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Biomedical subjects

G Bang

Publications and source records attributed to G Bang.

At least 37 records · Page 2Linked to original sources
PubMed1992

Regeneration of calvarial defects by a composite of bioerodible polyorthoester and demineralized bone in rats.

A study was performed to evaluate regeneration of defects in rat calvaria either unfilled or filled with a bioerodible polyorthoester only, demineralized bone only, or a composite of both. At 4 weeks, histological and radiographic studies showed that defects filled with a composite of bioerodible polyorthoester and demineralized bone or demineralized bone alone were bridged by bone. Unfilled defects or defects filled with polyorthoester only did not heal. The polyorthoester caused slight inflammation that subsided by 3 weeks, and only traces of the filler could be detected at 4 weeks. The polyorthoester provided local hemostasis when used either alone or in composites with demineralized bone. The composite implant was moldable, easily contoured, and technically easier to use than demineralized bone alone.

Animals↗
PubMed1992

Inhibition of heterotopic osteogenesis in rats by a new bioerodible system for local delivery of indomethacin.

A study was done to evaluate the effect of a system for the local delivery of indomethacin on demineralized bone-induced formation of heterotopic bone in the abdominal muscles of rats. Two separate investigations were conducted on a total of forty-eight Wistar rats. In both series, two types of implants were used: polyorthoester and demineralized bone (Group A, the control group) and polyorthoester with 5 per cent indomethacin and demineralized bone (Group B, the experimental group). In the first series, host-tissue responses and osteoinduction were evaluated histologically at two, three, and four weeks after the implantation. In the second series, the formation of bone was quantified on the basis of uptake of 85Sr at four weeks after the implantation. The polyorthoester system for the local delivery of indomethacin significantly inhibited demineralized bone-induced heterotopic formation of bone, as demonstrated by light microscopy and by uptake of 85Sr. The polyorthoester, with or without the drug, caused little tissue reaction and was resorbed almost completely at four weeks.

Abdominal Muscles↗
PubMed1992

The effect of a composite of polyorthoester and demineralized bone on the healing of large segmental defects of the radius in rats.

The effect of a composite of demineralized bone mixed with polyorthoester on the healing of large segmental defects in the rat radius was studied. Sixty male Wistar rats were divided into four groups, A through D, and an osteoperiosteal diaphyseal defect of 50 per cent of the length of the bone was made in the right radius of each rat. In Group A, the defect was filled with polyorthoester and demineralized bone; in Group B, demineralized bone; and in Group C, polyorthoester. No material was implanted in the defects in the Group-D rats. The rats were killed fifty days postoperatively. The formation of bone in the defects was quantified with computer-assisted measurements of the area on radiographs. The host-tissue response was evaluated with light microscopy. Defects that had been filled with the composite of polyorthoester and demineralized bone or with demineralized bone alone showed regeneration of bone corresponding to 93.6 and 77.6 per cent of the area of the defect, respectively. Defects that had no implant or that had been filled with polyorthoester alone showed significantly less formation of bone. No inflammation was seen with light microscopy, and only traces of the polyorthoester could be detected in the defects that had been filled with the composite or with polyorthoester alone.

Animals↗
PubMed1991

Geographic stomatitis: report of 6 cases.

The macro- and microscopic appearance and results of microbiologic and immunohistochemical investigations in six patients with geographic stomatitis are described. On the background of similarities in both the clinical, histologic and immunohistochemical findings it is felt that psoriasis and stomatitis geographica are related lesions.

Adult↗
PubMed1991

Alveolar ridge augmentation in rats by combined hydroxylapatite and osteoinductive material.

The purpose of this study was to examine if increased bony ingrowth developed when hydroxylapatite was implanted together with an osteoinductive substrate. Dense hydroxylapatite granules (HA) (Calcitite, Calcitek, San Diego, CA, USA) were mixed with equal volumes of allogenic, demineralized, lyophilized dentin or bone and implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal muscles in rats. Light microscopic evaluation revealed that HA was surrounded by fibrous connective tissue containing foreign body giant cells and it had neither an osteoinductive nor an osteoconductive effect. The newly formed bone induced from the implanted allogenic, demineralized, lyophilized dentin or bone was never found in close contact with the HA and did not incorporate the implant.

Abdominal Muscles↗
PubMed1991

Alveolar ridge augmentation in rats by Bio-Oss.

The purpose of the study was to examine if Bio-Oss initiated osteoinduction or osteoconduction when implanted into rats. Sintered and unsintered granules of the anorganic bovine bone Bio-Oss was implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal muscles of rats. Light microscopic evaluation revealed no osteoinduction or osteoconduction in connection with sintered or unsintered Bio-Oss. A foreign body reaction was observed around both forms.

Abdominal Muscles↗
PubMed1991

Sarcoidosis of the uterus.

Sarcoidosis rarely involves the female genital tract. A report is presented of 2 cases of sarcoidosis of the uterus. In the first, the diagnosis was made by biopsy of the portio vaginalis uteri which was amputated during the Manchester operation for genital prolapse. In the second case the diagnosis was made by endometrial curettage for postmenopausal vaginal bleeding. Neither of the women exhibited signs of generalized sarcoidosis.

