Search PubMedSearch

Biomedical subjects

G B Irons

Publications and source records attributed to G B Irons.

11 recordsLinked to original sources

Management of radiation necrosis and advanced cancer of the chest wall in patients with breast malignancy.

Aggressive resection, with individualized reconstruction by several methods, is of value in many patients with radiation necrosis and/or advanced breast cancer of the chest wall. Although this does not always significantly lengthen survival, it can improve the quality of life markedly in many instances. Remarkably large defects can be reconstructed with single-stage procedures.

Adult

Panniculectomy and abdominoplasty.

The series involved 123 patients who had 126 excisions of the abdominal wall. In 84 patients, a large pannus of fatty tissue and skin was excised to expedite the approach to intra-abdominal disease or the repair of hernias. In 39 patients, the operation was an abdominoplasty done to improve the appearance of the abdomen or to excise relaxed or redundant tissues. Complications were minimal. The experience suggests that the surgeon should consider and utilize techniques to improve the general function and appearance of the abdominal wall and yet not compromise the treatment of the patient's major problem.

Abdominal Muscles

Experience with and comparision of methods of reduction mammaplasty.

Experinece with bilateral reduction mammaplasty in 213 patients has been reviewed. Complications, while not infrequent, are rarely of a serious or lasting nature. In the experience of the authors, the McKissock procedure has yielded the most consistently good results, although very good results were occasionally achieved with all of the other techniques employed.

Adolescent

Chemical burns and skin preparation solutions.

Skin preparation burns associated with chemical agents are uncommon. They occur most frequently in those patients placed in the lithotomy position undergoing gynecologic operations, the burn being on the buttocks, and in those undergoing orthopedic operations, the burn being on the extremities and under a tourniquet. Thimerosal has been the most common agent to be implicated. The basic mechanism involves irritation coupled with maceration and pressure--conditions that can cause an acute pressure sore and superficial skin loss. To prevent these burns from occurring, the skin must not be abraded excessively before the final skin preparation solution is applied; the agent should not be allowed to pool and become trapped under the tourniquet or the torso of the patient, and the agent should be allowed to dry before the patient is draped. In our experience, the agent that has been the most effective and the least irritating to the skin during the time it has been used is povidone-iodine.

Adolescent

Paragangliomas of the neck: clinical and pathologic analysis of 116 cases.

Neck tumors developing from the paraganglion system are best called paragangliomas. They may be described further as to site of origin and as to whether they are functioning or nonfunctioning. Review was made of 116 cases in which operation for paraganglioma was performed at the Mayo Clinic. The diagnosis depends upon demonstration of a lateral neck mass, elimination of other causes, and a tumor blush on angiography. Screening tests should be done to determine whether the tumor is producing epinephrine. Surgical management should be selective, depending upon the location and involvement of surrounding structures, particularly the carotid artery system. A conservative approach is indicated for those patients whose tumor surrounds the carotid vessels, because the risk of complications is greater than the risk of leaving the tumor in the neck. Conservatism is also indicated for patients in the older age group, because of the slow growth of these tumors and the low incidence of malignancy.

Adolescent

Use of muscular, musculocutaneous and omental flaps to reconstruct difficult defects.

These recently popularized flaps make reconstruction of some difficult defects possible in a single operation, with surprisingly good results. They have significant advantage over free flaps (except, perhaps, in the hands ofa few experts) because the chance of failure is considerably less. We do not propose that these flaps be used instead of local tissue (when available), or instead of split-skin grafting (when an appropriate bed exists). Additionally, in some instances, the use of muscle flaps would result in a significant loss of function. However, in suitable cases their use is a rewarding addition to the peviously available methods reconstruction.

Adult

Experience with subcutaneous mastectomy.

A review of 67 patients who had undergone subcutaneous mastectomy indicates that the procedure should be used with well defined criteria. Both the patient and the surgeon should understand clearly that the procedure does not afford absolute protection against breast cancer. In proper perspective, used in appropriate circumstance, subcutaneous mastectomy is one more tool in the physician's armamentarium against breast disease-- a tool that may offer relief and satisfaction, with only moderate risk of morbidity.

Adult