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G Borysewicz

Publications and source records attributed to G Borysewicz.

16 recordsLinked to original sources
PubMed1990

[Evaluation of hygiene indices in studying the relations between oral hygiene and periodontitis based on epidemiologic studies].

The aim of the studies has been to determine the diagnostic clinical value of selected indices and to demonstrate their specific applicability under definite conditions. The study covered 184 subjects in two age groups: young persons aged 15-20 years, and adults being 20-45 years old. The oral hygiene was estimated by the following indices: OHI-S (Oral Hygiene Index-Simplified), Pl. I. (Plaque Index). C.P.I. (Cervical Plaque Index). The ++periodontium state was assessed by using the gingival index (G.I.). Periodontal index was defined by gingival index (G.I.), Russell's periodontal index (P.I.), as well as Kötzschke's periodontal index (K.I.). Sulcus fluid rate (S.F.R.) was also examined by Brill's method. The comparison of numerical values of the indices and statistical analysis of their cross correlation have shown that all of the indices having been involved in the study are of similar diagnostic value. However, C.P.I. appeared to be the best one, since the periodontitis indices most readily reacted to changes of its value. On the other hand, the oral hygiene index (O.H.I.-S) correlated more closely with inflammatory indices in adults, which suggests its particular applicability for examinations in this age group. (Pl. I.) may be used in young persons, in whom there are still no mineralized deposits of tartar. This index is easily determined, thus providing the possibility to evaluate the oral hygiene in quite a short time. Due to the fact that the quantitative measurements of sulcus fluid rate failed to reveal any statistically significant relation between the level of the sulcus fluid and periodontitis as well as oral hygiene in the youth, it has been ascertained that the sulcus rate measurement is of limited usefulness for clinically evaluating the state of parodontium, and may be resorted to in adult individuals only. It has also been disclosed that the resistance of parodontium to the action of pathogenic factors is greater in younger subjects.

Adolescent↗
PubMed1990

[Evaluation of immune response after thymectomy].

Immunological status of children after thymectomy performed at the age between 2 months and 15 years for teratoma in 5, and hyperplasia in 1. Cellular immunity parameters--as percent and total T lymphocyte count and their PHA reactivity, humoral immunity--as IgG, IgA, IgM concentrations, and phagocytosis--as phagocytosis index, NBT test, complement components--C3c, C4--concentration were evaluated between 6 and 12 years following surgery. No abnormalities within investigated parameters, nor the history of more frequent infections or other immunological disorder were detected.

Adolescent↗
PubMed1988

[Examination of CPITN indicator usefulness in specialist periodontal care].

Usefulness of CPITN indicator in specialistic parodontological care in 70 patients aged between 15-59 years has been estimated. One specialist was denoting the CPITN indicator on a special card and sending these patients to 1 out of 4 parodontologists in order to determine therapeutic management in a traditional way without knowing the value of CPITN. Comparing therapeutic needs based on CPITN value and on specialistic clinical examination it has been found that in 55.7% there existed a difference in parodontological needs and in 24.3% cases CPITN indicator determined therapeutic needs more precisely. It has resulted from utilization of diagnostic tool--WHO 621 tube. In 37.1% of the cases there existed inconsistency in determining therapeutic needs by both methods. It has resulted from the differences of both programs' assumptions. Although the CPITN system is intended for determination of parodontological needs of a certain community it can also be applied in specialistic parodontological care.

Adolescent↗
PubMed1981

[Normal values of serum IgD in children depending on their age].

In the Institute of Mother and Child in Warsaw there were determined normal values of IgG, IgA, IgM and IgE for different ages of children and youth. The determination of normal IgD levels is the last stage in this kind of studies concerning immunoglobulins. IgD levels were estimated in 372 cases in 19 age groups: in the cord sera, infant sera and older healthy children as well as in healthy adults sera. The IgD concentration was determined by Mancini method and given in I.U/ml. The results were statistically analysed. In all samples of cord sera no IgD traces were found. In infant sera (up to one year) IgD level is very low and was detected in 27% of cases. The percentage of detectability as well as the mean IgD concentration in serum grows systematically to the age of 15 years. There is high statistically significant correlation between serum IgD concentration and the age both for the arithmetical means (r = 0,33) and for geometrical values (r = 0,39). The correlation coefficients between detectability of serum IgD and age are higher (linear dependence-r = 0,67, square dependence - r = 0,75).

