Biomedical subjects
Publications and source records attributed to G Brandt.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The importance of the incorporation of microbiology information into the laboratory cumulative report implies that continuing efforts need to be made to enhance the readability and style of such reports. In addition, the optimizing of laboratory work flow around a computer record-keeping system in microbiology is essential to guarantee technologist satisfaction with and usage of the system. The efforts and results of extending a commercially available system in the microbiology laboratory are discussed and compared with another approach using the same system base. The project led to smooth laboratory work flow and highly successful combined reports. Necessary software modifications are summarized.
It has been demonstrated that acute thioacetamide intoxication causes a significant increase in copper and zinc in the dystrophic liver of rats. Heart, skeletal muscle, cerebrum and cerebellum showed neither significant deviations of copper and zinc content, nor noticeable histopathologic changes in comparison with controls. Thus, hepatotropia in thioacetamide intoxication receives minimal pathological confirmation.
Electrodes made of vitreous carbon are inert, corrosion-resistant, inactive to electrocatalytic reactions and are especially biocompatible. Upon activation, they attain a capacitance of 20 to 40 mF and become "non-polarizable". Therefore, they should be particularly suitable as stimulating and sensing electrodes for cardiac pacemakers. The connective tissue layer that develops around the electrode because of the foreign-body reaction is less than 100 micron thick. The threshold rise, through lower than that of conventional Pt-Ir or ELGILOY electrodes, cannot be attributed exclusively to the connective tissue layer that is formed. Under favourable conditions, the threshold in animal experiments remains below 525 mV. Blood-spaces adjoining the electrodes are found at higher chronic threshold values.
Post-mortem atomic absorption spectrophotometry of the myocardium of a 14-year-old boy revealed a hundred-fold increase in copper. Further electrolyte analysis of the myocardium showed changes corresponding to metabolic heart muscle damage. Ultrastructural examination showed all the feature of a cardiomyopathy at the cellular level. Laser-Microprobe-Mass-Analysis demonstrated an inhomogeneous distribution of copper. An essential factor in the mechanism of death is heart damage.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A five day weight management camp for adolescents is described. Three components of weight management comprise of the camp's educational basis: 1) Nutrition Education, 2) Behavior Modeling, and 3) Physical Activity. Program planning and organizational methods are described. Thirty-five teenagers, age 13-17, attended the program. The mean weight loss for camp participants, measured at six months after camp, was 3.3 pounds. Triceps skinfold measurements showed an average decrease of 3.6mm after three months. The Wahler Self-Description Inventory was administered to measure favorable and unfavorable attributes through a self-evaluation process. Results showed a steady and continuous increase in favorable scores through the course of the camp and at the time of follow-up. Unfavorable scores were high prior to camp, followed by a sudden drop in unfavorable scores after the week of supportive therapy, followed by a leaving off effect of the 3-month follow-up session. A program evaluation by camp participants revealed that the residential camp environment was a useful approach to adolescent weight management therapy.
In the skeletal muscle of cats, semispherical stimulating electrodes having a radius of 1.2 mm deliver a mean threshold current of 0.15 mA, corresponding to 1.7 mA/cm2. These values are doubled within a period of four weeks after chronic implantation. In the case of non-polarizable electrodes the mean threshold voltage increases from 108 mV to 171 mV. The lowest individual values range between 50 mV and 60 mV at the time of implantation. The highest value is around 500 mV after four weeks. The high values have been observed with strongly polarizing ELGILOY electrodes. The chronic threshold energies vary between 3 x 10(-8) Ws for activated vitreous carbon electrodes and 17.5 x 10(-8) Ws for ELGILOY electrodes. There are two reasons for the low threshold energy of activated vitreous carbon electrodes. One reason is their low polarization, and the other is their better compatibility. Connective tissue layers with a thickness between 25 micron and 50 micron are found around well healed carbon electrodes.
Explore the source record for details and available documents.
The zinc content of the liver and the thigh muscle of the rat were measured by means of atomic absorption spectrophotometry under different conditions: standard diet, carbohydrate diet, an experimental dystrophy model and its recovery period. The influence of a parental mineral substitution on the whole body and the organ weight was studied. Carbohydrate diet caused a lower rise of the whole body weight, a decrease of the zinc content of the liver and an increase of the zinc content of the thigh muscle. In dystrophy model, the liver weight decreased to one fifth of the controls. The zinc concentration of the liver increased markedly, the zinc content of the whole liver is equal to that of control animals. The thigh muscle showed an increase of the zinc content, too. The parenteral mineral application had no effect upon the whole body weight and the organ weights. Little influences on the zinc content of the skeletal muscle were seen. The zinc content of parenchymatous organs varies markedly, and it is influenced by diets and disease. In the dystrophy model, zinc is concentrated in atrophic organs in order to protect the organism against zinc deficiency.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Zinc concentrations in autopsy material of human heart muscle, skeletal muscle, iliac crest, pancreas and liver were analyzed by atomic absorption spectrophotometry. Age dependent differences of zinc concentrations are seen in the liver. High values shows liver of premature infants, a minimum is measured in childhood which is followed by an increase in adult and senile patients. The other organs show no significant changes. Different diseases like diabetes or liver cirrhosis do not influence the zinc concentration in skeletal muscles and iliac crest. Long-term intensive care patients show a marked decrease in zinc concentration of the heart muscle. In the cirrhotic liver the zinc pool is depleted. In diabetes mellitus zinc concentration of the whole pancreas is normal, in cachexia it is critically decreased.