Search PubMed⌕ Search

Biomedical subjects

Frank R Noyes

Publications and source records attributed to Frank R Noyes.

At least 19 recordsLinked to original sources

Posterolateral knee reconstruction with an anatomical bone-patellar tendon-bone reconstruction of the fibular collateral ligament.

BACKGROUND: The authors have long advocated a graft reconstruction of the fibular collateral ligament, believing that direct suture repair or augmentation procedures do not provide a stable construct. PURPOSE: To describe an operative technique and determine the clinical outcome of a bone-patellar tendon-bone graft anatomical replacement of the fibular collateral ligament in a consecutive series of knees. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A consecutive group of knees undergoing anatomical posterolateral reconstruction that included a fibular collateral ligament reconstruction with a bone-patellar tendon-bone graft was prospectively followed to determine the functional outcome and failure rate. Thirteen patients (14 posterolateral reconstructions) were observed 2 to 13.7 years postoperatively. All major posterolateral structures were surgically restored. The procedure represented a primary reconstruction in 7 patients and a revision in 6 patients. Anterior cruciate ligament ruptures were found in 7 patients and bicruciate ruptures in 5 patients, all of which were reconstructed. The rehabilitation protocol allowed immediate knee motion from 0 degrees to 90 degrees but included protection against lateral joint loads to prevent graft stretching and failure. The results were determined by a knee examination, stress radiography, KT-2000 arthrometer, the Cincinnati Knee Rating System, and the International Knee Documentation Committee Rating System. RESULTS: Significant improvements were found at follow-up for pain (P = .0001), swelling (P = .02), patient rating of the overall knee condition (P < .001), walking (P < .05), and stair climbing (P < .05). Thirteen of the 14 (93%) reconstructions restored normal or nearly normal lateral joint opening and external tibial rotation and 1 failed. The anterior cruciate ligament reconstructions were normal or nearly normal in 11 knees and abnormal in 1 knee. CONCLUSIONS: The anatomical posterolateral procedure was effective in restoring normal limits to lateral joint opening and external tibial rotation, allowed immediate knee motion, and appeared to protect other soft tissue repairs.

Adolescent↗

An analysis of the causes of failure in 57 consecutive posterolateral operative procedures.

PURPOSE: To investigate 57 failed posterolateral procedures in 30 consecutive knees to determine factors that may have contributed to the failure. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Thirty patient records were reviewed by an independent surgeon. The index posterolateral operations were done for 13 acute and 17 chronic knee injuries. The anterior cruciate ligament was ruptured in 17 knees, the posterior cruciate ligament was torn in 5 knees, and both cruciates were ruptured in 8 knees. In 25 knees, 46 revision posterolateral procedures had been performed, of which 27 had also failed (in 21 knees). Five knees did not undergo revision of the posterolateral structures. RESULTS: In 22 knees, multiple factors were identified that most likely contributed to the failure of the posterolateral procedures. The most common factors were nonanatomical graft reconstruction (23 knees), untreated varus malalignment (10 knees), and failure to successfully reconstruct all ruptured knee ligaments, including cruciates (27 knees). Thirty-nine anterior cruciate ligament procedures were done in 24 knees, including 24 primary and 15 revision operations. Seventeen posterior cruciate ligament procedures were done in 13 knees, including 13 primary and 4 revision operations. At the time of writing, 16 of 24 knees had a functional anterior cruciate ligament graft and 5 of 13 had a functional posterior cruciate ligament graft. CONCLUSION: The results suggest greater emphasis during the index operation for anatomical graft reconstruction of one or more of the posterolateral structures as necessary, restoration of all ruptured cruciate ligaments, and correction of varus malalignment.

Adolescent↗

Opening wedge high tibial osteotomy: an operative technique and rehabilitation program to decrease complications and promote early union and function.

