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Biomedical subjects

G A Fueredi

Publications and source records attributed to G A Fueredi.

6 recordsLinked to original sources
PubMed1995

The morbidity of heparin therapy after development of pulmonary embolus in patients undergoing thoracolumbar or lumbar spinal fusion.

STUDY DESIGN: The postoperative course of patients who developed a pulmonary embolus after thoracolumbar or lumbar spinal fusion treated with heparin was studied to quantify the morbidity risk of anticoagulation. OBJECTIVE: To compare the morbidity risk of heparinization with that of an alternative form of therapy--inferior vena cava filter placement. SUMMARY OF BACKGROUND DATA: Therapeutic heparinization was the current treatment of choice for patients who develop thromboembolic disease after surgery. Although heparin usage was reported to be associated with a number of complications after other orthopedic and general surgical procedures, no information was available to identify complications of heparinization after lumbar or thoracolumbar spine surgery or to define the risk of such complications. METHODS: Twenty-two members of the Scoliosis Research Society were polled to determine their experiences with the anticoagulation of this subset of patients. Surgeons polled had a combined experience of 250 man-years and had performed more than 13000 thoracolumbar and lumbar spinal fusions. The MEDLINE database was used to review pertinent English language publications describing inferior vena cava filter complications, effectiveness, safety, and indications for use. RESULTS: Nine patients were located who fit the inclusion criteria of this study. Six (67%) had complications attributable to heparinization. Clinically significant complications of filter placement ranged from 0.12% to 10.1%. CONCLUSIONS: Heparinization after the development of pulmonary embolus in patients recently undergoing spinal fusion is associated with a high complication rate. The morbidity of vena cava filter placement is low and should be considered a treatment alternative in the treatment of patients who experience pulmonary embolus after surgery.

Adolescent↗
PubMed1990

Does dysbaric osteonecrosis progress in the absence of further hyperbaric exposure? A 10-year radiologic follow-up of 15 patients.

Progression of dysbaric osteonecrosis of the femoral and humeral heads was evaluated in 15 caisson workers. All patients had dysbaric osteonecrosis but had had no further exposure to hyperbaric pressures for a minimum of 10 years. The original and follow-up radiographs were compared in each case. Of 24 normal articular heads (nine humeral and 15 femoral), one (4%) humeral head developed new subcortical sclerosis. Of the 36 juxta-articular lesions, seven (four humeral and three femoral) showed major changes in the 10-year interval. Of these seven, two (one humeral and one femoral) had new articular fractures and three (two humeral and one femoral) with articular fractures showed progressive osteoarthritis. We conclude that caisson workers can develop lesions in previously normal areas and experience worsening of previously known lesions in the absence of further exposure to hyperbaric pressures.

Aged↗
PubMed1989

Coronary angiography in atrial myxoma: findings in nine cases.

We report the findings on selective coronary angiography in nine patients with atrial myxomas. The angiograms were obtained because the patients were suspected of having coronary artery disease. In each case, the diagnosis of myxoma had been made earlier by echocardiography. Coronary angiography in five (55%) of the nine patients showed neovascularity in the tumor without calcification. In one patient, the angiogram showed a varix of the myocardium at the base of the tumor. The angiograms in three (33%) of the nine patients did not show neovascularity but showed tumoral calcification. Six (67%) of the nine patients had significant coronary artery disease that required coronary artery bypass grafting along with resection of the myxoma. These data suggest that the incidence of neovascularity in atrial myxomas is higher than previously reported. Furthermore, a significant number of this older population presented with operable artery disease as well as atrial myxoma.

Adult↗
PubMed1989

Evaluating EMP with computed tomography.

Extramedullary plasmacytomas (EMP) of the nasopharynx are rarely associated with osseous destruction, and when destruction does occur, only minimal erosions have been found. More extensive bony involvement and intracranial extension in neoplasms of the head and neck usually suggest the presence of a more aggressive tumor such as carcinoma. We report computed tomographic (CT) findings in a nasopharyngeal EMP showing extensive intracranial involvement and severe bony destruction.

Cranial Fossa, Posterior↗
PubMedDate not supplied

MR findings in the brains of compressed-air tunnel workers: relationship to psychometric results.

Cranial MR imaging was performed in 30 subjects who had been involved in compressed-air tunnel projects in and around Milwaukee, WI. Nineteen of these subjects had been exposed to various degrees of hyperbaric air as calculated by an exposure index (average PSI pressure gauge multiplied by the number of years exposed), while 11 of the subjects were age-matched controls who belonged to the same labor union but had not been exposed to hyperbaric air. All MR scanning was done on a 1.5-T unit, and axial, sagittal, and coronal T1, proton density, and T2-weighted images were obtained. Ventricular size was measured objectively. Foci of increased T2 intensity within deep white matter tracts were evaluated as to number and location, and psychometric testing was performed on both groups to exclude preexisting organic brain disease. The 19 subjects in the experimental group had a statistically higher number (p = .05) of white matter lesions (more than 152) than the control group (22 lesions), and 37% of the experimental group had more than 20 white matter lesions each (seven of 19 subjects) while only 18% of the control group had 10 or 11 lesions each. The experimental group had a five times higher risk than the control group of having high-grade lesions, and a high statistical correlation (p = .02) was found between the number and severity of lesions in the experimental group as compared with the control group when linear trend analysis was performed. No correlation was found between exposure index, MR grade or number, or aseptic necrosis. Ventricular size was normal in all subjects.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