[Clinical study of sexual dysfunction after surgery of cancer of the rectum].
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Biomedical subjects
Publications and source records attributed to G Breda.
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The last 4 cases of our case series of renal cell carcinoma (RCC) with caval or cavo-atrial invasion were studied by ultrasonography (US), computerized tomography (CT scan), arteriography (AG) and venocavography (VC) (inferior and/or superior). A comparison is made with these different methods, with particular emphasis on (US). The authors' conclusions are that ultrasound may replace anterograde inferior cavography in the evaluation of thrombotic extension and, in addition, it seems to be capable of eliminating the false-positives or -negatives of this method. AG and VC are no longer necessary to determine the cavo-atrial extension of a tumor thrombus from RCC when US and CT scan are available and are correctly integrated.
The authors present the personal experience concerning with the use of the rigid ureteropyeloscopes. Two groups of patients have been studied. In the first one (14 subjects) the ureteropyeloscopy was performed either with diagnostic or therapeutic purposes, in the second one, just as upper urinary tract endoscopic control in patients previously submitted to distal ureteral resection and ureteroneocystostomy for urothelial neoplasia of the distal ureter. The authors presenting the personal results and complications, discuss the indications for the upper urinary tract endoscopy with rigid instruments.
They stress the need to evaluate certain characteristic of the tumour metastasis in the light of a series of limit events pin-pointing the lack of understanding of the natural history of renal carcinoma. They stress the need to evaluate certain characteristic of the tumour which are not normally taken into consideration by the surgeon: rate of proliferation, monitoring of hormonal receptors, and immunological monitoring. They reach the conclusion that treatment of renal carcinoma with metastasis must be the outcome of multidisciplinary planning.
The Authors report the results obtained administering 2.4 g/die of bacampicillin in a group of 30 patients suffering from both primary and secondary infections of the genito-urinary tracts. The antibiotic displayed excellent tolerability and therapeutic effectiveness, determining in almost all the treated cases either the resolution or, at least, significant improvement of the inflammatory course; only two patients, as a matter of fact, showed mild side effects.
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The authors offer a review of surgical procedures involving the left renal vein and including some major manipulation (disobstruction, ligature, or change of connections), either as part of a planned operation or as an emergency measure. They stress the concept that the surgical trunk of the left renal vein can be ligated and cut with no permanent functional damage to the left kidney.
A case of urinary malakoplakia involving both ureters and the bladder is presented. Ultrastructural data relating to the ureteric lesion are illustrated. Pale, dark and intermediate cells were involved in the pathological process. Features common and specific for these three types of cell are described. Dark cells are thought to be of a histiocytic nature, while the others are of either histiocyte or urothelial origin. Cytoplasmic inclusions were abundant in all three types in the form of single-or multicentred multilamellar bodies. It was not clear whether these were the product of secretion or phagocytosis. Michaelis-Gutmann bodies, on the other hand, were found to be due to the deposition of needle-like crystals inside pre-existing multicentred multilamellar bodies. Pathogens could not be demonstrated for certain. It is felt, therefore, that the aetiology of malakoplakia must be considered as debatable. Biochemical and immunological research directed to the detection of a possible enzyme deficiency is suggested, along with further ultrastructural investigation of the histogenesis of the pale and intermediate cells.
A technique of ureterectomy performed endoscopically in 5 cases, following nephro-ureterectomy for pelvic papillomatosis, without evident ureteric involvement, is described. This technique for its simplicity, speed of execution and innocuity, proved to be of practical utility.
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The authors report of case of splenogonadic fusion in abdominal retention, revising the subject from the aetiopathogenetic and diagnostic point of view. It is emphasized that correct recognition of the lesion can obviate useless orchiectomies, preserving normal function of the testicle at least from the endocrinal standpoint.
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AIM: We evaluated muscle-visceral interorgan flux of substrates in 8 critically ill patients in the flow phase after injury. SETTING: This study was conducted on critically ill patients admitted in ICU. PATIENTS: 8 patients were studied immediately after injury. RESULTS: We measured leg flux for oxygen, amino acids, glucose, lactate pyruvate, keton bodies, free fatty acids (FFA), free and total carnitine, and whole body oxygen consumption, nitrogen (N) balance and 3-methyl hystidine (3MEH) excretion during fasting and the second day of metabolic treatment (10.7 +/- 0.06 g x N x m-2 e 1035.5 +/- 3.9 kcal x m-2 x die). During fast the leg shows a net release of N, pyruvate, FFA and free carnitine while glucose, lactate and keton bodies fluxes are not different from zero. The energy balance of the leg is markedly negative (substrate for 79 kcal x m-2 burned for leg energy requirement and 347 kcal x m-2 released as a such). Assuming the body muscle tissue 4.5 times the leg tissue and knowing whole body energy balance, we were able to assess that the non muscular (visceral) part of the body resulted in a consistently positive energy balance. The metabolic treatment is able to match the energy expenditure and the substrate efflux of the leg (and the whole body muscle tissue). In fact the efflux of amino acids and FFA is reduced pyruvate blunted while glucose is remarkably taken up (the uptake of the whole muscle tissue accounted for 72% of the daily load). At the same time, the treatment blunts leg free carnitine and reduces body 3MEH output. Moreover, the caloric balance of the non muscular part of the body remains positive even if the qualiquantitative uptake of substrates is different from fasting. CONCLUSION: Substrates for energy requirements of visceral tissue came from muscular tissue. The metabolic treatment is able to modulate this process.