This report describes a hemangiopericytic meningioma with extracranial metastases in a 46-year-old man. Metastases developed in his right femur 2 1/2 and 4 1/2 years post operation; he received radiotherapy both times. Now 5 years after the primary operation the patient is alive but shows signs of a subcutaneous tumor in the area of the right posterior iliac crest, most likely metastatic tumor tissue. The case is discussed with special attention paid to the path tumor spread.

Femoral Neoplasms↗

PubMedDate not supplied

[Importance of forensic dental medicine].

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Dental Records↗

PubMedDate not supplied

Complications secondary to the use of standard bone wax in seven patients.

Ordinary bone wax, manufactured from beeswax, was used to stop bleeding from cancellous bone in elective surgery among seven women. Five of them had a resection of a calcaneal exostosis and bursa at the insertion of the calcaneous tendon, one underwent a resection of a medial exostosis of the first metatarsal head, and one had an acromial resection. Postoperatively, all patients had disabling local pain and tenderness. Three of them developed firm visible swellings where bone wax had been used, which was easily palpable under the intact skin. At reoperation, 4 to 52 months later, masses of brown, soft granulation tissue were excised in all patients. Five of seven were relieved from pain. Microscopically, a bone wax granuloma with marked foreign body reaction was seen in all patients.

Adolescent↗

PubMedDate not supplied

Guided tissue regeneration and local delivery of insulinlike growth factor I by bioerodible polyorthoester membranes in rat calvarial defects.

Thirty 8-week-old male Wistar rats were randomly allocated into three groups of 10 rats each. A 5-mm defect in the left parietal bone was made in each rat. In the defects of the first group of rats, no implant was used (control group). In the second group, polyorthoester membranes were placed in the defects without active substance. In the third group, polyorthoester membranes were placed with insulinlike growth factor I. The rats were sacrificed 6 weeks postoperatively. Bone formation in the defects was quantified by computer-assisted measurements of the area of the residual defect on radiographs. Host-tissue response was evaluated by light microscopy. The area of residual bone defect was greatest in the control group, less for the defects with polyorthoester membrane without active substance, and least for the defects with polyorthoester membranes with the growth factor. During histologic evaluation, no inflammation was seen, and only traces of the polyorthoester were detected in the defects with polyorthoester membrane with or without the growth factor.

Animals↗