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Biomedical subjects

G Bartsch

Publications and source records attributed to G Bartsch.

At least 343 records · Page 19Linked to original sources

Steroidal compounds (injectable and implants) affecting spermatogenesis in men.

The effect of androgen and different progestins on spermatogenesis was studied in young men with subfertility, prostatovesiculitis and haematospermia, and in older men with benign hypertrophy of the prostate. The compounds (testosterone, testosterone oenanthate, ethinyl oestradiol, megestrol acetate, ethinyl norgestrienone and Depo-Provera) were administered intramuscularly, orally or as subcutaneous silastic implants.

Adult↗

[Comparison of lipid concentrations in lung homogenates of newborns with and without hyaline membrane disease (author's transl)].

Quantitative and qualitative studies on lipids of the lungs were performed in babies who died during the perinatal period. The lungs were divided into organs with and without hyaline membranes respectively. Total lipids, phospholipids, neutral lipids, lecithins and sphingomyelins were determined. The fatty acid composition of total phospholipids and of lecithins is reported. A multivariate analysis of variance was used for the verification of significant differences in lipid content and in fatty acid composition with regard to the histological diagnosis. Taking at least two parameters (total phospholipids and C: 14-fatty acid or lecithin and C: 14-fatty acid into account, the two groups (lungs with and without hyaline membranes) were significantly different at the 5% level. The results are compared as well with the lipid content and composition of fatty acids of normal neonatal lung tissue as with observations regarding the lipids in amniotic fluid. The data obtained are discussed with regard to the development of lung maturity.

Amniotic Fluid↗

[Comparison of serum lipid concentrations in umbilical artery, umbilical vein and maternal vein blood (author's transl)].

Maternal serum lipids and lipids in umbilical artery and umbilical vein blood were examined immediately after delivery in order to relate maternal and fetal lipid metabolism. Total lipids, phospholipids, triglycerides, total cholesterol, cholesterol esters and free cholesterol were determined. The comparison of arterial and venous umbilical lipid levels showed a significantly higher concentration of phospholipids in the umbilical vein, indicating an enhanced flux of phospholipids from the placenta to the fetus. A positive correlation is established for the amounts of total lipids (p less than 0,05), triglycerides (p less than 0,01), phospholipids (p less than 0,05) and free cholesterol (p less than 0,005) between maternal and umbilical vein blood. It is suggested that free cholesterol passes the placental barrier unchanged. The other correlations are discussed as the expression of a factor influencing simultaneously the maternal and fetal lipid metabolism.

Cholesterol↗

[Lipid composition in placental homogenates of mature, premature and small for gestational age newborns (author's transl)].

Total lipids, phospholipids, and neutral lipids were determined in the placentas of mature, premature and small for gestational age babies. In addition the phospholipids and neutral lipids were calculated as percentage of total lipids. The distribution of fatty acids in placental phospholipids is reported. The difference found in the concentration of placental lipids is statistically significant at the 5% level between the groups of premature and small for gestational age babies. The increase of neutral lipids and the reduced content of phospholipids in placentas of small for gestational age babies are discussed as a possible sign of placental insufficiency.

Birth Weight↗

Ultrastructural-morphometric analysis of the rat prostate (ventral lobe).

A morphometric model, which provides information on the structure of the normal gland (ventral lobe) has been developed for the rat prostate. The model consists of morphologically defined space and membrane compartments, which are used to describe the specific components of the protein and enzyme synthesizing and secreting glandular cells. The results presented are relative to a cubic centimeter of prostatic tissue, a cubic centimeter of acinar parenchyma and glandular cell cytoplasm. Special interest was given to the cell compartments which are involved in protein and enzyme synthesis.

Androsterone↗

[Late results from patients with operated primary hyperparathyreoidism (mainly renal manifestation) (author's transl)].

By means of folow up of patients with operated primary hyperparathyreoidism (mainly renal manifestation) therefore neck exploration should be done on a broader scale and also the late results are reported. They indicate that a carefully considerated neck exploration is relatively free of risk. Of permanent postoperative complications in 83 operations made upon 76 patients only one case of a permanent unilateral paralysis of the recurrent laryngeal nerve was observed. The patients were subjectively free of symptoms; in the successfully operated patients stone recurrence or increase respectively growth of already existing urinary stones did not occur postoperatively. Those patients in whom repeatedly renal stones had been evident at the time of the operation, reported increased colics with partly spontaneous discharge of stones shortly after the operation; the i.v.p. controls showed no recurrent or additional formation of urinary stones in the patients, where we did successful neck exploration. The comparisons of the pre- and postoperative calcium levels indicate that the aim of the operation, normalisation of the calcium metabolism was obtained in almost all cases; only in 3 patients a hypercalcaemia remained. Mediastinotomy was performed only for two times. From these follow up we conclude that neck exploration carries a little risk compared to the high morbidity of primary hyperparathyreoidism (renal manifestation). Therefore neck exploration should be done on a broader scale and also in cases of diagnostic borderline values.

Adult↗

Echinococcal cyst of the adrenal gland.

A very rare case of echinococcal cyst of the adrenal gland is reported. Other organs were free of echinococcal cysts. Treatment consisted of surgical removal of the adrenal cyst through a subcostal incision.

Adrenal Gland Diseases↗