Biomedical subjects
G A Spiller
Publications and source records attributed to G A Spiller.
Letter: Semisynthetic diets for adult Macaca nemestrina.
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Selected blood values for Macaca nemestrina fed semipurified fiber-free liquid diets.
Selected plasma chemistry and hematologic data were obtained from 8 pig-tailed monkeys fed semipurified fiber-free liquid diets for a prolonged period of time. No significant differences were noted from reported values of pig-tailed monkeys fed solid foods except for a slightly higher level of total plasma protein and globulins.
Letter: Research on dietary fibre.
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Physiological effect and acceptance of various natural foodstuffs in the Pig-Tailed monkey (Macaca nemestrina).
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Development of a semipurified diet for the adult pocket mouse (Perognathus).
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Bulk laxative efficacy of a psyllium seed hydrocolloid and of a mixture of cellulose and pectin.
The cellulose/pectin combination (C/P) investigated in this study is as efficacious as a psyllium seed product widely used as a bulk laxative. Because of its physical characteristics (whiteness, lack of flavor and odor, lack of gelling upon standing), it is easy to use as a component of baked foods, sauces, drinks, stews, and in other recipes. Given its fecal bulking equivalence to the popular psyllium-based products, C/P offers advantages to the patient who takes a bulking agent regularly because of the wide choice of methods of consumption, ensuring better compliance over long periods of time. This cellulose/pectin combination appears to be a viable alternative to the limited choice presently available to the bulk laxative user and could also be used as a plant fiber supplement whenever this is desirable.
Guar gum and plasma cholesterol. Effect of guar gum and an oat fiber source on plasma lipoproteins and cholesterol in hypercholesterolemic adults.
The hypolipidemic effect of guar gum (GG, 15 g/day) was compared with that of an oat fiber source (OFS, 77 g/day). Both treatments supplied the same amount of total dietary fiber (11 g/day) and were taken with water three times a day for 3 weeks at mealtime. Thirteen free-living adult men and women participated in the study. Their total plasma cholesterol (TC) was 244 +/- 21 mg/dl (mean +/- SD), and plasma triglycerides (TGLYs) were 149 +/- 93 mg/dl before the intervention. Diets were monitored to ensure that no changes occurred other than the replacement of carbohydrate calories for the 200 kcal/day supplied by the OFS. Combined averages for both of the crossover phases showed that GG induced a reduction in TC of 26 +/- 10 mg/dl and in low density lipoprotein cholesterol of 25 +/- 9 mg/dl. The OFS induced a reduction in TC of 9 +/- 13 mg/dl and in low density lipoprotein cholesterol of 11 +/- 4 mg/dl. Although both treatments were effective in reducing elevated TC, GG at the levels fed was significantly more effective (p less than 0.001) in reducing TC. Neither treatment induced significant changes in high density lipoprotein cholesterol or very low density lipoprotein cholesterol.