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Biomedical subjects

G A Stepanov

Publications and source records attributed to G A Stepanov.

At least 19 recordsLinked to original sources

Human fetal neural stem cells in rat brain: effects of preculturing and transplantation.

The fate of human fetal stem/progenitor cells transplanted into rat brain depends on conditions of preculturing (long or short) and state and site of transplantation. Human nestin-positive stem cells cultured according to the short protocol did not migrate into hypoxic and normal brain after transplantation, but actively migrated in damaged spinal cord. After transplantation of long-cultured cells into the brain mainly committed neuroblasts and solitary nestin-positive cells migrated from the site of transplantation into the brain.

Animals↗

Immunohistochemical study of fetal stem/progenitor cells from human brain transplanted into traumatized spinal cord of adult rats.

Neural stem/progenitor cells from human fetal brain were grown in a tissue culture and transplanted into traumatized spinal cord of adult rats. The behavior and differentiation of transplanted cells were studied morphologically by means of histological and immunohistochemical methods and confocal microscopy. Human neural stem/progenitor cells were viable for not less than 3 months. They migrated and differentiated into neurons and glia in the traumatized spinal cord of adult rats.

Animals↗

[Methods of detection and characteristics of clinical manifestations of tuberculosis in children and adolescents].

Methods of detection of tuberculous infection in 127 children and adolescents treated in special hospitals and sanatoria have seen analyzed. The diagnosis was made using tuberculin in 62.2%, epidemiological evidence in 12.6%, fluorographic findings in 7.8%, survey of risk groups in 7.1%. 10.2% of the patients sought medical advice. A favourable course of the disease was seen in cases detected at tuberculin diagnosis and risk group examination. Complications occurred primarily in those who sought medical advice.

Adolescent↗

[Use of the human umbilical vein in arterial surgery of the lower extremities].

The article presents results of using the human umbilical vein for plasty of lower extremity arteries. There were 44 operations on 43 patients. In 22 cases the prosthesis of the umbilical vein was used for the femoro-popliteal shunts and in 22 cases for femoro-femoral shunts. In 18 patients the shunts were potent within 6 years of the followup observation which demonstrates good prospects of using the human umbilical vein in reconstructive surgery of the vessels of small and medium diameter.

Adult↗