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Biomedical subjects

G Anania

Publications and source records attributed to G Anania.

At least 37 records · Page 2Linked to original sources
PubMed1993

[The use of automatic devices for ultrasonography-guided histologic biopsy of breast lesions].

The authors report their experience with the use of biopsy guns for the histologic sampling of breast lesions. Cytologic sampling by means of FNAB has been preferred so far because it was thought to be simpler, less risky and more reliable. Nevertheless, cytologic sampling exhibits several drawbacks--e.g., the need of repeated punctures to get sufficient cell material, frequent problems in diagnosing benign lesions and the decisive influence of the operator's skills. The use of biopsy guns for histologic sampling solves the above problems, because the value of the sample is not affected by the operator's skills; moreover, fewer punctures are needed and their value does not depend on lesion nature. Our series of cases includes 65 patients who underwent histologic sampling for suspected lesions over 10 months. A hundred and seventy-two samples were collected and 77 lesions were diagnosed, 47 of them malignant and 30 benign (fibroadenomas, fibrocystic changes, epitheliosis). Sensitivity, specificity and diagnostic accuracy of the method were 93.6%, 100% and 96.1%, respectively, with 6.4% false negative due to 3 cases where the lesion was not centred due to misguidance.

Adult↗
PubMed1992

[An aneurysm of the extracranial carotid. A report of an interesting clinical case].

One case of extracranial carotid artery aneurysm observed is reported. This uncommon and interesting vascular disorder is still under discussion even if the present tendency is to treat it actively by reconstructive surgical procedures that make it possible to avoid the natural aneurysm complications with a low risk of postoperative neurological lesions.

Aged↗
PubMed1991

[Aplasia of the internal carotid. A clinical case report].

Among the anomalies of internal carotid artery, agenesis and aplasia recur with a low rate: only about sixty cases are reported in literature. We observed a case of aplasia of the left internal carotid in a 49 year old male suffering from hypertension and showing cerebro-vascular symptoms due to TSA pathology: it was studied with arterial angiography and duplex scanner. The angiographic examination raised a suspicion of left internal carotid thrombosis; on the contrary the duplex scanner revealed a correct diagnosis of carotid aplasia.

Angiography, Digital Subtraction↗
PubMed1990

[Qualitative ultrasound analysis as a preliminary step in revascularization of the femoro-popliteal axis].

The Authors report on the use of non-invasive techniques in the preliminary evaluation of revascularization of the femoral-popliteal axis. The study of this pathology, for which surgery has become less and less frequent, being limited to the more serious cases, has greatly benefited by the use of H/R echography and of Doppler. These techniques, which remain complementary to angiography, have proved very important and reliable for their capacity to visualize the arterial lumen, an important element for the pre- and post surgical evaluation of vascular recanalization and of the relationship of continuity and continuity with the nearby structures.

Angiography↗
PubMed1990

[Isthmic coarctation of the aorta. Description of an anomalous case].

An anomalous (because of the advanced age of its onset) case of isthmic coarctation of the aorta in preductal site observed at the persistence of hypertensive symptomatology associated with cephalgic and lipothymic attacks is reported. Instrumental examinations confirmed the clinical suspicion and resective-reconstructive surgical treatment led to complete resolution of both cause and effect.

Adult↗
PubMedDate not supplied

[Current trends and therapeutic strategies in breast carcinoma. Introduction].

Carcinoma of the breast is a pathology of great social interest for its increase in occurrence and because it is leading cause of tumor-induced death among women in Western Countries. There have been continual changes in the understanding of biological implications of the tumor and in the ensuing therapeutic approaches. Breast cancer is currently viewed as a systemic disorder right from is outset varies widely in behavior within the same histologic type. Hence, the need for a multidisciplinary approach where locoregional treatment (surgery and radiotherapy) is accompanied by systemic (chemotherapy and hormone therapy). As to surgery, there has been a shift away from the radical to the conservative approach which avoids functional and above all psychological mutilation. Beside always being carried out when surgery is not radical, radiotherapy depends on the stage of the tumor. As to chemotherapy, while there is sound evidence proving it to be useful in postoperative adjuvant treatment, its usefulness in preoperative treatment still remains to be demonstrated. Future studies will have to identify new morphobiological parameters of the tumor capable of predicting the clinical behavior and response to therapy of the various types of breast cancer so as to correctly standardize therapeutic actions and their aiming.

