The placental morphology in 22 cases of induced abortion performed one to three months after the Seveso disaster is described. In 15 cases no gross histological or ultrastructural alterations were observed. In seven cases there were many prominent microprecipitates beneath the trophoblastic basement membrane at various distances from the fetal capillaries. Intermediate patterns between simple dense bodies, already well known, and complex pluri-stratified giant structures not previously reported have been described. Combined ultrastructural and x-ray investigations (EDAX analysis) have recorded calcium- and iron-related emissions from these structures. The significance of these findings and their possible relationship to dioxin poisoning has been discussed.

Abortion, Therapeutic↗

PubMedDate not supplied

[Study of the retroperitoneal lymphatic spread of müllerian ovarian carcinoma, using lymphography].

From January 1973 to May 1974, 117 patients with ovarian carcinomas were evaluated with lymphography. The tumors were staged and classified histopathologically according to FIGO (1971). Considering all cases, lymphography showed nodal metastases in 44 patients (38%). Lymphography was positive in 36% of serous cystoadenocarcinomas, in 26% of mucinous cystoadenocarcinomas, in 15% of endometrioid carcinomas and in 36% of unclassified carcinomas. Of the 10 cases not identified by cell type, lymphography was positive in 40% of cases. In 68% of cases bilateral involvement was found. The site of metastatic nodes was in 32% of cases only in the iliac chains were both involved. Considering the single node chains we found 36% of para-aortic, 27% of common iliac, 35% of external iliac and 2% of inguinal involvement. Metastases were observed, regardless of histological type, in 25% of cases in stage III, 62% iin stage IV, 54% in recurrences and only in 5% of cases in stage I. Therefore the lymphatic spread seems to occur in more advanced stages and in recurrences. In 28 of 117 patients node biopsy was performed. Histological-lymphographic correlation was correct in 7/7 positive cases and in 19/21 negative cases (93%). These results show that lymphography is a reliable tool in the evaluation of ovarian cancer.

Adenocarcinoma↗

PubMedDate not supplied

[Organization ofthe delivery room: the minimum requirements].

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Delivery, Obstetric↗