Search PubMed⌕ Search

Biomedical subjects

G Blatter

Publications and source records attributed to G Blatter.

At least 37 records · Page 2Linked to original sources
PubMed1997

Segmental avascularity of the humeral diaphysis after reamed intramedullary nailing.

Although the clinical experience with reamed intramedullary nailing has been successful for the treatment of femur and tibia fractures, similar success has not been duplicated when this technique has been applied in the humerus. Although the cortical vascular response to nailing of the humerus is presently assumed to be similar to that of the femur, the response of the humerus to reaming has not been documented in vivo. The following case depicts avascularity of the humeral diaphyseal cortex as a complication of reamed intramedullary nailing and illustrates the sensitivity of the humerus to this treatment.

Adult↗
PubMed1996

The use of 2-deoxy-2-trichloroacetamido-D-glucopyranose derivatives in syntheses of hyaluronic acid-related tetra-, hexa-, and octa-saccharides having a methyl beta-D-glucopyranosiduronic acid at the reducing end.

Expeditious and stereocontrolled syntheses are reported of beta-D-Glc pNAc-(1-->4)-[beta-D-Glc pA-(1-->3)-beta-D-Glc pNAc-(1-->4)]n-beta-D-Glc pA-(1-->OMe), where n = 1, 2, and 3, which represent structural elements of the extracellular polysaccharide hyaluronic acid. Condensation of 4,6-O-benzylidene-3-O-chloroacetyl-2-deoxy-2-trichloroacetamido- alpha-D-glucopyranosyl trichloroacetimidate with methyl (4-methoxyphenyl 2,3-di-O-benzoyl-beta-D-glucopyranosid)uronate gave the disaccharide derivative 9, which was demethoxyphenylated and imidoylated to afford the pivotal disaccharide trichloroacetimidate 7. Condensation of 7 with methanol followed by O-dechloroacetylation gave the acceptor 8. Coupling of 7 with 8 gave the tetrasaccharide derivative 4. O-Dechloroacetylation of 4 followed by condensation with imidate 7 afforded hexasaccharide 5, which was transformed into octasaccharide 6 by a similar two-step procedure. Subsequent O-dechloroacetylation, transformation of the N-trichloroacetyl groups into N-acetyl, debenzylidenation, and saponification of 4-6 afforded the tetra- (1), hexa- (2), and octa-saccharide (3) derivatives in high yields, as their sodium salts.

Carbohydrate Conformation↗
PubMed1996

Knee joint muscle function after patellectomy: how important are the hamstrings?

Twenty-three patients who had undergone unilateral patellectomy were tested using the Cybex II isokinetic dynamometer 9 years postoperatively. The results were compared with the performance of the uninvolved joint. There was a good correlation between loss of the quadriceps muscle function and loss of the hamstrings muscle function at 60 deg/s (R = 0.7, P < 0.001). Patients who showed a loss of quadriceps function of less than 40% also maintained good hamstrings function. A good or excellent functional result could be expected in these patients. If the loss of quadriceps function was more than 40%, a proportional loss of flexion torque was seen, indicating a functional impairment of the knee joint muscles not solely attributable to the loss of the lever arm. Furthermore, all patients with a loss of peak flexion torque of more than 30% showed an unsatisfactory clinical result. The evaluation of the hamstrings muscles by measuring the peak flexion moment at 60 deg/s can therefore be used as a preoperative assessment and as a guideline for rehabilitation after patellectomy.

Activities of Daily Living↗
PubMed1996

The capsular imbrication procedure for recurrent anterior instability of the shoulder.

One hundred and thirty-eight patients (142 shoulders) who had recurrent anterior instability of the shoulder that was unresponsive to a specific physician-directed rehabilitation program were managed with an anatomical capsular imbrication reconstruction. The procedure included repair of the capsulolabral injury, when present, and reinforcement of the anteroinferior capsular ligaments with an imbrication technique that decreases the over-all capsular volume. The shoulders were divided into two groups: 108 shoulders in which the recurrent instability was related to a defined traumatic episode (Group I) and thirty-four shoulders with no distinct history of trauma (Group II). The anatomical capsular imbrication was the primary procedure in ninety shoulders and was used to treat at least one failed previous reconstruction in fifty-two shoulders. According to the grading system of Rowe et al., 93 per cent (132) of the shoulders had a good or excellent result at an average of five years (range, two or twelve years) after the operation. The results after a previous failed reconstruction were especially encouraging. Of the fifty-two shoulders that had had at least one previous reconstructive procedure, forty had an excellent result, five had a good result, four had a fair result, and three had a poor result. The results of this study suggest that this procedure restores stability while preserving a functional range of motion in patients who have symptomatic recurrent anterior instability of the shoulders, regardless of the etiology.

Adolescent↗