Antineoplastic Agents↗
PubMedDate not supplied

Subcutaneous right leg metastasis from rectal adenocarcinoma without visceral involvement.

The occurrence of cutaneous metastasis from colorectal cancer is rare, with a reported frequency of less than 4 to 5 percent. Typically signifies widespread disease and a poor prognosis. Metastases from adenocarcinoma of the colon-rectum usually occur within two years of resection of the primary tumour, and the average survival of a patient with cutaneous metastasis has been reported as ranging from 3 to 18 months. The case reported here concerns a patient who developed a skin metastasis without evidence of visceral involvement after treatment of rectal carcinoma. It is advisable to implement cutaneous biopsy in patients with a history of carcinoma; this may establish the diagnosis of metastatic disease and change the methods of therapeutic intervention and prognosis.

Adenocarcinoma↗
PubMedDate not supplied

[Role of surgery in the treatment of primary gastric lymphoma and assessment of new therapeutic approaches].

Controversy remains regarding the best treatment for primary gastric lymphoma (PGL). Recent developments in diagnosis and chemotherapy have changed strategies for this disease. Fourteen patients with primary gastric non-Hodgkin's lymphoma underwent surgery. Before surgery 9/14 patients underwent Helicobacter pylori eradication, and 4/14 were treated with chemotherapy. In two patients chemotherapy was not possible because of risk of perforation recurred. Total gastrectomy with N2 lymphadenectomy, splenectomy, biopsy of mesenteric lymph nodes, and hepatic biopsy were done. Then patients underwent post-operative chemotherapy. Involved-field radiation therapy was made in four patients. The overall survival was 64.2 percent. Surgery was the treatment of choice in cases of gastric lymphoma non-responsive to medical therapy and to control complications or when gastroscopy did not supply correct diagnosis.

Female↗
PubMedDate not supplied

[Chemotherapeutic prophylaxis in the preparation of the large intestine for surgical interventions: rifaximin P.O. vs. cephalosporin I.V].

30 patients were examined: 17 males and 13 females aged between 53 and 83 years (average age 66 years), candidates for large intestine surgery. For 5 days before the operation, they were treated at random, in a balanced way, with cefotaxime (3 g/day intravenously), either alone or associated with rifaximin (1200 mg/day P.O.). Rifaximin, an antibiotic drug endowed with a topical intestinal action, substantially increased the antibacterial activity of the well known and traditional third-generation cephalosporins therapy in the prevention of bacterial infections after major colic surgery. Intestinal bacterial load and pathogenic micro-organisms reduction was substantially increased. Furthermore, a more limited onset of post- surgical complications was observed, together with a better post-surgical clinical course, and a more rapid recovery of normal intestinal functions. The possibility of carrying out an effective chemoprophylaxis by means of an oral drug, such as rifaximin, must be encouraged as, among other things, it substantially reduces the intolerance risk at systemic level, which is nevertheless possible with parenteral antibiotic treatments.

Administration, Oral↗
PubMedDate not supplied

Seasonal variation in onset of acute appendicitis.

PURPOSE: Several acute diseases exhibit a circannual pattern. The present study was aimed to verify the possible existence of a seasonal variability in the onset of acute appendicitis (AA). PATIENTS AND METHODS: All cases of AA diagnosed at the St Anna Hospital of Ferrara, Italy, from 1998 to 2004, were considered. The total sample was divided into subgroups by gender, age (< or = 19 and > or = 20 years), and ICD9-CM code. For statistical analysis, the distribution of symptom onset was tested for uniformity by the chi2 test for goodness of fit, and chronobiological analysis was performed by applying partial Fourier series. RESULTS: In the 7-year period analysis, 1331 consecutive cases of AA (673 males) were observed. The analysis showed, for total population, a seasonal variation with a peak in summer and a nadir in spring. Subjects < or = 19 years (n = 654) showed a higher frequency of events in winter (winter = 191 cases, 29.2%; spring = 154 cases, 23.5%, summer = 142 cases, 21.7%, autumn = 167 cases, 25.5%, chi2 = 8.07 p = 0.046), whereas subjects > or = 20 years (n = 677) showed a higher frequency in summer (winter = 150, 22.2%, spring = 151, 22.3%, summer = 214, 31.6%, autumn = 162, 23.9%, chi2 = 16.33 p = 0.001; difference between the two groups: chi2: 19.2, p < 0.001). Cases of AA with peritonitis (ICD-9 540.0, n = 90), were more frequent in summer (winter = 18, 20%, spring = 19, 21.17%, summer = 38, 42.2%, autumn = 15, 16.7%, chi2 = 14.22, p = 0.002), and chronobiological analysis found a statistically significant peak of higher incidence in July (PR 68.2, 95%CL: May-September, p = 0.006). CONCLUSIONS: The existence of a seasonal pattern in the onset of AA is confirmed, with differences in relation to age.

