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Biomedical subjects

G Brill

Publications and source records attributed to G Brill.

31 records · Page 2Linked to original sources

[Magnetic resonance tomography in the differential diagnosis of pathologic changes in scrotal contents--a comparison with computed tomography].

48 patients with scrotal pathology were examined by magnetic resonance tomography (MRI) and computed tomography (CT). The diagnostic results were compared to surgical and histological findings. The correct diagnosis could be detected in 81% by CT and in 85% by MR. Another 27 patients were examined only by MR with positive results in 88%. Demonstration of tunica albuginea, imaging of testes in various planes and diagnostic accuracy in about 88% with missing ionising irradiation make MRI the most reliable diagnostic imaging in the classification of scrotal pathology. False negative results were found in 1/48 by CT and none by MRI. False positive results could be found in 2/75 of MRI examinations but none in CT.

Abscess↗

[Diagnosis of postpartum complications using CT and MRT].

Severe puerperal infections, iliacal and ovarian vein thrombosis are post-partum complications which are potentially life-threatening. They require prompt medical treatment. CT and MR enable diagnosis by noninvasive methods.

Female↗

The social supports of suicide attempters: the different roles of family and friends.

The social support patterns of a sample of 101 suicide attempters were compared with the patterns of a control sample on the basis of structured interview data. Network characteristics and the extent of support in different functional categories were examined as to their absolute and relative power to discriminate between the suicide attempters and the controls. A clear separation of the functions of kin and of friends/acquaintances emerged. The crucial difference between the attempters and the controls lay in the number of friends with whom the subjects had agreeable everyday interactions and in the number of kin that provided crisis support, both psychological and instrumental. Other support differences between the two groups were of secondary importance. While there was no overall difference in the frequency of social interactions between the two groups, the size of the social network differed greatly. Consequences for the conceptualization and measurement of social support as well as for the prevention of suicidal behavior are discussed.

Adult↗

[Pelvimetry using magnetic resonance tomography].

20 woman were examined before and after partum by means of conventional and magnetic resonance pelvimetry. Besides the usual data regarding the morphology and diameters of the pelvis, MRI gives information on the soft tissues of the birth canal without the added risk of irradiation to the mother and foetus. As shown by studies done in the USA it is also possible to determine foetal maturity by MRI; this will be done in the future.

Female↗

[Quantitative radiocardiography in the differential diagnosis and follow-up of cardiac disease (author's transl)].

Gated blood pool studies have been performed in about 400 patients, evaluating the regional motility and, by Fourier analysis, the following functional parameters: ejection fraction, peak ejection rate and its time, peak filling rate and its time. Wih the calibration procedure used during the first passage, we measured also the endsystolic and endiastolic volume of the left ventricle and the cardiac outpout. The changes of the different parameters caused by various diseases of the heart are discussed. It can be shown tha the measured values allow important conclusions to be made concerning the differential diagnosis. The examinations before and after surgery facilitate evaluation of therapeutic results.

Aortic Valve Insufficiency↗

Radioisotopic diagnosis and quantitation of left to right shunts in childhood and adolescence.

In 187 patients (141 adults and 46 children) left to right shunts were assessed using quantitative radionuclide angiography. After injection of 99mTc into the femoral vein time activity curves were registered over both lungs and the heart (Ohio Nuclear Camera, ON SIGMA 400, 110, HP 5407 computer). Using a modified gamma function area ratio technique the shunt sizes were calculated. The radioisotopic method allows a precise quantitation of left to right shunts ranging from 15--80%. There was a good agreement between the shunt sizes calculated by the radioisotopic method and oximetry or dye-dilution at cardiac catheterization (adults r = 0,87, children r = 0,85). The shunts sizes assessed with this nontraumatic method appear sufficiently reliable to be a real alternative to conventional techniques in screening for shunts.

Adolescent↗

[Determination of cardiac output and ejection fraction using radionuclide angiography. A comparsion with conventional diagnostic methods in cardiology (author's transl)].

Cardiac output and ejection fraction of left and right ventricle were determined in 75 patients with different heart diseases applying a newly developed method which combines radionuclide angiography and triggered blood pool scintigraphy. The comparison of cardiac output and ejection fraction as determined by dye-dilution or thermodilution technique and left ventricular angiography is excellent (coefficient of correlation r equal to 0.86 and r equal to 0.91). Cardiac output and ejection fraction can be determined with this method in single non-invasive operation, i.e. under physiological conditions. The ejection fractions can be determined with high statistical accuracy from time-activity curves of both ventricles. Similar to cine-angiography it is possible to evaluate the ventricular volume, the regional contraction patterns and aneurysmata. Outpatients can be investigated in 30 min. Since the radiation dose in comparison to cine-angiography is very low, this investigation can be repeated several times without harm to the patient. There are no risks as described for cardiac catheterization and contrast angiography. Patients with low cardiac output and ejection fraction can be classified as "high risk patients". In these patients cardiac catheterization can be avoided by applying the described method.

Cardiac Output↗

[Nuclear medical estimation of ejection fraction, cardiac output and time volume-differentials (author's transl)].

Gated blood pool investigation yield the ejection fraction as ratio of two volumes. To obtain absolut volumina (e.g. output volume in ml) the authors utilize the first transit of the tracer through the heart cava. Radionuclide output of the heart equals input during the first tracer passage, homogeneous infusion of the tracer provided. The resulting calibration factor makes possible the calculation of the stroke volume in the gated bloodpool procedure. Good correlation could be proven in 35 patients (r = 0.86 and 0.9, respectively).

Cardiac Output↗

[Diagnosis and quantiation of left to right shunts using radioisotopes].

After intravenous injection of 99mTcO-4 into the femoral vein the count-rate vs. time curve of a lung field is recorded and analysed (Ohio Nuclear Camera ON 110, pdp 11 computer GAMMA 11, hp 5407 computer). Using a modified gamma function area-ratio technique, the size of the left to right shunts is calculated and compared with cardiac catheter results (128 patients). The localisation of the left to right shunt (ASD or VSD) is possible, if the shunt size rises over 30%. The method may be an alternative to oximetry and conventional dilution techniques.

Adolescent↗