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Biomedical subjects

G B Hart

Publications and source records attributed to G B Hart.

10 recordsLinked to original sources
PubMed1991

Hyperbaric oxygen therapy for acute smoke inhalation injuries.

Hyperbaric oxygen therapy is an important adjunct in the management of respiratory injuries secondary to smoke inhalation, especially when injury is complicated by inhalation of a toxic chemical such as carbon monoxide or cyanide. For carbon monoxide poisoning, such therapy has become a standard of practice. As more information becomes available concerning the ability of hyperbaric oxygen to reduce reperfusion injuries, we anticipate that this therapy will become a standard of practice for managing smoke inhalation injuries and cyanide poisoning as well.

Antidotes↗
PubMed1979

Tissue gas and blood analyses of human subjects breathing 80% argon and 20% oxygen.

Eight human volunteers, individually studied in a hyperbaric chamber, breathed: 1) air at 1 ATA; 2) 80% argon and 20% oxygen and 1 ATA for 30 min; 3) air at 1 ATA for 30 min; 4) 100% 02 at 1 ATA for 30 min; 5) air at 1 ATA for 30 min; 6) 100% O2 at 2 ATA for 60 min; and 7) 80% argon and 20% oxygen at 1 ATA for 30 min. Oxygen, carbon dioxide, nitrogen, and argon tensions were measured in muscle and subcutaneous tissue by mass spectroscopic analyses. Venous blood obtained at regular intervals was analyzed for coagulation and fibrinolytic factors. Inert gas narcosis was not observed. After breathing argon for 30 min, muscle argon tensions were almost three times subcutaneous tensions. Argon wash-in mirrored nitrogen wash-out. Argon wash-in and wash-out had no effect on tissue Po2 or Pco2. Coagulation and fibrinolytic changes usually associated with vascular bubbles were absent.

Adult↗
PubMed1977

Hyperbaric oxygen treatment of refractory osteomyelitis.

Of 70 patients with refractory osteomyelitis who received treatment with hyperbaric oxygen, all improved and 63% have remained free of disease. Treatment is supplemental to properly timed surgery and antibiotic therapy.

Adolescent↗
PubMed1976

The treatment of radiation necrosis with hyperbaric oxygen (OHP).

Sixty-nine patients with radiation necrosis were received by the authors from January 1, 1969 through August 1, 1975. The patients were categorized according to site of injury. Full treatment protocol is discussed including local wound care, antibiotic coverage, surgical procedures, and the administration of hyperbaric oxygen. Results indicate that the combination of hyperbaric oxygen, properly timed surgery, and antibiotic therapy has resulted in improvement in all cases of radiation necrosis and full healing in most.

Aged↗
PubMed1976

Screening test for decompression sickness.

The fibrin-fibrinogen degradation products (FDP) tests were studied in 18 patients having a history of illness associated with diving. FDP tests were performed prior to hyperbaric oxygen therapy (OHP). Eight patients were serious neurologic signs had positive FDP tests and required repetitive therapy. Six patients had negative FDP tests with local musculoskeletal complaints and all were asymptomatic following the first OHP treatment. Three patients were found to be suffering from other diseases. These three patients had normal levels of FDP. One patient treated at another facility 3 months earlier and having paraplegia had a positive FDP test. Serious decompression sickness with neurologic complaints appear to have some degree of disseminated intravascular coagulation (DIC) as reflected by the FDP tests. The FDP test appears to be a useful screening test that may be able to delineate therapy.

Adolescent↗
PubMed1975

Osteoradionecrosis of the mandible. Treatment with hyperbaric oxygen.

Hyperbaric oxygen used in the treatment of 14 patients with intractable osteonecrosis of the mandible produced a favorable response in relief of pain, elimination of extraoral draining sinus tracts, the return of osseous union in areas of the abnormal fracture, and the rapid dissolution of sequestrum without suppuration, so that further loss of hard and soft tissue was minimized. This treatment is a more conservative approach in the management of osteoradionecrosis.

Adult↗
PubMed1975

Hyperbaric oxygen treatment of mandibular osteomyelitis in osteopetrosis.

A patient was successfully treated with hyperbaric oxygen for chronic osteomyelitis of the mandible associated with osteopetrosis. This mode of therapy appears to have a definite place in the management of such patients. There was no clinical, radiographic, or laboratory evidence that the osteopetrosis was made worse by the hyperbaric oxygen.

Female↗