Aged↗
PubMed1990

[Localized amyloidosis of the lower respiratory tract].

Primary amyloidosis localised to the lungs can simulate different types of lung diseases such as tuberculosis, carcinoma and repeated infections in the lower respiratory tract. The possibilities of treatment are limited. The prognosis is usually good, except when there is diffuse pulmonary involvement. Such patients can develop progressive respiratory failure The mechanism of amyloidogenesis is unclear. At the cellular level the macrophage may play a central role.

Amyloidosis↗
PubMed1990

Intramuscular hemangioma in the oral region: report of three cases.

The occurrence of intramuscular hemangioma in an intraoral or perioral localization is rare, and a thorough knowledge of these tumors is necessary for adequate diagnosis and treatment. Three cases are presented with discussion, and their histopathology and differential diagnosis are discussed. An adequate primary excision is necessary to avoid recurrence.

Adolescent↗
PubMed1990

Alveolar ridge augmentation by osteoinduction in rats.

The purpose of this study was to evaluate bone substitutes for alveolar ridge augmentation by osteoinduction. Allogenic, demineralized, and lyophilized dentin and bone was tested for osteoinductive properties in order to establish an experimental model for further studies. Implantations were performed subperiosteally on the premaxilla and heterotopically in the abdominal muscles of rats. Light microscopic evaluations revealed that all allogenic, demineralized, and lyophilized dentin and bone implants induced new bone formation. No inflammatory or foreign body reactions were observed.

Abdominal Muscles↗
PubMed1989

Clear cell odontogenic carcinoma: report of three cases with pulmonary and lymph node metastases.

Three cases of a newly described rare odontogenic tumor are reported. One patient died with pulmonary metastases, one had an associated odontogenic cyst and one exhibited regional lymph node metastasis. The cases lend support to the odontogenic origin and metastatic capability of the clear cell odontogenic tumor. The authors recommend aggressive therapy and believe that the tumor should be considered a clear cell odontogenic carcinoma.

Aged↗
PubMed1989

New malignancy grading is a better prognostic indicator than Broders' grading in oral squamous cell carcinomas.

The prognostic value of histopathologic grading of oral squamous cell carcinomas (SCC) has varied from not any to highly significant. We have retrospectively studied all (130) SCCs registered in Norway 1963-72 in the buccal and maxillary alveolar mucosa. From 68 of these cases biopsy specimens of acceptable quality were obtained. Broders' method of grading was compared with a modification of a recent malignancy grading system recommended by Anneroth et al. which was performed only within the histologically most invasive areas of the tumors. Cox's multivariate survival analyses showed that this grading in the invasive sites had highly significant prognostic value. Broders grade had no prognostic value. The stage of tumor had also prognostic value. These highly significant results indicate that the histologically invasive areas may be primarily responsible for the clinical behavior of the tumor, and this may be of importance for the choice of therapy for oral SCC.

Carcinoma, Squamous Cell↗
PubMed1989

Dental and jaw changes in primary hyperoxaluria.

A case of teeth and jaw changes in primary hyperoxaluria is described. The patient, a 25-yr-old man, was treated by kidney transplantation twice, and finally by combined liver and kidney transplantation. The teeth and jaw changes consisted of deposition of oxalate crystals in the gingiva, in the pulp and in the vicinity of bone and dentin. The resorption of bone and dentin was extensive.

Adult↗
PubMed1989

Infantile fibrosarcoma in the mandible: case report.

A case of an infantile fibrosarcoma in the mandible is described. The primary tumor was seen in a 2.5 yr-old boy. In spite of repeated surgical interventions the tumor recurred five times during a 15-yr period, but no metastases have been observed. The difficulty in arriving at a correct histopathologic diagnosis on an unusual tumor in the oral region is demonstrated by the fact that 16 consulted pathologists suggested a long list of different tumors. The treatment of choice seems to be radical surgery. The patient has remained well and without recurrence for the last 7 yr.

Adolescent↗
PubMed1988

An explosive decompression accident.

Four divers in a compression chamber system were suddenly decompressed from 9 atm to 1 atm. One of the divers was about to close the door between the chamber system and the trunk when the accident happened. He was shot out through the door and severely mutilated. The three others died on the spot. The autopsy results are described. The most conspicuous finding was large amounts of fat in the large arteries and veins and in the cardiac chambers, as well as intravascular fat in the organs, especially the liver. This fat can hardly have been embolic, but must have "dropped out" of the blood in situ. It is suggested that the boiling of the blood denatured the lipoprotein complexes, rendering the lipids insoluble.

Accidents, Occupational↗
PubMed1987

Congenital epulis in the newborn.

Neoplasms in the oral cavity are generally recognized during the routine examination of the newborn. Lesions arising on the alveolar processes of the jaws may interfere with nursing and respiration. This paper reviews the congenital epulis (CE) in the newborn. A case of CE arising on the maxillary alveolar process is reported. Due to the indication for removal of these benign tumours in the neonatal period they should be recognized as early as possible.

Alveolar Process↗