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Biomedical subjects

G Basile

Publications and source records attributed to G Basile.

69 records · Page 4Linked to original sources
PubMedDate not supplied

[Mirizzi syndrome].

Mirizzi's syndrome is a rare, but well described cause of obstructive jaundice which occurs in less than 1% of patients presenting for cholecystectomy. The syndrome is due to a stone impacted in the cystic duct or in the neck of gallbladder, causing compression or obstruction of the common emphatic duct. The clinic, physiopathologic, diagnostic and therapeutic aspects of this disease are described. The patient observed, arrived in emergency with obstructive jaundice and hyperpyrexia. Echography showed a remarkable dilatation of the biliary ducts, whereas endoscopic retrograde cholangiography (ERCP) showed an obstruction of the hepatic common duct of undefinable nature (stone, neoplasia). The surgical operation performed in emergency made clear the diagnostic doubt. Since inflammation impacted biliary duct and gallbladder, an incision of the gallbladder at its fundus was performed. In this way it was possible to extract about 40 stones of dimensions less than 1 cm, and one of 3 x 1 cm, impacted in the cystic duct, compressing the common hepatic duct. A partial cholecystectomy was performed and no connection between gallbladder and common emphatic duct (fistula) was found. The surgical operation led to complete resolution of the symptomatology. Therefore, the conclusions is drawn that Mirizzi's syndrome a rare but non infrequent pathology, finds its definition and complete resolution with surgical operation. Mirizzi's syndrome or obstructive jaundice due to extrinsic compression of principal biliary duct by a stone impacted in the cystic duct, is an uncommon complication of cholecystic lithiasis. Although this syndrome is rare (1%), it causes obstructive jaundice, sometimes dangerous, and serious complications as recurrent cholangitis.

Aged↗
PubMedDate not supplied

[Surgical treatment of arterial hypertension: experience and results].

Hypertension is a wide spread disease. In a small percentage of cases (nephrosclerosis, renovascular hypertension, endocrine hypertension) surgical treatment could be resolutive. The Authors describe their experience of the last five years about the subject, emphasize the technical detail taken and the results achieved; they outline the necessity to give the indications for surgery in wise manner considering clinical, laboratory and instrumental findings.

Humans↗
PubMedDate not supplied

[The surgical treatment of liver metastases from colorectal carcinoma: our experience].

Data from twelve patients who had hepatic resections for colorectal liver metastases were retrospectively analyzed to determine: 1) whether the use of the ultrasonic surgical dissector and the Argon laser can significantly simplify major hepatic resections and decrease both perioperative blood loss and postoperative morbidity and mortality, and 2) whether an adequate patients selection for surgery can effectively determine an improvement in recurrence rate. We performed 4 bisegmentectomies (2 of V and VI; 2 of VI and VII); 1 trisegmentectomy (V, VI, VII); 2 left lobectomies; 1 right hepatectomy and 4 wedge resections, using both the ultrasonic surgical dissector to fractionate and aspirate the hepatic parenchyma and to clear major vascular and biliary structures and the Argon laser for the coagulation of minor vascular and biliary vessels. The resected metastases averaged 5.5 cm (range: 1.5-7.5); blood transfusion requirements were significantly reduced from previous reports, averaging only 1.25 units (range: 0.3); the average operative time was 238 minutes (110 to 420 minutes). There were no operative deaths, operative morbidity rate was 16.6. The results indicate that the ultrasonic surgical dissector and the Argon laser have made a significant contribution to our marked decrease in the average blood loss and transfusion requirement. The long-term results seems to be improved by an adequate patients selection.

Aged↗
PubMedDate not supplied

[Pseudoachondrodysplasia (pseudoachondroplastic spondyloepiphyseal dysplasia). Description of 2 non-familial cases].

Two non familial cases of pseudoachondroplasia are reported. The patients, observed at 4 years and 6 months and 5 years respectively, show short-limb dwarfism with disproportionated long trunk and with normal head and face. Flattening of vertebral bodies with biconvex deformity and short tubular bones with irregular epiphyses and metaphyses are the major radiographic features. In these patients to state the type of genetic transmission is very arduous, as the genetic heterogeneity of the pseudoachondroplasia.

Achondroplasia↗
PubMedDate not supplied

[Scimitar syndrome with or without the "scimitar sign"].

The so called scimitar syndrome is a congenital malformation characterized mainly by the anomalous venous return of the right lung in inferior vena cava. Many structure of the lung may be involved. Usually lobation and bronchial distribution are abnormal, the right pulmonary artery is hypoplastic or absent, a partial anomalous artery from aorta (pulmonary sequestration) may be present, the entire lung is small and various degree of displacement of the heart to the right is detectable. Associated congenital heart defects may also be present. The name of the syndrome comes from the presence of this vessel (scimitar's sign) on routine chest x-ray. This paper describes the clinical and angiographic reports of four cases, which may represent, according a unique embriological interpretation, a different instances of this syndrome. The anatomic characteristic, the sign of scimitar, could be also absent, as in cases 2 and 3. In the case 2 there was complete absence of right pulmonary artery and in the case 3 a severe hypoplastic right pulmonary artery with unique small venous return in left atrium. The authors opinion is that all the anomalies of lung vascular connections, that result from interference with the normal growth of the lung bud, its separation from systemic vascular channels, and the establishment of the lesser circulation should be included. Because the different components of thie malformation can be present in various combination, the sign of scimitar is not pathognomonic to define the syndrome.

Child↗
PubMedDate not supplied

[Bladder hernia].

A case of bladder hernia in a 61 years old patient affected by benign prostatic hypertrophy is presented. Pre-operative diagnosis was made by cystography. After an adenomiomectomy of the prostate, the patient underwent the resection of the herniated bladder which gave the bladder its normal shape with only a slight reduction of its capacity. Inguino-scrotal bladder hernias are very rare; recognized predisponing factors are weakening of muscular and connective structures of the inguinal canal, and bladder hypotonia secondary to urethro-prostatic obstruction. These hernias, according to the anatomical position of the hernial sac, bladder and peritoneum, are classified in paraperitoneal (most frequent), intraperitoneal and extraperitoneal. The typical symptom of this disease is the two-stage micturition: the patient after a first spontaneous voiding, presses the mass and voids again. Other than cystography, useful diagnostic means are urography and cystoscopy which may confirm the diagnosis and rule out associated urinary disease. The treatment consists of either simple reduction of the bladder hernia, if the hernia is small, or resection of the herniated portion of the bladder, if the hernia is large or is associated with other diseases (e.g. tumors). Bladder resection is then followed by closure of the bladder wall in two layers and by inguinal hernia repair.

Hernia↗
PubMedDate not supplied

[Erectile dysfunction of vasculogenic origin: ultrastructural evaluation of cavernous myo-endothelial unit as prognostic index of penile revascularization].

The authors focus on the myoendothelial unit of the cavernous tissue, as they believe it to be of primary importance for the erectile event. The operations aimed at penile revascularisation were functionally unsuccessful, notwithstanding the haemodynamic resumption. This could be due to the myoendothelial unit not being perfectly integral. The authors have carried out 90 fine needle biopsies of the cavernous bodies in patients with erectile dysfunctions. These were evaluated using an ultra-microscope. The results of this ultra-structural analysis have highlighted various degrees of regressive phenomena, which can be linked to the severity and the duration of the symptom. The authors conclude by proposing that FNB should be used as a diagnostic tool for the selection of patients eligible for penile revascularisation.

Biopsy, Needle↗