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Biomedical subjects

G Assal

Publications and source records attributed to G Assal.

At least 91 records · Page 5Linked to original sources

[Isolation syndrome of the language area. Neuropsychologic and pathologic study].

A 60 year-old patient in whom spontaneous language was abolished still had a marked capacity for completing phrases and an irrepressible echolalia. From a formal point of view, linguistic ability remained at a high level. Auditory verbal comprehension was severely affected, but was not completely abolished. There was occipital blindness. Pathologic examination reveated extensive bilateral lesions in the regions supplied by the anterior and posterior cerebral arteries. Bilateral destruction of the supplementary motor areas was noted, but the perisylvian language areas were intact. These disorders constitute a syndrome of isolation of language areas which can be used to study anatomical correlations and particularly the role of the supplementary motor area in linguistic and paralinguistic processes.

Akinetic Mutism↗

[No, I am not paralyzed, it's my husband's hand].

A clinical observation is reported and gives the opportunity to discuss such notions as anosognosia, hemiasomatognosia, phantom limb, somatoparaphrenia... Considering cerebral asymmetry right hemispheric lesions could bring a feeling of strangeness in the living. This would result in a delusional elaboration then under left hemispheric control.

Aged↗

[Agraphia and preservation of music writing in a bilingual piano teacher].

A bilingual virtuoso piano teacher developed aphasia and amusia, probably due to cerebral embolism. The perfectly demarcated and unique lesion was located in the left posterior temporoparietal region. Language examinations in French and Italian demonstrated entirely comparable difficulties in both languages. The linguistic course was favorable after a period of auditory agnosia and global aphasia. Language became fluent again 3 months after the onset, with a marked vocabulary loss and phonemic paraphasias with attempts at self-correction. Repetition was altered markedly with a deficit in auditory comprehension but no remaining elements of auditory agnosia. Reading was possible, but with some difficulty and total agraphia and acalculia persisted. Musical ability was better conserved, particularly with respect to repetition and above all to writing, the sparing of the latter constituting a fairly uncommon dissociation in relation to agraphia. Findings are discussed in relation to data in the literature concerning hemispheric participation in various musical tasks.

Agraphia↗

Dissociation of ear preference in monaural word and voice recognition.

The ambiguity in the literature concerning cerebral dominance for voice recognition, has been investigated with a monaural go-no go task, using male and female voices. A left ear advantage for the male, and a right ear advantage for the female voice was found, suggesting that both hemispheres can perform voice recognition. A monaural word recognition test showed the expected left hemisphere dominance.

Adult↗

[Neuropsychological study of crossed aphasia with jargon agraphia].

A case of jargon writing following a right vascular cortico-subcortical lesion in the right sylvian territory of a strictly right-handed patient is presented and analyzed. In spontaneous writings the general graphic form of sentences is present (blanks, punctuation) but a great number of neologisms appear. Disorganisation of oral language in this case of crossed aphasia takes the form of a conduction aphasia. The patient is capable of oral spelling and of writing single letters under dictation. If he is asked to spell orally a dictated word while attempting to write it, his writing is much improved. This observation is contrasted with that of an agraphic patient whose writing is limited to concrete nouns. The analysis of the data obtained confirms the existence of different strategies of graphic encoding recently described in various neuropsychological studies: the agraphia of the crossed aphasic patient is related to the lexical form, that of the second patient is related to the phonological form.

Agraphia↗

Crossed aphasia in a right-handed patient. Postmortem findings.

A right-handed man with a global aphasia and a left hemiparesis was examined after a cerebrovascular accident. Three weeks later, oral language was only mildly impaired but writing disorders were still severe. At autopsy, there was an infarction of the territory supplied by the right middle cerebral artery. There was no lesion in the left hemisphere.

Aphasia↗

[Cerebral amyloid angiopathy. A clinicopathological study (author's transl)].

A case with repeated cerebral hemorrhages associated with severe cerebral amyloid angiopathy (CAA) is reported. CAA may be considered a rare but important cause of cerebral hemorrhages and of local cerebrovascular lesions in the aged. The morphological and ultrastructural characteristics of CAA are discussed. The etiology is still unknown; probably more than one mechanism may be involved.

Aged↗