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Biomedical subjects

G Bartl

Publications and source records attributed to G Bartl.

At least 37 records · Page 2Linked to original sources

[A case of unilateral retinitis pigmentosa].

A case of unilateral retinitis pigmentosa observed over a period of 15 years is reported. The affected eye showed all typical pathologic manifestations, while in the healthy eye all findings--including ERG and EOG-- were normal. In spite of the unequivocal ophthalmological diagnosis the condition should be regarded as a tapetoretinal degeneration with the clinical picture of unilateral retinitis pigmentosa so long as there is no evidence that it is hereditary.

Adult↗

[Clinical experience with different methods of treating herpes corneae (author's transl)].

The modes of action of IDU and TFT were compared in tests employing them both as a monotherapy and in combination with iodine debridement in 60 patients suffering from superficial herpetic keratitis. The combination therapy was used for patients showing only dendritic stains in the corneal epithelium, while the monotherapy was used for patients who had additional lesions in the region of Bowman's membrane. Both with the monotherapies and the combination therapies the average duration of healing was shorter with TFT.

Debridement↗

[Clinical experience in treatment of glaucoma with timolol (author's transl)].

Forty patients with primary and secondary glaucoma were treated with the beta-blocking agent Timolol for six months. We used a 0.25% or 0.5% solution twice a day. In several cases sufficient pressure regulation was achieved by means of Timolol monotherapy. If pilocarpine or acetazolamide therapy was not sufficient we used a combination therapy with Timolol.

Acetazolamide↗

[Electro-ophthalmological responses in inflammations of various sections of the orbital visual pathways (author's transl)].

In a study of electro-ophthalmological responses of the EOG, the photopic and scotopic ERG, the OP and the VECP, in combination with fluorescein angiography and computerized perimetry, in 34 patients suffering from uveitis, chorioretinitis (lesions near the macula and at the periphery), papillitis or retrobulbar neuritis, the following results were obtained: Uveitis and chorioretinitis with lesions either near the macula or at the retinal periphery produce different responses; generally, pathologic responses of the EOG and ERG and normal VECP are obtained in cases of uveitis. Peripheral chorioretinal lesions lead to a diminution of the scotopic ERG, OP and EOG, in contrast to lesions near the macula, in which pathologically diminished amplitudes of the photopic ERG and VECP are found. In papillitis and retrobulbar neuritis, however, the most important peculiarity is the increase in latency and the decrease in amplitudes of the VECP, especially in retrobulbar neuritis.

Chorioretinitis↗

[Frontotransversal gunshot through both orbits leading to destruction of the bulbs in a case of attempted suicide (author's transl)].

In a case of attempted suicide a frontotransversal gunshot through both orbits led to symmetrical destruction of the bulbs and orbits. Examination revealed a rupture of both bulbs, fractures of the orbital roofs and floors, and destruction of the os ethmoidale. In the frontal cortex we found focal contusions. The physical effect of the gunshot on one hand, and the special anatomical relations of the orbit on the other, explain the serious consequences of orbital gunshot damages.

Brain Concussion↗

[Sjögren's reticular pigmentary dystrophy (author's transl)].

An examination of two families with reticular pigmentary dystrophy of the retina is reported, and typical findings are reviewed. Visual actuity, visual fields, dark adaptation and color vision were normal; the photopic ERG was normal or subnormal, while the scotopic ERG was normal. Only the EOG findings were pathologic in all of the subjects examined. A description of the various forms of reticular dystrophy and of its differential diagnosis is followed by a discussion concerning the classification of all varieties of this disease as patterned dystrophies of the pigment epithelium.

Adult↗

[Follow-up study in patients with neuritis retrobulbaris (author's transl)].

In 11 patients with multiple sclerosis (MS) and eight patients in whom MS was not verified visus, computerized perimetry, bipolar flash evoked cortical potential (H-EP) and pattern-reversal evoked cortical response (M-EP) were recorded in the acute stage and convalescent period of neuritis retrobulbaris. In the acute stage visual field deficiencies, diminutions of H-EP and M-EP amplitudes and increases in H-EP latencies were seen in both eyes in all cases. The most severe pathologic changes were found in the worst eyes in the group without MS. In the convalescent period a complete restitution of the electro-ophthalmological parameters was found in neither group of patients by statistical methods. Restitution was more common in patients who were not suffering from MS.

