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Biomedical subjects

G Benchetrit

Publications and source records attributed to G Benchetrit.

59 records · Page 4Linked to original sources
PubMedDate not supplied

Methicillin-resistant Staphylococcus aureus strains in Buenos Aires teaching hospitals: replacement of the multidrug resistant South American clone by another susceptible to rifampin, minocycline and trimethoprim-sulfamethoxazole.

The aim of this study was to characterize methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered from different infectious sites of hospitalized patients at two university hospitals. Fourteen isolates were analyzed by repetitive sequence based PCR (Rep-PCR), randomly amplified polymorphic DNA assay (RAPD-PCR), and pulsed-field gel electrophoresis (PFGE). We found that a prevalent clone of MRSA, susceptible to rifampin, minocycline, and trimethoprim/sulfamethoxazole (RIF(s), MIN(s), TMS(s)) was present in both hospitals in replacement of the multiresistant MRSA South American clone, previously described in these hospitals. The staphylococcal chromosomal cassette (SCCmec) type I element was detected in this new clone.

Academies and Institutes↗
PubMedDate not supplied

Effect of acute hypoxia on lung fluid balance in the prerecruited dog lung.

Lung lymph flow and protein transport were measured in eight anaesthetized dogs while acute hypoxic exposure (FIO2 = 0.10) was performed on prerecruited lung (achieved by an increased left atrial pressure). It was found that the lung lymph flow increase observed during hypoxia (from 71.8 +/- 47.5 to 100.8 +/- 78.4 microliters X min-1; p less than 0.05) was associated to an unchanged lymph/plasma protein concentration ratio (from 0.60 +/- 0.9 to 0.60 +/- 0.11). During recovery from hypoxia, lymph flow remained at a higher level than before hypoxia (respectively 87.8 +/- 49.5 and 71.8 +/- 47.5 microliters X min-1). These results suggest that the mild hypoxia-induced oedema is rather a high permeability oedema than an haemodynamic oedema. A graphic representation of protein clearance changes versus lymph flow changes was used in order to discriminate between high permeability and haemodynamic oedemas at their early stage.

Animals↗
PubMedDate not supplied

Effect of acute hypoxia on lung transvascular filtration in anaesthetized dogs.

The pulmonary transvascular filtration changes were investigated in nine anaesthetized open-chest dogs during acute hypoxic exposure. The tracheobronchial pulmonary lymph flow, the lymph and plasma protein concentration, the pulmonary vascular pressures and the cardiac output were measured during three consecutive steady states of about 2 h each: 1) base-line, 2) hypoxia (FIO2 = 0.10), 3) recovery from hypoxia. It was found that pulmonary arterial pressure and lung lymph flow increased in all animals during hypoxia, respectively from (average +/- SD) 19.4 +/- 4.5 to 27.1 +/- 5.6 Torr, and from 27.2 +/- 10.2 to 59.8 +/- 23.8 microliters . min-1; lymph to plasma protein concentration ratio remained unchanged. During recovery, lung lymph flow remained elevated in some animals, while it returned to its initial value in the others. Control experiments with normoxic hyperventilation in five dogs showed no increase in lymph flow. The extravascular water/blood free dry lung ratio was moderately increased in animals that had been made hypoxic (4.64 +/- 0.67) compared to a control group (3.46 +/- 0.36). These results suggest that acute hypoxic exposure causes an increased pulmonary transvascular filtration in anaesthetized dogs.

Acute Disease↗