BACKGROUND: High tibial osteotomy has been associated with significant complications, including delayed union or nonunion, loss of correction, arthrofibrosis, and patella infera. HYPOTHESES: A technique for opening wedge osteotomy that incorporates an autogenous iliac crest bone graft will prevent delayed union or nonunion, allow early rehabilitation and weightbearing, and prevent knee arthrofibrosis and patella infera. Secondly, the authors' methods for calculating the desired correction of valgus alignment prevent undesired alterations in tibial slope. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A total of 55 consecutive patients who underwent high tibial osteotomy were observed at a mean of 20 months postoperatively. Preoperative and postoperative measurements of radiographs were conducted by independent examiners for bony union, tibial slope, and patellar height. The osteotomy opening size ranged from 5 to 17.5 mm; 35 knees (64%) had openings < or =10 mm, and 20 knees (36%) had openings >11 mm. RESULTS: The osteotomy united in all patients. Three patients had a delay in union, which resolved by 6 to 8 months postoperatively. A loss of fixation occurred in 1 patient, who admitted to full weightbearing immediately after surgery; the osteotomy required revision. The iliac crest graft site healed without complications, and there were no infections, loss of knee motion, nerve or arterial injuries, alterations in tibial slope, or cases of patellar infera postoperatively. Full weightbearing was achieved at a mean of 8 weeks (range, 4-11 weeks) postoperatively. CONCLUSIONS: The operative technique including use of an autologous iliac crest bone graft in addition to a progressive rehabilitation program successfully prevented nonunion, change in tibial slope, and knee arthrofibrosis in this study.

Adult↗

Reconstruction of the medial patellofemoral ligament with autologous quadriceps tendon.

In knees with insufficient or previously disrupted medial retinacular and patellofemoral ligaments caused by subluxation or dislocation, anatomic reconstruction of the medial patellofemoral ligament may be performed. This procedure involves harvesting of an 8 x 70-mm medial quadriceps tendon graft, which leaves the quadriceps tendon retinacular attachment intact and avoids patellar and femoral drill holes. This graft is passed beneath the retinaculum adjacent to the femoral epicondyle and is sutured to the medial intermuscular septum-a procedure that reproduces the medial patellofemoral ligament and is supported by imbrication of the remaining medial retinaculum. The tension of the graft and of the medial retinaculum is set at closure with the knee in 30 degrees to 45 degrees of flexion; this allows the patella to be moved a distance equal to 25% of its width. Avoidance of drill holes allows the procedure to be used regardless of skeletal maturity and reduces fracture complications, inadequate graft placement, and failure of fixation. Postoperative rehabilitation includes immediate knee motion from 0 degrees to 90 degrees and partial weight bearing.

Arthroscopy↗

Understanding and preventing noncontact anterior cruciate ligament injuries: a review of the Hunt Valley II meeting, January 2005.

The incidence of noncontact anterior cruciate ligament injuries in young to middle-aged athletes remains high. Despite early diagnosis and appropriate operative and nonoperative treatments, posttraumatic degenerative arthritis may develop. In a meeting in Atlanta, Georgia (January 2005), sponsored by the American Orthopaedic Society for Sports Medicine, a group of physicians, physical therapists, athletic trainers, biomechanists, epidemiologists, and other scientists interested in this area of research met to review current knowledge on risk factors associated with noncontact anterior cruciate ligament injuries, anterior cruciate ligament injury biomechanics, and existing anterior cruciate ligament prevention programs. This article reports on the presentations, discussions, and recommendations of this group.

Anterior Cruciate Ligament↗

Meniscal repair and transplantation: indications, techniques, rehabilitation, and clinical outcome.

