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Biomedical subjects

G Bernini

Publications and source records attributed to G Bernini.

54 records · Page 3Linked to original sources
PubMed1971

[Varicella].

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Adolescent↗
PubMed1971

[Herpes zoster].

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Adolescent↗
PubMedDate not supplied

Treatment of renovascular disease and of renovascular hypertension.

Treatment of occlusive lesions of renal arteries, defined as renovascular disease (RVD), is aimed both at preventing ischemic renal disease (IRD) and rescuing renal function through revascularization procedures, such as PTRA, endovascular stenting and surgical revascularization, as well as curing or improving hypertension in the presence of renovascular hypertension (RVH), i.e. hypertension caused by these vascular lesions. Preventive treatment of IRD is still an individual decision making process based on the type of renal lesions, degree of renal stenosis and progressive loss of renal mass as well as on immediate and late technical success of revascularization procedures together with their rate of complications. Rescue of renal function and-or prediction of the outcome of renal function after successful revascularization depends not only on the possibility of clarifying whether the decrease in renal function is a functioning-reversible phenomenon linked to renal hypoperfusion but also on the potential risk that the revascularization procedure may induce irreversible kidney damage. The rationale for treating RVH through revascularization procedures derives from the possibility of establishing a pathogenetic link between the occlusive lesions and hypertension, mainly through renal vein renin measurement and captopril renography and possibly their combination. Finally, medical treatment of hypertension is needed in patients who cannot undergo or refuse revascularization and whose blood pressure is not normalized by these procedures.

Humans↗
PubMedDate not supplied

[A multicenter study of child poisonings. Preliminary epidemiological results].

The project of a multicentre study of poisoning in children planned by 4 Italian pediatric departments to get epidemiologic and clinic information is presented. The study is carried out retrospectively on admissions during 1975-90 and prospectively during 1991-92. Poisonings are classified as not-confirmed, asymptomatic because of early treatment or symptomatic. In the latter group three degrees of severity are assessed. Diagnostic-therapeutic protocols will be elaborated and quality of the hospital care evaluated according to peer review methodology. Preliminary data on changing pattern of poisoning over the time and on main toxic agents involved in younger children are also reported. The first topic has been studied taking into account 1831 patients aged 0-13 years, admitted during 1977-79 and 1987-89. A decrease of exposures to drugs and an increase of poisonings under the age of 3 years have been observed in more recent period. On the other hand household products resulted to be the main poisoning agents in 1044 children under the age of 5 years during 1984-86. Lack of infant supervision by parents and possible influence of compulsory child resistant containers only for drugs are stressed. The findings suggest the need of health education campaigns in general population as well of safety devices for some domestic harmful products.

Age Factors↗
PubMedDate not supplied

[Care of oncologic child and his family: viewpoint of the pediatrician].

The authors report their considerations on the care of the oncologic childhood and their families. Various psychologic aspects are discussed, first of all the child and his cancer, how the parents and siblings face the disease, death and after. Finally they outline the role of pediatrician and the hospital staff.

Attitude to Death↗
PubMedDate not supplied

[Intestinal flora in children with celiac disease].

The variations of duodeno-jejunal bacterial flora are evaluated. 26 celiac children aged 2 to 7 years were divided in three groups. First group: 8 children in active phase of disease on a free diet; Second group: 10 children kept since one year on a gluten-free diet; Third group: 8 children challenged with gluten for some months. As the same time of the jejunal biopsy, a sample of duodenal juice was obtained for bacteriological examination; for this purpose were used the following culture media: Fluid thioglycollate medium (FTM), Blood-agar, Bile Esculin Azide Agar (BEAA), SF, selective for enterococcus, and MacConkey Agar. The results are: The number of bacterias in the first and third group is significantly higher (p less than 0.001 and p less than 0.05 respectively) than the second group with normal intestinal mucosa. Particular variations in bacteriological species in the three groups are not demonstrated. The excessive growth of bacterias in active phase of celiac disease could worse the absorption of lipids, vitamins, iron, and others substances and it could facilitate the local inflammatory processes in the small intestine.

Celiac Disease↗
PubMedDate not supplied

[Case report of a stage IV S neuroblastoma regressing without any aggressive treatment].

The authors describe a case of stage IV-S neuroblastoma in a boy forty days old with impressive enlargement of the liver whose left lobe was initially mistaken for splenomegaly. Regression was obtained without active treatment. Factors affecting the prognosis and treatment are briefly discussed. Is reported the association with persistent elevation of serum acid phosphatase.

Child, Preschool↗
PubMedDate not supplied

[Bilateral extrinsic ophthalmoplegia in infectious mononucleosis].

The AA. describe an eight years old child with extrinsic bilateral ophthalmoplegia associated with infectious mononucleosis. On the right (eye) a compromise of the VI (partial) and the III (total) pairs of cranial nerves was evident. On the left all extrinsic oculomotor nerves were interested.

Child↗
PubMedDate not supplied

Comparison of two application techniques of EMLA and pain assessment in pediatric oncology patients.

BACKGROUND AND OBJECTIVES: The study was designed to compare the analgesic efficacy of the local anesthetic EMLA when applied as a patch and as a cream in combination with a Tegaderm dressing to pediatric oncology patients undergoing repeated lumbar punctures. METHODS: The analgesic effect of the two products was assessed by a continuous or discrete visual analog scale in 24 children 3-16 years old, during two lumbar punctures. Distress was rated by use of the Observational Scale of Behavioral Distress. RESULTS: No significant differences were found between the pain and distress scores for the different preparations of EMLA. CONCLUSION: The EMLA patch and the EMLA cream are equally effective in alleviating pain associated with lumbar puncture. The EMLA patch simplifies and speeds up the application of EMLA. It also allows for control of the dose administered per application, thus preventing both over- and underdosing.

Administration, Cutaneous↗
PubMedDate not supplied

[The identification of minimal residual disease in the bone marrow and peripheral blood in neuroblastoma. The prognostic and therapeutic implications].

A highly sensitive and specific methodology to detect neuroblastoma cells in the bone marrow and peripheral blood of children with neuroblastoma is of critical importance for proper staging and treatment of these patients. In addition, patients with bone marrow infiltration at diagnosis need to undergo regular investigation to measure the effectiveness of chemotherapy (so called "in vivo" purging). Finally, the evaluation of autologous stem cells taken from bone marrow or peripheral blood is necessary to rule out or minimise the possibility of reinfusing tumor cells to the patient following myeloablative therapy. The authors provide a "state of the art" data on this complicated issue and give their preliminary results of their own experience, mainly concerning the immunocytological methods.

Biomarkers, Tumor↗