Acute Disease↗
PubMedDate not supplied

[Tumors of the carotid glomus (chemodectomas)].

Two cases of carotid body tumor (chemodectomas) have been reported and at this regard the international literature reviewed. Concerning the diagnosis selective angiograms represent the investigation of choice in clinical assessment and planning operative approach. Doppler-ultrasound results particularly useful in the follow up of patients after surgery. With advances in vascular technique, complete excision of the tumor has become possible and is now associated with minimal morbidity and mortality. Survival rate of resected patients is equivalent to that for sex age matched control subjects.

Carotid Body Tumor↗
PubMedDate not supplied

Simultaneous pancreas kidney transplantation: initial experience of the Emory University transplant service.

The successful replacement of islet tissue by pancreas transplantation appears to be beneficial in the early course of those uremic diabetic recipients who receive a simultaneous renal transplant. The long-term advantages of SKP transplantation remain to be determined, however, current improvement in patient and graft survival following SPK and the difficulties thus far reported in islet cell transplantation have renewed clinical interests in SPK, PAK and PA transplantation. In our experience, pancreas transplantation has been a challenging technical, immunological and physiological endeavor which was well received by our patients despite the initial problems and complications we and they encountered. Notwithstanding extensive preparation, our team experienced a "learning curve" and we present many of the lessons we learned. This knowledge has aided our transplant team in the successful management and avoidance of these complications and other inherent problems associated with SKP transplantation in subsequent patients.

Anastomosis, Surgical↗
PubMedDate not supplied

[Benign schwannoma of the celiac tripod simulating a pancreatic neoplasm].

The authors present a rare case of benign retroperitoneal schwannoma; initially diagnosed as a neoplasm of the pancreas. A comprehensive review of the literature is employed to focus on the main problems involved in the management of this disease: difficulty in formulating a diagnosis, due to the non-specific nature of clinical manifestations; and difficulty in formulating a prognosis, because of the lack of criteria available for distinguishing benign from malignant forms.

Aged↗
PubMedDate not supplied

[Trans-umbilical cholecystectomy: a new laparoscopic cholecystectomy technique. Description of the technique and preliminary results].

The aim of videolaparo-cholecystectomy is to achieve a good results with minimal surgical trauma. Recently there has been an evolution of this technique toward the progressive reduction of trauma with an improvement of the results, also from the aesthetical point of view. In this article we describe our new videolaparo-cholecystectomy technique. Trans-umbilical videolaparo-cholecystectomy represents a variant of the traditional technique. This new method allows the operation to perform with only two trocars positioned in the peritoneum cavity through only one umbilical incision. The technical innovation of this method consists of the substitution of the others trocars, utilized in the traditional technique, with an equal number of trans-parietal suspension wires. Up to now, we have given 95 patients this kind of operation being successful in 67% of the cases. We think that this new technique, requiring as it does only standard laparoscopic instruments, is in accordance with the philosophy of mini-invasive surgery. The suspension wires are responsible for minimal bile spreading which is not an important complication if the surgeon performs an accurate and through cleaning of the abdominal cavity at the end of the surgical procedure. The patient better accepts this technique because of its better aesthetical results. In spite of this there should be more evaluable data about trans-umbilical videolaparo-cholecystectomy especially about the incidence of post-operatory complications.

Cholecystectomy, Laparoscopic↗