The purpose of this paper is to provide current knowledge regarding the indications, operative techniques, rehabilitation programs, and clinical outcomes of meniscus repair and transplantation procedures. Meniscus tears that occur in the periphery may be repaired using a variety of operative procedures with high success rates. Complex multiplanar tears that extend into the central one-third avascular zone can also be successfully repaired using a meticulous vertically divergent suture technique. The outcome of these repairs justifies preservation of meniscal tissue, especially in younger athletic individuals. Meniscal transplantation is a valid treatment option for patients who have undergone meniscectomy and have related tibiofemoral joint pain, or in whom articular cartilage deterioration in the meniscectomized compartment is present. Rehabilitation after these operations includes knee motion and quadriceps-strengthening exercises initiated the first day postoperatively. The initial goal is to prevent excessive weight bearing and joint compressive forces that could disrupt the healing meniscus repair or transplant. The protocol contains modifications according to the type of meniscal tear, if a concomitant procedure is done (such as a ligament reconstruction) or if noteworthy articular cartilage deterioration is present. Patients who have repairs of peripheral meniscus tears are generally progressed more rapidly than those who have repairs of tears extending in the central one-third region or those who undergo meniscal transplantation. The safety and effectiveness of the rehabilitation program has been demonstrated in several clinical studies. We recommend preservation of meniscal tissue, regardless of age, in active patients whenever possible.

Humans↗

Two-strand posterior cruciate ligament reconstruction with a quadriceps tendon-patellar bone autograft: technical considerations and clinical results.

In patients with complete posterior cruciate ligament (PCL) ruptures in which 10 mm or more of increased posterior tibial translation is detected, associated knee disorders must be treated at the same time as the PCL injury. Varus malalignment and any abnormal medial or lateral ligament deficiency must be corrected before or with PCL reconstruction to avoid the risk of failure of the PCL graft. Gait retraining is recommended for patients with abnormal knee hyperextension patterns before ligament reconstruction is performed. Advances in PCL reconstruction include the use of a two-strand graft that may be placed using either a tibial inlay or an all-arthroscopic tibial tunnel technique. Biomechanical studies have shown a reduction in graft tension and improved load sharing in these constructs compared with single-strand reconstructions. The tibial inlay method can be used in athletic patients, and it also is required in PCL revisions in which a prior tibial tunnel must be avoided to achieve graft fixation. The tibial tunnel technique is used to treat dislocated knees for which reconstruction of multiple knee ligaments is required or when prior arterial injury or posterior skin or muscle damage limits the indications for a posterior open approach. Postoperative rehabilitation should protect the PCL graft from high forces and repetitive cyclic knee motions during the first 4 weeks postoperatively.

Humans↗

Anterior cruciate ligament revision reconstruction: results using a quadriceps tendon-patellar bone autograft.

BACKGROUND: The quadriceps tendon is a viable graft source for revision anterior cruciate ligament reconstruction. PURPOSE: To determine the functional results and graft failure rates in knees in which the patellar tendon had been previously harvested or was unavailable, expanded tunnels precluded the use of a semitendinosus-gracilis graft, or patients requested autogenous tissues instead of allografts for revision reconstruction. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: The authors observed 21 patients for a mean of 49 months postoperatively after revision anterior cruciate ligament reconstruction with a quadriceps tendon graft. The results were determined by KT-2000 arthrometer testing, the Cincinnati Knee Rating System, and the International Knee Documentation Committee Rating System. Fifteen knees required a concurrent procedure, including reconstruction of posterolateral structures in 5 knees, meniscal repairs in 5 knees, and high tibial osteotomy in 2 knees. RESULTS: Significant improvements occurred in symptoms (P < .0001), daily activities (P < .05), sports activities (P < .01), and the overall rating scores (P < .0001). Eighteen patients rated their knee condition as improved. Total mean anterior-posterior displacements decreased from 8.4 +/- 3.1 mm preoperatively to 2.0 +/- 2.3 mm at follow-up (P < .001). On the International Knee Documentation Committee knee ligament rating, 17 knees were graded as normal or nearly normal, 3 were graded as abnormal, and 1 was graded as severely abnormal. CONCLUSION: The revision operation provided reasonable results in this group of complex knees. However, the functional and overall results were inferior to those reported for primary anterior cruciate ligament reconstruction. Many knees (90%) had compounding problems of articular cartilage damage, meniscectomy, varus malalignment, or additional ligamentous injury that most likely affected the results.

Adolescent↗

Jump-land characteristics and muscle strength development in young athletes: a gender comparison of 1140 athletes 9 to 17 years of age.

