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Biomedical subjects

G Ballerini

Publications and source records attributed to G Ballerini.

At least 37 records · Page 2Linked to original sources
PubMed1985

A contribution to the pathology of acquired plasma factor XIII deficiency.

The biologic activity of Factor XIII was measured in four groups of patients: 20 with liver cirrhosis, ten with acute DIC, 30 with acute leukemia with DIC, and 20 with acute leukemia without DIC. In all groups, the plasma Factor XIII transamidating activity was reduced, but this deficiency was more evident in patients with DIC alone or with leukemia and DIC. The immunologic determination of the a and b subunits of Factor XIII was also performed. Both subunits were below the normal range in the groups of patients studied, except for subunit b, which was normal in patients with leukemia without coagulopathy. Acute DIC patients showed an equally reduced level of both subunits, whereas in patients with leukemia, even in the presence of a complicating coagulopathy, a lesser decrease of subunit b than subunit a was found. Both subunits were equally reduced in patients with cirrhosis, suggesting an impaired synthesis of these proteins. In conclusion, our findings do not support the use of Factor XIII subunit measurements in distinguishing between thrombin- or protease-mediated consumption coagulopathy, and they seem to suggest that the deficiency pattern of the subunits is not accounted for by a simple pathogenetic mechanism.

Acute Disease↗
PubMed1984

[Platelet hyperfunction in prethrombotic vascular disease].

In 3 groups of patients with high thrombotic risk (diabetes mellitus, hyperbetalipoproteinemia, hypertension) the platelet aggregation and the level of circulating platelet aggregates were found statistically higher than in normal controls. In addition, platelet aggregation in diabetic patients was found statistically higher than in the other 2 groups of patients. Therefore these 2 parameters of platelet function are useful for the screening of patients with potential risk for thrombosis allowing a more selective and defined prophylaxis, both of thrombosis and atherosclerotic complications.

Adult↗
PubMed1984

Ultrasonic patterns of parotid masses.

The aim of this study was to define sonographic patterns of expanding parotid lesions. Over a 2-year period, 39 parotid gland masses were examined. Gray-scale sonography with a static scanner using high frequency transducers (5 and 7.5 MHz) provided refined visualization of the normal structure of the gland and the space-occupying mass. There are different sonographic patterns for different types of mass. Lesion malignancy should always be suspected when there is a clearly echogenic mass, especially one with an irregular distribution of the echoes, posterior attenuation, and rough margins (these sonographic features are of no value for lymphomas). All benign lesions have regular margins and are sonolucent at normal gain settings. It is possible to obtain a characteristic sonographic pattern for each specific benign lesion by varying the gain.

Adenolymphoma↗
PubMed1983

[Transabdominal echotomography in the staging of tumors of the bladder].

Transabdominal wall ultrasonography in the study of the bladder tumours is a simple and athraumatic method. In this prospective study the ultrasonographic patterns considered allow the differentiation among three principal classes: I group: superficial tumours with intact bladder wall; II group: invading tumours with the disappearance of the bladder wall behind the tumour (it is not possible to differentiate a superficial muscle involvement to a deeper invasion); III group: tumours with extra-vesical extension. The ultrasonic stage grouping has been compared with pathological staging, in a series of 46 patients (1981-1982). The I group (superficial tumours), corresponding to Pis-P1 pathological stage, and the III group, corresponding to P4, have a good accuracy (85% and 87,5%). In the II group, corresponding to P2-P3, the accuracy is less (72%) and it is not possible to differentiate between the two pathological stages. Transabdominal wall ultrasonography should be the first investigation in the preoperatory staging of bladder tumours.

Humans↗
PubMed1978

[Etiopathogenetic considerations on so-called moderate thrombopenia in young women].

Twenty cases of moderate thrombocytopenia in young women were examined in an assessment of the nosological status of this form. Parameters enjoying pathogenetic significance were distinguished in some instances: 4 cases displayed dysendocrinopathy, 2 the signs of consumption coagulopathy, 3 an antibody situation attributable to compensated autoimmune thrombocytopenia, and 3 a probable central inhibition of thrombocytopoiesis due to drugs. Since no significant cause could be determined in the remaining 8 cases, it can be said that this syndrome occupies a special place among the forms of chronic thrombocytopenia.

Adolescent↗