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Biomedical subjects

G Benhamou

Publications and source records attributed to G Benhamou.

At least 91 records · Page 5Linked to original sources

[Determination of lecithin-cholesterol acyltransferase. Studies on the precipitation of beta-lipoproteins by dextran sulphate (author's transl)].

Uncertainties in assays of lecithin-cholesterol acyltransferase (LCAT) are generally related to the degree of isotopic equilibrium obtained by rapid exchange of unesterified cholesterol between the different lipoproteins. A new method is presented based on the precipitation of serum beta-lipoprotein with sulfated polysaccharides prior to the LCAT determination. In the absence of Beta-lipoproteins, more than 7 per cent of serum free cholesterol is esterified in the first hour and the reaction rate is linear for about 2 h. LCAT activities with normal serum expressed as cholesterol esterified per microliter mol/1/h are lower than the values reported by others. The reason for this discrepancy is that free cholesterol specific activity in total serum does not reflect the true specific activity of LCAT cholesterol substrate.

Chemical Precipitation↗

[Septicemia due to Torulopsis glabrata].

The authors report a case of fungal septicemia due to Torulopsis glabrata, an unusual cause of fungus infections. This case was of interest clinically in view of the duration and tenacity of the infection on a surgical unit, where repeated blood cultures were positive for Torulopsis glabrata and the fungus was isolated from other samples during the same period. In the laboratory, the species identified was a common saprophyte of the mucosae and natural cavities of man; it seems to be only rarely pathogenic. Finally the course marked by numerous relapses was later favourable thanks to the use of antifungal agents chosen in the light of laboratory examinations.

Adult↗