BACKGROUND: Many authors have speculated that altered neuromuscular control and strength of the lower extremity are responsible for the gender disparity in knee ligament injury rates. HYPOTHESIS: Significant increases in normalized quadriceps and hamstrings strength and limb symmetry on single-legged hop test occur with age. No gender differences in strength occur until age 14 years, after which boys generate greater peak torques than do girls. Age and gender do not influence lower limb alignment on a drop-jump test. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: We studied the effects of age and gender in 1140 athletes, 9 to 17 years old, on muscle strength and neuromuscular control during functional activities. Isokinetic quadriceps and hamstrings strength was measured at 300 deg/s. Limb symmetry was assessed with single-legged hop tests. A video drop-jump test determined lower limb alignment in the coronal plane. RESULTS: Extension peak torques significantly increased with age; maximum strength was noted in girls at age 13 years and in boys at age 14 years (P < .001). Although maximum flexion strength occurred in boys at age 14 years (P < .001), girls had only slight increases from ages 9 to 11 years (P = not significant). Boys aged 14 to 17 years had significantly greater normalized isokinetic strength than did age-matched girls. No age or gender effects existed in limb alignment on the drop-jump test or limb symmetry on single-legged hop testing. CONCLUSION: Maximum hamstrings strength was noted in female athletes by age 11 years, compared with age 14 years in male athletes, and a distinct lower limb valgus alignment existed in the majority of all athletes on landing. The absence of a gender difference in lower limb alignment on landing suggests other factors may be responsible for the gender disparity in knee ligament injury rates.

Adolescent↗

Human meniscus allografts' in vivo size and motion characteristics: magnetic resonance imaging assessment under weightbearing conditions.

BACKGROUND: Although many reports have described clinical outcome of meniscus transplants, their size and motion patterns are not well understood. This study assessed postoperative in vivo size and motion patterns of meniscus transplants under full weightbearing conditions. HYPOTHESIS: The human meniscus transplant has size and motion characteristics similar to the native menisci. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Eight meniscus transplants in 7 knees were studied 15 to 34 months postoperatively. The knees were scanned in an open magnetic resonance imaging 0.5-T superconducting magnet while standing. Single slice sagittal and coronal images were obtained at 0 degrees , 30 degrees , 60 degrees , and 90 degrees of flexion in the operative and contralateral knees. RESULTS: The mean height and width of the anterior and posterior horns of the transplants were similar to those of native menisci. The millimeters of coronal displacement of motion of the midbody were also similar between the transplants and the native menisci. The anterior horn of the native medial menisci moved a mean of 5 mm more (total anterior to posterior translation, P < .05) than did the transplants. The posterior horn of the native medial menisci, and both horns of the native lateral menisci, also tended to move more than the corresponding horns of the transplanted menisci, although this result could not be confirmed statistically, given the number of menisci studied. CONCLUSION: Meniscus transplants had similar size and midbody motion characteristics as the native menisci. The horns of the meniscus transplants tended to show decreased motion compared with the native menisci. The operative techniques and subsequent healing of the graft bone and peripheral attachments provided a stable meniscus construct.

Adolescent↗

Assessment of lower limb neuromuscular control in prepubescent athletes.

