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Biomedical subjects

G Anders

Publications and source records attributed to G Anders.

At least 37 records · Page 2Linked to original sources

[Comparative studies of the diagnosis of acute myocardial ischemia using radioisotopes].

It is reported on 152 patients with ischaemic heart disease who were examined with technetium-99m-diphosphonate. For clearing up the diagnosis of an acute myocardial infarction the findings of 23 patients with acute myocardial infarction in the course of the disease were compared with clinical and paraclinical parameters such as ECG, ferments and echocardiogram. In these cases could be stated: the Tc-99m-diphosphonate-scintigraphy is a sensitive indicator for a myocardial disease, but is not specific for the diagnosis of an acute myocardial infarction. Other clinical and paraclinical parameters cannot be substituted by the scintigraphy. It contributes to the judgment of the prognosis after an acute myocardial infarction and refers to possible disturbances of the kinetics of the wall. In the acute phase in a clinically ascertained infarction the examination can be renounced.

Adult↗

[Early recognition and functional treatment of hip dysplasia and dislocation].

After a brief introduction the author reports on the examination of hips in newborns and infants, dealing in particular with the "snap phenomenon" and von Rosen's success in Sweden. Ortolani's examination is described and conflicting opinions on radiological examination during the first weeks of life are discussed. Radiation doses measured by various authors are cited. In accordance with established practice in many countries, early treatment (in addition to early diagnosis) is recommended. In this context it is pointed out hat according to various authors, and also in the opinion of the author, inhibited abduction plays a major causal role in necrosis of the head of the femur. Inhibition of abduction should not be corrected by "brusque" treatment, since in the author's opinion this increases the incidence of head necrosis. It seems desirable to perform two preventive examinations of the newborn prior to discharge from the obstetric clinic; the first examination should take place during the first three to four days after birth. It would also seem desirable for the examination to be carried out conjointly by a pediatrician and an orthopedist. Since this is likely to remain a fond hope for the immediate future, the method practiced in Sweden is recommended. Since pediatricians usually perform preventive examinations in Germany, they should be made aware of the importance of the examination technique and of the desirability of consulting an orthopedic surgeon if findings are pathologic. Only close cooperation between pediatrician (or GP) and orthopedist can ensure a satisfactory result for all concerned. Apodietic demands should not be made.

Female↗

[Follow-up results of adduction-derotation osteotomies in hip dysplasia].

The first part of the investigation was concerned with the evaluation of radiographs of 64 children in whom 97 intertrochanteric adduction-derotation osteotomies were performed when the patients were between two and ten years old. Prior to surgery, immediately thereafter and two and six years later, the CCD, AC, ACM and CE angles of all the patients were measured on plain pelvic radiographs. On the radiographs made after six years 70% of the CCD angles were normal, while pathologic coxa valga was found in 15% and coxa vara also in 15%. The AC angle was normal in 32% , the ACM angle in 31%; however, these normal groups were only 76% identical. The CE angle had normalized in 32% of the cases. The second part of the paper deals with clinical and radiological follow-up findings in 46 of these patients in whom 64 hips had been treated. The follow-up period varied between six and 13 years. On clinical examination the result was found to be satisfactory in 59% and unsatisfactory in 41%. A comparison with radiological-anatomical findings showed that in 32% of the radiologically satisfactory cases there were some considerable functional limitations and subjective complaints. The author's own results are compared with communications in the literature, in particular with the Swiss collective statistics published by Jani (1973) and Reichelt and Hansen's publication (1975). To provide the reader with a survey of the number of cases, age at operation and periods of observation quoted by different authors, these data are presented synoptically in tabular form. Another table lists the criteria investigated by the individual authors (AC, ACM, CE, CCD and AT angles). The discussion is completed with conclusions relevant to clinical practice.

Child↗

[Stenosis of the lumber spine. Clinical picture, diagnosis, treatment (author's transl)].

Disc herniation is the most common reason for sciatica followed by osseous entrapment syndromes of the cauda equina. The osseous entrapment of nervous structures is possible within 3 segments of the spinal canal, the center, the recess and the intervertebral foramen. In all cases there is a disproportion of the size of the nervous structures and osseous gliding space. Central lumbar spinal stenosis is associated in 70% with limping (neurogenic claudication) which is often misinterpreted as vascular claudication. Clinic, diagnosis, therapy of lumbar spinal stenosis is described.

Adult↗

[Experiences in implementing a dynamically oriented group therapy in myocardial infarct patients and their spouses].

