Biomedical subjects
G Brandeis
Publications and source records attributed to G Brandeis.
Polyarthritis as the initial symptom of secondary syphilis: case report and review.
The differential diagnosis of the patient with acute polyarthritis is lengthy. We present the case of a young man with acute inflammation of the knees and ankles in whom a diagnosis of acute rheumatic fever was initially considered. The clinical course and laboratory findings suggested that secondary syphilis was also a likely etiology of his problem. We believe that in some patients with acute polyarthritis, secondary syphilis must be seriously considered as part of the differential diagnosis.
Distribution of phosphatidylethanolamine arachidonic acid in platelet membranes.
Arachidonic acid (20 : 4) and other fatty acids and aldehydes in phosphatidylethanolamine (PE) present on the platelet surface was determined. Surface-exposed PE was isolated by using 2,4,6-trinitrobenzenesulfonate, a non-penetrating probe (Schick, P.K., Kurica, K.B. and Chacko, G.K. (1976) J. Clin. Invest. 57, 1221--1226). PE contains 50% total platelet arachidonic acid. Approx. 16% platelet PE is present on the platelet surface. The study showed that the fatty acid and aldehyde composition of PE on the platelet surface is virtually identical to that in PE present inside the platelet. Therefore, 8 nmol arachidonic acid are present in PE in the outer layer of the plasma membrane in 10(9) platelets.