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Biomedical subjects

G B Scott

Publications and source records attributed to G B Scott.

At least 91 records · Page 5Linked to original sources

A morphometric study of the laryngeal saccule and sinus.

A morphometric study of 111 larynxs from both sexes was performed with the initial intention of assessing the incidence of asymptomatic laryngeal pouches. Certain basic measurements were made also to determine the dimensions of the laryngeal saccule and sinus relative to the height and width of the larynx in the two sexes. Asymptomatic pouches were found in 2 patients, one from each sex and there was no obvious difference in the height of the saccule relative to the height of the larynx in the two sexes. However, since the male larynx was deeper in the anteroposterior plane relative to its height, the male saccule tended to be relatively shallower than the female.

Adolescent↗

A quantitative study of microscopical changes in the epithelium and subepithelial tissue of the laryngeal folds, sinus and saccule.

The folds, sinuses and saccules from III unselected larynxs removed at autopsy were examined microscopically for epithelial and subepithelial abnormalities. Squamous metaplasia and 'dysplasia' of the vestibular and vocal folds respectively, particularly the former, were commoner in men than women. Two distinct varieties of 'dysplasia' were observed, and the close relationship between 1 of them and changes, possibly of vascular origin, in the subepithelial tissues of the vocal fold suggested cause and effect.

Adolescent↗

Ulcerative colitis in apes: A comparison with the human disease.

The pathological changes in the colons of two young gorillas and an adult orang-utan which developed diarrhoea and died, are described. Since no causative agents could be identified and the changes were indistinguishable from the active phase of ulcerative colitis in humans, these cases were considered examples of this disease in apes. Evidence of early healing was found in one case and the suitability of apes and monkeys as possible animal models of the human disease is discussed.

Animals↗

The pathology of measles in Abyssinian Colobus monkeys (Colobus guereza): a description of an outbreak.

The pathological changes found in four Abyssinian Colobus monkeys (Colobus guereza) dying of measles are described. Warthin-Finkeldey giant cells were plentiful in the lymphoid tissue and spleen, in the mucosa of the alimentary tract and in the lungs, where they accompanied a non-suppurative pneumonia. In the alimentary tract they were most frequent in the colon when an associated colitis was present. Measles virus was recovered from the lung tissue of one animal, the virus being neutralised by both human and rhesus monkey anti-sera. This together with the close similarity between the pathological changes in human and monkey measles, supports the contention that the two diseases are one and due to the same virus.

Animals↗

Xanthogranulomatous pyelonephritis. A comparison of the disease in the cat and man with special reference to the origin of the fat.

The origin of the intracellular fat in human xanthogranulomatous pyelonephritis has been the centre of some discussion in the past. A report of a case in a domestic cat is of interest as normal feline renal epithelium is rich in stainable fat. A comparison of the human and feline varieties of xanthogranulomatous pyelonephritis reveals certain fundamental differences between the two and reinforces the view that the fat concerned in the human disease does not originate in the renal epithelium.

Animals↗