Adult↗

[Observations of the course of branch and central venous occlusions (author's transl)].

Electro-ophthalmological responses determined with EOG, photopic and scotopic ERG, flash VEP's and pattern reversal VEP's, in combination with fluorescein angiography and computerized perimetry, were evaluated in seven patients suffering from branch vein occlusions and in eight patients suffering from occlusions of the central retinal vein. The findings were as follows: In cases of branch vein occlusion and central retinal venous occlusion with good prognosis there was a normal or slightly subnormal response in all electro-ophthalmological examinations. In the cases of central retinal venous occlusion with poor prognosis, likely to lead to destruction of the nervous structures of the retina, the response was considerably weaker as regards photopic and scotopic b-waves, and especially VECP's.

Electrooculography↗

[Electroophthalmological, Fluorescence angiographical and computer perimetrical examinations in cases of contusio bulbi (author's transl)].

In seven patients with diminished visual acuity, caused by oedema of the retina after contusio bulbi, the EOG, the photopic and the scotopic ERG as well as the VECP, elicited by luminance (H-EP) on the one hand and by pattern reversal-stimulation (M-EP) on the other hand, were registered. These registrations were made both during and after the acute phase. The results were then compared with the results of the normal fellow eyes. Additional fluorescence-angiographic and computer-perimetric examinations were performed. All EOG and ERG components studied showed a significant reduction in the acute phase and a significant increase -- with the exception of the photopic b-wave -- in the regression of the oedema of the retina. However, the values of the affected eyes never reached the values of the normal fellow eyes. The different behaviour of the H-EPs and the M-EPs is striking. While the medium values of the H-EPs showed little reduction in all examinations, the M-EPs showed a highly significant decrease or increase, with the visual acuity and the M-EP showing corresponding behaviour.

Contusions↗

[Electroophthalmologic studies of papillitis, vascular papilledema and obstructed papilla].

The photopic electroretinogram (ERG) and the brightness visually evoked cortical potentials (HEPs) were recorded from patients with oedema of the optic disc caused by papillitis (7 patients), by vascular disease (10 patients) and by intracranial hypertension. For the ERG a Henkes-electrode in reference to an earlobe electrode was used. The H-EPs were recorded bipolar in the midline 5% to 25% and unipolar 15% in reference to an earlobe electrode (inion to nasion = 100%). For evaluation the amplitudes and the peaktimes of the a- and b-wave of the ERG were measured. In the H-EPs the amplitudes and the peaktimes of a negatives peak at approximately 70 ms (NGZ) and a positive peak at approximately 120 ms (PGZ) were obtained from the bipolar recording and a positive peak at approximately 100 ms (PGZ) and a negative peak at approximately 140 ms (NGZ) obtained from the unipolar recording were measured. The photopic ERGs of the affected eye showed normal values, however the H-EPs were distinctly pahtological. With the exception of the negative peaktime (NGZ) of the bipolar leads of the intracranial hypertensive papiloedema, all peaktimes were lengthened and amplitudes decreased. These findings were especially evident in the bipolar tracings of papillitis and unipolar tracings of intracranial hypertension.

Diagnosis, Differential↗

[Differential diagnosis of amblyopia and retrobulbar neuritis with electroophthalmologic methods].

The electroretinogram (ERG), the brightness visual evoked cortical potential (H-EP) and the pattern reversal visual evoked cortical potential (M-EP) were recorded from 7 patients with amblyopia and 5 patients with neuritis retrobulbaris. The ERGs and the H-EPs of the amblyopic eyes were normal whereas the amplitude of the M-EP was significant diminished. The parameters of the ERG recorded from the patients with neuritis retrobulbaris showed normal values, however the H-EPs were significantly decreased and the peaktimes were delayed. Also a decrease in the amplitudes of the M-EPs was noticed. This method is a usefull clinical contribution in the differential diagnosis between amblyopia and neuritis retrobulbaris.

Adolescent↗

[Electroophthalmologic and fluorescein angiographic studies in a case of exudative retinal detachment with spontaneous healing].

Electroophthalmological and fluorescein angiographic studies were performed on a 13 year old girl with exsudative detachment of the retina during a hypertensive crisis. The ERG showed a significant reduction during the course of the detachment. After healing the ERG values had improved as compared to those values recorded during the acute illness, but never reached normal levels. The lesions of the retina and the pigment epithelium caused by the detachment were responsible for pathological EOG. The fluorescein angiography showed circumscript and conglomerate lesions in the pigment epithelium.

