Reye-like syndrome due to margosa oil poisoning: report of a case with postmortem findings.
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Biomedical subjects
Publications and source records attributed to G Baskaran.
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Vomiting, drowsiness, metabolic acidosis, polymorphonuclear leucocytosis, and encephalopathy developed in thirteen infants within hours of ingestion of margosa oil. Liver biopsy of one infant and necropsy examination of ICR strain mice after experimentally induced margosa-oil poisoning demonstrated pronounced fatty infiltration of the liver and proximal renal tubules as well as cerebral oedema. Electron microscopy demonstrated mitochondrial damage. These findings indicate that margosa oil may be involved in the aetiology of Reye's syndrome among Indians in Malaysia.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.