[Functional exploration of the enterochromaffin system].
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Biomedical subjects
Publications and source records attributed to G Aureli.
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The antibacterial activity in vitro of Imipenem (N-formimidoyl-thienamycin) was studied on 237 recently-isolated nosocomial bacterial strains and compared with Aztreonam, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Amikacin and Netilmicin through the determination of susceptibility by the Kirby-Bauer method. Taking into account that 65% bacterial strains, out of the examined ones, came from antibiotic high-pressure departments (45% from bone-marrow transplanted patients in the Hematological Department and 20% from Intensive Care Unit patients), the results obtained in vitro show an activity of Imipenem on Gram-negative bacteria as much as a 92.7% susceptibility and a 75.7% on Gram-positive bacteria; when compared with the activity of the other antibiotics, Imipenem shows a really excellent activity.
We analysed, in the period 1984-1986, the serum of 1733 pregnant women. The relation between the positivities and some probable factors of risk, alimentary habits and touch with tame animals has had valued by statistical method. The analysis shows no increase of risk in the group used to eat underdone meats compared with the group in touch tame animals.
The concentrations of the IgG and IgM fractions have been determined on thirty whole sera and after treatment with protein A, or after chromatographic separation. The analysis of the differences has been effected with Student's t test. No statistically significant differences have been noted between the two methods of separation as far as IgM fraction is concerned, but, on the contrary, significant differences are present for the separation of IgG fraction.
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A microbiological method for the determination of residual antibiotic activity in CSF is described. This disc-diffusion method, utilizing Bacillus stearotermophilus as test organism, is highly sensitive for many antibiotics, including those crossing the blood-brain barrier.