Adolescent↗

[The electroretinogram and the visual evoked potential in normal and glaucomatous eyes (author's transl)].

The functional changes of the intraocular nerve structures caused by glaucoma were examined electro-ophthalmologically. The OPs, the photopic and scotopic ERG to examine the receptor and bipolar layers, as well as the EPs, elicited by luminance and pattern-reversal stimuli, for evaluation of the signal conduction in the optic nerve, were recorded. The problem was approached by way of three investigations: first was the question of which nerve structures are affected by glaucoma and exactly how the loss of visual field due to glaucoma can be determined. For this reason, 55 glaucomatous eyes with regulated intraocular pressure and different visual field losses were examined. The results show a functional diminution of all intraocular nerve structures in which the prelaminary part of the optic nerve is most affected. Differences in the visual field loss of both eyes can be well determined by the EPs. Second, the electro-ophthalmologic behavior in seven normal and eight pressure-regulated glaucomatous eyes was studied by gradually elevated intraocular pressure in order to obtain better insight into the functional pathology of glaucoma. The elevation of intraocular pressure was performed with a Müller spring dynamometer in five steps, depending on the ophthalmic blood pressure. The pressure behavior of the ERG components and the EPs is different. The amplitudes of the ERG components show a gradual decrease in normal as well as in glaucomatous eyes when intraocular pressure is increased, and are maintained when intraocular pressure reaches ophthalmic blood pressure. On the other hand, the EPs show a strong decrease in amplitude when intraocular pressure exceeds the mean ophthalmic blood pressure, particularly in the case of glaucomatous eyes. This behavior can be explained by a high pressure sensitivity of the preliminary part of the optic nerve, even greater in glaucomatous eyes. Third, the influence of pressure decrease on the electrical response was examined in glaucomatous eyes with chronic and acute pressure increase before and after pressure regulation. A mean pressure decrease of 37-13.6 mm Hg in ten eyes with chronic pressure increase led to no change in electrical responses other than a phase shift on the pattern-reversal EPs. In five cases with acute pressure increase, an amplitude increase on the luminance EPs was noticed after pressure regulation, with unchanged systemic blood pressure and almost unchanged ERG components. However, in one case an amplitude decrease on luminance EPs and ERG components was found with simultaneous blood pressure decrease. The increase of the amplitudes of the luminance EPs and the phase shifts of the pattern-reversal EPs can be explained as the functional improvement of the prelaminary part of the optic nerve caused by pressure decrease due to improved blood circulation in the prelaminary part of the optic nerve...

Acetazolamide↗

Cortical potentials evoked by a TV pattern reversal stimulus with varying check sizes and stimulus field.

With the use of television equipment the influence of check size and stimulus field on the pattern evoked cortical potentials was investigated. Maximum responses were found with 20' and 40' checks. The major part of the responses was initiated from a ring between 1.25 degrees and 2.5 degrees eccentricity, though relatively per stimulus area the response became progressively larger the smaller the stimulus field.

Evoked Potentials↗

[Comparative examinations in goniotrepanation and trabeculectomy (author's transl)].

In 20 patients with glaucoma simplex (15 cases) or angle closure glaucoma (5 cases) a trabeculectomy had been done on one eye and a goniotrepanation on the other eye within a period of a few days. As far as the operation-technic concerns neither ofthe two methods revealed a remarkable advantage nor a disadvantage. All patients have been controlled up to one year after the operations. There were only a few postoperative complications in both groups. There was no significant difference in the regulation of the intraocular pressure.

Aged↗

[TV-pattern reversal stimulus (VECPs) in determination of refraction (author's transl)].

Pattern reversal VECPs show a dependence on visual acuity and therefore are suitable for objective determination of refraction, this method, however, was of limited clinical use for two reasons, as, on the one hand, the required impulse parameter was difficult to change using the traditional mechanically functioning pattern stimulator and, on the other hand, diagnosis war very timeconsuming. Using a pattern impulse picture presented on a monitor by an electornic impulse apparatus all impulse parameters can easily be changed and throught he introduction of a microprocessorsystem the evaluation can be observed on-line.

Evoked Potentials↗