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Biomedical subjects

G A Grigor'eva

Publications and source records attributed to G A Grigor'eva.

At least 19 recordsLinked to original sources
PubMed2005

[Algorithm of diagnosis and treatment of complicated forms of nonspecific ulcerative colitis and Crohn's disease].

AIM: To detect complicated forms of nonspecific ulcerative colitis and Crohn's disease, to calculate treatment algorithm. MATERIAL AND METHODS: The results of a 20-year prospective trial including 313 patients with nonspecific ulcerative colitis (n = 180) and Crohn's disease (n = 133) have been analysed. The following parameters were considered: clinical findings with calculated index of the disease activity, endoscopic, x-ray and morphological data. All the information was processed using computer programs Biostat and Exell 97 Mean and standard deviations were calculated. Chi-square and Fisher's criteria were used. RESULTS: Complicated forms of nonspecific ulcerative colitis and Crohn's disease were detected and characterized. Programs of treatment of complicated forms of intestinal inflammatory diseases and measures for maintenance of the remission are proposed.

Adult↗
PubMed1998

[Genetic control of isolating mechanisms in the genus Drosophila].

Published data on the genetic control of isolating mechanisms in the genus Drosophila are discussed. The main isolation types of genetic mechanisms (ecological isolation, behavioral isolation, hybrid sterility, and the inviability or impaired development of interspecific hybrids) are considered. It is shown that each of the isolation barriers between different species is controlled by a small number of genes. However, as each pair of sibling species is usually separated by several barriers, the total number of isolation genes is about 20 to 30. The probable sequence of events in the appearance of isolation barriers during the divergence of novel species is discussed. A concept of the consolidation of a new species is proposed. This concept is based on the assumption of the genetic determination of behavior that promotes crossing between individuals of the new genotype and constrains their crosses with individuals of the ancestral genotype.

Animals↗
PubMed1994

[Variability of inversion polymorphism in populations of Drosophila lummei, Hackman].

Comparison of inversion polymorphism in Drosophila lummei populations from Finland (Kemi) and Russia (Rybnyi) revealed additional species-specific paracentric inversions in chromosomes 2-4. The newly found inversions, 2V, 3M, 4U, and V, were reported only for the Russian population. The 2U inversion had been earlier detected in D. lummei and in the second chromosome of a D. ezoana population from Kamchatka. Species-specific 5T inversion from the Finland population was not found in the Russian population. 4R, S, and 5S inversions were common for both populations but had different sample frequencies. 4R and 5S inversions were more frequent in the Finland, and 4S in the Russian population which may indicate their different adaptive values in these areas. All inversions except 3M were localized in subterminal chromosome regions. 3M inversion was localized in the submedian region.

Animals↗
PubMed1991

[Non-specific ulcerative colitis and Crohn's disease].

The paper is concerned with current status of nonspecific ulcerative colitis and Crohn's disease. Clinical, diagnostic and therapeutic aspects are considered. Crohn's disease was studied in its variants. Hyperbaric oxygenation introduced in combined treatment of the two diseases is evaluated.

Colitis, Ulcerative↗