[Review of 1000 hematuric patients in the hospitals in Rome, with special reference to the methods of diagnosis and therapy].
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Biomedical subjects
Publications and source records attributed to G Bonanni.
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Computed tomography was employed in 100 cases to examine the knee joint, without the use of intraarticular contrast medium administration. For greater resolution, only one leg of the patient was introduced into the gantry, and the limb being examined was immobilized and flexed at 8-10 degrees. Computed tomography clearly demonstrated all the anatomical structures that are of clinical interest such as menisci, cruciate and collateral ligaments, and articular and paraarticular soft tissues and tendons. The exact knowledge of the anatomy in axial view and in the indispensable sagittal and coronal reconstructions is fundamental in the identification of pathological conditions.
Computed tomography (CT) was used to examine the knee joint in 175 patients with various pathological conditions. In 118 of these patients a unique technique of study was employed. This technique is based on thin slices, a high resolution reconstruction program, and routine multiplanar reconstructions, without intraarticular contrast medium administration. In 36 patients studied with this technique, surgery was performed, thus permitting verification of the CT patterns. We concluded that CT may identify lesions of menisci, cruciate and collateral ligaments, and other pathologic conditions with at least 90% accuracy.
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Two adrenocortical adenomata causing Cushing's syndrome were examined by electron microscopy. Adenomatous cells were arranged in islets and contained ovoid nuclei with a prominent nucleoli. Mitochondria were polymorphic and displayed tubular and lamelliform cristae. Some cells were apparently devoid of lipid droplets and possessed an exceedingly well developed SER, the tubules of which were intermingled with small stacks of ribosome-studded cisternae, while other parenchymal cells contained large clumps of lipid droplets and scanty SER tubules. A conspicuous Golgi apparatus and many dense bodies of probable lysosomal nature were also observed. These findings suggest that the adenomata are derived from the zona fasciculata and that lipid-laden and lipid-free cells are, respectively, resting and actively secreting elements.
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A total of 63 twin pairs (22 MZ and 41 DZ), with one or both members affected by not organic stuttering and/or tics, have been drawn out of the Mendel Institute's twin file. Concordance of stuttering was observed in 10:12 MZ, but only in 2:19 DZ twin pairs; concordance of tics in 6:10 MZ and in 2:22 DZ twin pairs. Stuttering did not come out significantly associated either with other disturbances of language or with an IQ under the average; almost always it was possible to find out a precipitating factor. Significant relations between stuttering and tics could not be stated. Sex ratio, obtained regarding any affected subject separately, clearly turned in favour of males both in stuttering (32:12) and in tics (27:12). Stutterers and left-handers incidence in the families of stuttering subjects appeared significant in comparison with families of subjects with tics.
In 1973 the Mendel Institute, within the specialized services it offers to Italian twins, instituted psychopedagogic counseling for twins and their families. This service is carried out in the intermediate field between neuropsychiatry and social work. Cases involving family and social maladjustment were referring for counseling. During the academic year 1973-1974, the service examined 96 cases, of which 58 involved problems of school retardation and 38 involved family maladjustment because of changed parent-twin relationships. The counseling service aimed at achieving improved family and school relationships by means of various therapeutic interventions. The psychopedagogic counseling, besides the immediate therapy, has permitted deeper study of maladjustment by means of analyses of the twins' condition as a possible additional cause of the maladjustment itself. Analysis of the cases in this limited sample would seem to indicate an indirect incidence of the twin situation per se (couple effect), somewhat emphasized by the family and social environment.
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