Adolescent↗
PubMed1979

[Immunochemical properties and therapeutic usefulness of the preparation Igalina produced by Biomed].

In order to obtain higher concentration of IgA-antibodies in commercial gammaglobulin preparations, used for treatment of hipo - and dysimmunoglobulinemia states, there are produced two preparations: "Gamma-A- Konzentrat " of Behringwerke and " Igalina " of Biomed . The first one was examined and described by us previously (4, 12). Now we present our studies on Igalina . The examinations were performed using electrophoresis on cellulose acetate, double diffusion in agar gell using 15 specific antisera to plasma proteins and immunoelectrophoresis with anti-IgG, IgA and IgM. There were detected traces of albumin, transferin , alfa2 macroglobulin, haptoglobin fibrinogen and presence of IgA, IgG and IgM. We also observed the split of IgG line in immunoelectrophoresis at the cathode and to Fc and Fab fragments. The concentrations of IgA, IgG and IgM were evaluated using Mancini method (IgA--920 IU/ml, IgG--1640 IU/ml IgM 2500 IU/ml). Concentrations of chosen antibodies in Igalina were: ASO--1000 U/ml, anti- Staphylolisins 8 U/ml, agglutinins antistaphilococal 1 : 320, diphtheria antitoxins 42 U/ml, agglutinins antithyphi 1 : 20----1 : 640. They were 4 to 100 times higher than in plasma serum. Isohaemagglutinins were not detected. Igalina was used for preventive treatment of children contacted with viral infections or therapeutically for children who demonstrated first symptoms of viral infections of respiratory tracts. Preparation was given 48 times to 40 children. This group included 19 newborns and 10 children with I and IV type of dysimmunoglobulinemia or hipoimmunoglobulinemia . Doses ranged from 0,5 ml up to 1,0 ml/kg body weight. Estimations of IgA, IgG and IgM concentrations in serum and saliva of children (using Mancini method) were carried out before injection of Igalina and on the third and seventh day after injection. Results of studies were statistically evaluated, and besides the lack of significant differences we found some rise of IgA and IgG concentrations. We would like to underline also that in 6 children with hipo or dysimmunoglobulinemia the levels of IgA and IgG reached normal value on the third day after injection of Igalina . Investigations of secretory piece in saliva in the same period were carried out too. In three patients we could find the presence of secretory piece just after injection of Igalina . We did not found antibodies to IgA in patients' sera after treatment. The clinical results of treatment as well as toleration of the drug were good and very good.

Adjuvants, Immunologic↗
PubMed1975

[A direct micromethod for transferrin level determination in human serum (author's transl)].

All the methods of quantitative estimation of transferrin concentration applied until recently have consisted in calculating the amount of this protein through the amount of iron bound in the blood serum. For this purpose the total iron binding capacity of serum (TIBC) has to be determined and then transferrin concentration is calculated. The calculation is based on the fact found by Ehrenberg and Laurell (1955) that two atoms of trivalent iron are selectively bound with one molecule of transferrin. The disadvantage of this method consists mainly in the necessity to carry out the measurement twice in every serum sample and in the large amount of material necessary for the analyses: this is a great inconvenience for pediatric clinics. The single-radial diffusion method in agar-gel was evaluated to be very advantageous for quantitative estimation of transferrin because of its simple technique and reaction specifity. The quantitative estimation is possible by the pilot calibration curve that represents the relationship of the diameter of a given circle and transferrin concentration. The quantity of material necessary for analysis amounts to not more than 5 mul of serum. Specific antitransferrin serum has to be imported and this seems to be the only reason why the said technique has not been used in Poland so far. The sera and vaccine laboratories in Warsaw have recently started to produce this antiserum and pure human transferrin. This has stimulated us to work out the single-radial diffusion method in agar based on Polish antiserum and Polish standard. The quality of the Polish specific rabbit antitransferrin serum and Polish pure human transferrin was tested by the immunoelectrophoretic method. The above findings provide the evidence that the Polish reagents are as good as those of the Behringwerke. Single-radial diffusion in agar gel should be carried out under the following conditions. 1) reaction temperature: 20-22degreesC 2) reaction time 24 hours 3) optimum concentration of antitransferrin serum in agar is 1:5.2. The error of the immunochemical method was determined experimentally and was found to be 9.05%. The results obtained with Polish and Behringwerke reagents were compared and were very similar.

Animals↗