It is reported on the performance of dynamically orientated group talks with 5 patients with myocardial infarction and their wives within the psychic rehabilitation in phase II. 30 group meetings of a duration of 2 hours each were performed in the outpatient department in a weekly rhythm. At the beginning the implementation of a relaxation method, the autogenic training, for furthering the motivation of the patient for an independent elaboration of the problem in the group as well as for reducing the inability to relaxation often existing in patients with myocardial infarction proved to be favourable. Before the beginning and after the end of the group talks psychodiagnostic tests were carried out. Though scarcely significant differences were the results in the test values, the course of the group talks is to be estimated as successful. The aim reflexion and analysis especially of the interactions between the partners could be obtained after a relatively long initial phase. Conclusions were made for further work in this field.

Acute Disease↗

[Chondroplasia punctata (author's transl)].

The rare condition of chondroplasia punctata is illustrated by two patients. The very different manifestation and course of the disease in these two patients confirms Spranger et al's (1971) view that it is an heterogeneous disease which can be divided into two types. The rhizomelic type is characterised by well marked punctate cartilage calcification, shortening of the extremities, deformities of the metaphyses and epiphyses, frequent cataracts and a fatal outcome. In the Conradi-Hünermann-type the changes are less marked and the patients may survive. In order to classify the disease correctly, radiological examination in early childhood is desirable.

Calcinosis↗

[Development of ossification centers in childhood. A supplement to diagnosis and therapy (author's transl)].

The development of ossification centers in the region of the knee, the head of the femur, in the hand and the ossification of the iliac apophyses is of great significance in childhood. Timely or delayed appearance of the distal femoral and proximal tibial epiphyseal centers is an aid to confirming the diagnosis of a neonatal hypothyrosis. The normal range of variation of the appearance of the center in the head of the femur is therefore important to avoid unnecessary treatment when other parameters of hip dysplasia are lacking. Excessive growth in length, prospective calculation in differences in leg length and therapeutic measures for scoliosis are indications for the determination of the bone age.

Age Determination by Skeleton↗

[Experience with temporary epiphyseodesis after Blount (author's transl)].

The article reports on the results of follow-up esaminations of 57 children in whom temporary epiphysiodesis according to Blount had been performed on account of differences in leg length and because of angular deformities. Numerous complications were revealed during the evaluation of the results, which had to be subdivided into pure clasp complications such as fracture of the clasps, and secondary consequences. Formation of a genu recurvatum was particularly frequent, as well as the development of genu valgum and varum, ligamental insufficiencies, and ugly scars. Although in some cases the preoperatively existing average length was difference 31 mm only, the desired equalisation could not be completely achieved. The article discusses the authors' own errors which contributed to the failures, and lists the results of other authors who had observed similar complications. On the whole, basing on the authors' own experience and on the reports available from other hospitals, it is concluded that temporary epiphysiodesis after Blount should be performed in few exceptional cases only, observing all precautionary measures, if equalisation of differences in leg length is the actual aim of the procedure. However, it is also concluded that the method is suitable for treating relatively pronounced axis deviations provided the children are subjected to regular and reliable post-operative followups.

Adolescent↗

["Physiological" healing and development of coxa valga in congenital dislocation of the hip (author's transl)].

At the University Orthopaedic Clinic Bonn, congenital dislocation of the hip has been treated since 1969, using the Hanausek-Apparatus. In this study the results of "physiological healing" and the development of coxa valga are compared with the results of our previous combined treatment regimen (traction in extension, followed by manual reduction, and initially fixation in the Lorenz position in plaster of Paris and then in Lange position). The term "physiological healing" is explained. The diagnosis coxa valga was made using the criteria of the DGOT working party on hip dysplasias. The problem of femoral head necroses is not considered; this has been reported previously. From this study we see a definite advantage of the functional treatment over the combined method. The "physiological healing" rate was substantially higher, and the development of coxa valga greatly reduced. The clinical results are further supported by animal studies from several authors.

Braces↗

Limits of accuracy obtainable in the direct determination by fluorimetry of fluorescent whitening agents on thin layer chromatograms.

The quantitative direct determination of fluorescent whitening agents (FWAs) by thin layer chromatography involves limits of detection of 0.001 to 0.0005 mug. Visual assessment is about ten to a hundred times less sensitive than photometric measurement on thin layer chromatograms. The standard deviations in 10 measurements of two substances with different degrees of light sensitivity for a single measurement with a limit of detection of the order of 0.005 mug were about +/-13% to 44%. In the higher concentrations normally used (0.5 mug), the standard deviations were only +/-5% for both substances.

Chromatography, Thin Layer↗

Limits of accuracy obtainable in the direct determination by fluorimetry of fluorescent whitening agents in solution.

In direct determination by fluorimetry the limits of detection are governed by the restricted light stability of fluorescent whitening agents (FWAs) in solution. The initial value of a fluorimetric reading can be registered by a rapid recorder, and in this way very light sensitive traces of FWAs as low as 10 parts per thousand million can be measured be measured with a statistical standard deviation of +/-15% for a single measurement and a reproducibility of +/-50% with a statistical certainty of 99%.

Benzoxazoles↗