpyrazone at the level of the vascular endothelium injured by various kinds of trauma and are sufficiently encouraging to justify testing this drug in the prevention of vascular thrombosis following microsurgical procedures in man.

Animals↗

Neurolysis and free microvascular omentum transfer in the treatment of postactinic palsies of the brachial plexus.

In this paper the results of treatment in 19 cases of postactinic paralysis of the brachial plexus are reported. The surgical technique aimed at resolving this condition, which is serious and often extremely painful, involves neurolysis and a long, narrow free omental graft and removal of the clavicle; the donor vessels are the left gastroepiploic arteries and veins; the recipient vessels are those distant from the irradiated area (often in the neck, transverse and facial arteries, veins affluent to the external jugular).

Brachial Plexus↗

Direct neurotization of severely damaged denervated muscles.

Previously, when part of a muscle and the terminal part of its nerve with its branches were removed through trauma, no technique for repair was available. A new technique for direct neurotization of denervated muscles is presented. This consists of the insertion of the distal stump of a nerve graft, divided into many small branches, directly into the muscle. Very good results were obtained in eight clinical cases of severely damaged muscles which were operated on according to this technique.

Humans↗