Search PubMed⌕ Search

Biomedical subjects

G A do Pico

Publications and source records attributed to G A do Pico.

6 recordsLinked to original sources
PubMed1996

Lung (agricultural/rural).

Industrialization of farming, animal raising, and forestry has added chemical and mechanical hazards that need to be recognized and prevented. Lung disease among farmworkers can result from a wide variety of hazardous exposures, which include organic dusts, allergens, chemicals, toxic gases, and infectious agents. In addition to nonspecific symptoms of mucous membrane irritation, farmworkers can experience occupational asthma or bronchitis, organic dust toxic syndrome, hypersensitivity pneumonitis, silo filler's disease (toxic hemorrhagic pulmonary edema), and neuromuscular respiratory failure. At risk are farmworkers and those involved in the processing, stocking, transportation, handling, and inspection of unprocessed agricultural, animal, and forestry products; veterinarians; gardeners; game, river, and forest keepers; persons involved in building, supplying, or servicing farm operations; and residents of rural communities. Worker education on the risks of environmental exposures, adherence to safety regulations, and increased knowledge of the cause and prevention of environmental diseases will reduce their prevalence and their adverse human and animal health and socioeconomic effects.

Agriculture↗
PubMed1995

Was the Bishop right?

Explore the source record for details and available documents.

Bronchial Provocation Tests↗
PubMed1995

Toxic gas inhalation.

Severe toxic fume inhalations, usually accidental due to human error or equipment failure, can result in immediate death from asphyxia or cause mild to severe respiratory distress from acute upper airways inflammation, delayed pulmonary edema, respiratory muscle dysfunction, or a combination of illnesses. Most patients are expected to survive and recover with little or no residual dysfunction regardless of the severity of the initial event. However, in some cases disabling long-term sequelae, eg, bronchiectasis, chronic airflow obstruction, bronchial hyperreactivity, asthma-like disease (reactive airways dysfunction syndrome), bronchiolitis obliterans, or residual psychophysiologic dyspnea, can occur. Therapy of the respiratory effects of irritant gases should follow the general principles used for the treatment of upper and lower airway obstruction, noncardiogenic pulmonary edema, and hemorrhagic pneumonitis while spontaneous healing and recovery occurs, because no specific therapy is available for direct chemical pulmonary injury. Corticosteroids are frequently used and recommended, but their efficacy in altering the course and outcome of respiratory injury has not yet been properly documented.

Environmental Exposure↗
PubMed1992

Hazardous exposure and lung disease among farm workers.

Industrialization of farming, animal raising, and forestry has added new chemical and mechanical hazards that need to be recognized and prevented. Lung disease among farm workers can result from a wide variety of hazardous exposures that include organic dusts, chemicals, and toxic gases. In addition to nonspecific symptoms of mucous membrane irritation, farm workers can develop occupational asthma or bronchitis, organic dust toxic syndrome, hypersensitivity pneumonitis, silo filler's disease (toxic hemorrhagic pulmonary edema), and neuromuscular respiratory failure.

Agricultural Workers' Diseases↗
PubMed1979

Pulmonary reaction to upper mantle radiation therapy for Hodgkin's disease.

To study the effects of upper mantle radiation therapy on pulmonary function, forced expiratory volume in one second (FEV1), vital capacity (VC), inspiratory capacity (IC), diffusing capacity for CO (DLCO) and diffusion per unit of alveolar volume (DL/VA were determined in 28 patients with Hodgkin's disease, stages 1--3, before therapy and at regular intervals thereafter. Within the first year of follow-up there were significant declines in DLCO, VC, and IC, whereas there were no significant changes in FEV1 or DL/VA. DLCO showed the greatest decline in the largest number of subjects (22/28). Eleven of the 22 had 20 to 60 percent decline of DLCO from baseline. The maximum mean decline in DLCO was -12.7 +/- 3 percent at the 87th +/- 3 days from initiation of therapy postradiation sustained through the 150th day and improving to pretreatment value (+/- 5 percent) by the 8th to 12th month. The changes in DLCO seemed to be independent of the radiation dose ranges evaluated, clinically apparent intrathoracic lymphoma, postradiation radiographic abnormalities and respiratory symptoms. We concluded that impairment in diffusing capacity and loss of vital capacity will develop in most patients receiving upper mantle radiation therapy, indicating that pulmonary reaction occurs despite lung shielding. The functional losses were prolonged and occasionally severe, but were transient and subclinical in most but not all cases. A case of fatal radiation pneumonitis affecting the lung beyond the field of irradiation is reported.

Adolescent↗