BACKGROUND: Although neuromuscular indices have been extensively studied in adolescents and adults, limited data exist for prepubescent children. HYPOTHESIS: No differences exist between prepubescent boys and girls in lower limb strength, symmetry on single-legged hop testing, and limb alignment during drop-jump testing. STUDY DESIGN: Cross-sectional study (prevalence); Level of evidence, 1. METHODS: The authors tested 27 female and 25 male athletes who were aged 9 to 10 years and matched for both body mass index and years of organized sports participation. In a drop-jump screening test, the distance between the right and left hips, knees, and ankles was measured as an indicator of lower limb axial alignment in the coronal plane. The distance between the knees and ankles was normalized by the hip separation distance. Quadriceps and hamstrings strengths were measured isokinetically at 180 deg/s. Lower limb symmetry was determined from 2 single-legged hop function tests. RESULTS: Boys demonstrated greater mean absolute and normalized knee and ankle separation distances on the drop-jump test. Even so, 76% of boys had a normalized knee separation distance of 60% or less of the hip separation distance, as did 93% of girls, indicating a distinctly valgus alignment. There were no differences between the sexes in quadriceps and hamstrings peak torques, hamstrings/quadriceps ratio, time to peak torque, total work, or lower limb symmetry values. CONCLUSIONS: A high percentage of the prepubescent athletes studied had a distinctly valgus lower limb alignment during the drop-jump test and a lack of lower limb symmetry during the hop tests. These same indices have been hypothesized to increase the risk for knee ligament injuries in older athletes. Neuromuscular training may be needed to address these issues in children.

Biomechanical Phenomena↗

One- and two-strand posterior cruciate ligament reconstructions: cyclic fatigue testing.

This study examined how one- and two-strand posterior cruciate ligament (PCL) reconstructions resist the return of posterior translation during repetitive knee cycling. The femoral attachment of the one-strand graft and the anterior strand of the two-strand (AD2) grafts were located within the anterior one-third of the femoral PCL footprint. The second strand was placed within the middle third of the femoral footprint in one of three locations: middle-distal (MD), middle-middle (MM), or middle-proximal (MP). During repetitive knee cycling from 5 degrees to 120 degrees flexion with a 100 N posterior force, the intact knee had less than 1mm of residual posterior translation after 2048 flexion-extension cycles. Under similar cyclic conditions, the AD2-MM reconstruction achieved the most cycles before failure; however, this two-strand configuration failed in less than 700 cycles. The other reconstructions, either one strand or two strand, failed in less than 350 cycles. The surface failure location for 19 of 25 graft strands was within the femoral one-third of the strand. We concluded that one- and two-strand reconstructions under moderate loading and a range of motion from 5 degrees to 120 degrees flexion have an unacceptably high cyclic failure rate suggesting modifications of the allowable postoperative knee flexion and loading.

Aged↗

Posterior cruciate ligament revision reconstruction, part 2: results of revision using a 2-strand quadriceps tendon-patellar bone autograft.

BACKGROUND: Posterior cruciate ligament reconstructions fail for similar reasons as to why anterior cruciate ligament reconstructions fail. Revision surgery is an option after failure. PURPOSE: To prospectively study the results of 15 posterior cruciate ligament revision surgeries using a 2-strand quadriceps tendon-patellar bone autograft. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: The authors observed 15 knees that received the revision procedure a mean of 44 months (range, 23-84 months) postoperatively. The results were determined by a comprehensive knee examination including stress radiography and several grading scales. A tibial inlay technique was used in 9 knees, and an arthroscopic tibial tunnel technique was done in 6 knees. Six knees required 1 or more concomitant ligament reconstructions. RESULTS: Significant improvements occurred in pain, function, and patient perception scores (P < .05). However, only 53% returned to light sports without problems. Stress radiograph posterior tibial translation values improved from 11.7 +/- 3.0 mm pre-operatively to 5.1 +/- 2.4 mm at follow-up (P < .001). Two of the 15 revisions failed. Associated knee ligament reconstructive procedures restored anterior, medial, and posterolateral stability. There were no complications from the quadriceps tendon graft harvest site. Abnormal articular cartilage surfaces were found during the revision in 8 (53%) knees. CONCLUSIONS: The quadriceps tendon 2-strand revision provided reasonable results in this group of complex-injured knees. The tibial inlay approach is advantageous to bypass prior tibial tunnels, and the all-inside arthroscopic technique is advantageous when major concurrent ligament reconstructions are required.

Activities of Daily Living↗

Posterior cruciate ligament revision reconstruction, part 1: causes of surgical failure in 52 consecutive operations.

