Biomedical subjects

G Baldini

Publications and source records attributed to G Baldini.

112 records · Page 7Linked to original sources

PubMedDate not supplied

[Lactate dehydrogenase isoenzymes in HIV-positive children].

Considering that in the HIV infection there is a precocious deterioration of humoral immunity with rapid turn-over of cellular B clones, we have evaluated the conduct of serum lactate-dehydrogenase activity (LD, EC 1.1.1.27) and its isoenzymes in 21 children born from HIV-positive mother respect to a control group (30 subjects). Furthermore we have checked the existence of a probable correlation between those and other clinical and immunologic parameters (total lymphocytes, CD4/CD8, immunoglobulins, classification according to the Atlanta CDC). In seropositive children we saw, respect to those evolved towards P3 stage, a significantly raising of LD4 (also vs. control group) for likely pulmonary parenchyma's damage, LD3 for B immature lymphocytes' increase and a reduction of LD1 (also vs. control group) for mature clones' decrement. Furthermore in seropositive subjects there was the existence of a direct correlation between LD1 and CD4/CD8 values. As such, the evaluation of LD isoenzymes can establish an useful element in the clinical monitoring of seropositive children.

CD4-CD8 Ratio↗

PubMedDate not supplied

[The asthmatic child and sports].

Many asthmatic children are more disabled by exercise-induced asthma (EIA) than by other asthmatic attacks. Recent attention has focused on the pathophysiology of EIA and its prevention. Only within the past few years the effects of exercise programs have been examined carefully in children with asthma. Thus, they can increase work tolerance and fitness with a beneficial effect of physical training on EIA. Adequate training intensities would be possible if EIA could be prevented by premedication and if a type of exercise was chosen which gave good cardiopulmonary training. Although swimming is their optimum sport (experience of authors), asthmatic children should be encouraged to embrace a full and varied program of sport. Many sportsmen and women who have asthma are able to compete at the highest level and gain olympic and world honours.

Asthma↗

PubMedDate not supplied

Lamellar and "club-shaped" corpuscular nerve endings in human gingival mucosa. A light and electron microscopic study.

A study on the presence of corpuscular nerve endings in human gingival mucosa was performed using both light and transmission electron microscopic (TEM) techniques. Both round and oval lamellar corpuscles were detected by light microscopy. They were located either subepithelially, close to the basement membrane, or within the papillae, deeply invaginated into the overlying epithelium. TEM techniques showed convoluted structures with unmyelinated fibre arborizations leading to an afferent fibre supported by the so called lamellar cells. The presence of blood vessels, collagenous fibrils, desmosome-like junctions, cytoplasmic organelles, as well as the similarity with some previously described mechanoreceptors, suggested the role of such corpuscular nerve endings in transmitting a nervous impulse induced by mechanical stimulation. Other simpler structures were also observed and named "club-shaped" corpuscles: they could support the more complex ones in responding to the strengths and the movements directly influencing the gingival mucosa.

Gingiva↗

PubMedDate not supplied

[Correlations of the response to the prick test and blood levels of specific IgE in children].

A good correlation between intensity of prick test result and haematic levels of specific IgE is a fundamental presupposition to affirm that both diagnostic methods are equivalent to demonstrate a condition of IgE-mediate hypersensitivity. Using a retrospective analysis of our data, we intended to examine the degree of this correlation for the most common food and inhalant allergens. The comparison between prick test results and specific IgE haematic levels for all considered allergens-shows a good concordance of F.A.S.T. for prick negative results and a sharp discordance of F.A.S.T. for prick positive results. Both food and inhalant allergens are equally involved in the discordance between the tests. Therefore, we cannot exclude the possibility of clashing results between prick test reaction and specific IgE haematic levels, even in further analysis would be necessary to obtain more reliable verifications.

Adolescent↗