BACKGROUND: Posterior cruciate ligament reconstructions have not shown uniformly predictable results in restoration of normal posterior tibial translation. The authors are unaware of any study that has assessed the causes of failure of these operations, and they investigated 52 prior unsuccessful posterior cruciate ligament procedures to determine the factors that contributed to failure of the operations. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: The authors studied 52 prior failed posterior cruciate ligament surgeries that had been done in 41 knees (40 patients). Graft reconstructions had been done in 31 cases, primary repairs in 14, synthetic replacements in 4, and thermoplasties in 3. Medical records, operative notes, radiographs, and magnetic resonance imaging scans were reviewed, and a comprehensive knee examination was conducted. RESULTS: A single factor that caused the operations to fail was identified in 23 (44%) of 52 operations, and multiple factors were identified in 29 (56%). The most common probable causes of failure were associated posterolateral ligament deficiency (40%), improper graft tunnel placement (33%), associated varus malalignment (31%), and primary suture repair (25%). Sixteen of 21 (76%) prior posterolateral ligament procedures had failed, as had 9 of 19 (47%) prior anterior cruciate ligament reconstructions. Twenty-nine knees (71%) presented with pain with activities of daily living. Thirty-four knees (83%) had compounding problems of joint arthritis, prior meniscectomy, associated ligament deficiencies, or varus malalignment. Posterior cruciate revision surgery was done in 22 knees (54%). Eleven knees (27%) had severe joint damage that contraindicated revision, and 8 (19%) declined further operations. CONCLUSIONS: Failure to restore associated ligament instabilities and incorrect tunnel placement were major factors contributing to surgical failure. The results suggest the need for greater emphasis on the initial reconstruction in graft tunnel placement, correction of associated ligament instabilities, and correction of varus osseous malalignment. Failure of concurrent posterolateral ligament reconstructions was frequently encountered, suggesting the need for higher strength augmentation procedures or anatomical graft replacement.

Adolescent↗

Meniscal material properties are minimally affected by matrix stabilization using glutaraldehyde and glycation with ribose.

Knee meniscus replacement holds promise, but current allografts are susceptible to biodegradation. Matrix stabilization with glutaraldehyde, a crosslinking agent used clinically to fabricate cardiovascular bioprostheses, or with glycation, a process of crosslinking collagen with sugars such as ribose, is a potential means of rendering tissue resistant to such degradation. However, stabilization should not significantly alter meniscal material properties, which could disturb normal function in the knee. Our objective was to evaluate the effects of glutaraldehyde- and glycation-induced matrix stabilization on the material properties of porcine meniscus. Normal untreated meniscus specimens were tested in confined compression at one of three applied stresses (0.069, 0.208, 0.347 MPa), subjected to either a glutaraldehyde or glycation stabilization treatment, and then re-tested to measure changes in tissue aggregate modulus, permeability, and compressive strain at equilibrium. Changes in these properties significantly increased with glutaraldehyde concentration and exposure time to ribose. One glutaraldehyde and three glycation treatments did not alter aggregate modulus or compressive strain at equilibrium compared to controls (p > 0.10). However, all treatments increased permeability by at least 108% compared to controls (p < 0.001). This study reveals a dose-dependent relationship between meniscal material properties and certain stabilization conditions and identifies treatments that minimally affect these properties. Further research is necessary to determine whether these treatments prevent enzymatic degradation before and after surgical implantation in the knee.

Animals↗

The drop-jump screening test: difference in lower limb control by gender and effect of neuromuscular training in female athletes.

BACKGROUND: A valgus lower limb alignment has been noted during noncontact anterior cruciate ligament injuries. A video drop-jump test can indicate an athlete's ability to control lower limb axial alignment in the coronal plane. HYPOTHESES: Female athletes have decreased knee separation distances on landing and acceleration; male athletes have a neutrally aligned lower limb position. A neuromuscular training program will significantly increase knee separation distance in female athletes. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: The authors tested 325 female and 130 male athletes aged 11 to 19 years. The distance between the hips, knees, and ankles was measured during a drop-jump test. The separation distance between the knees and ankles was normalized by the hip separation distance. A neuromuscular training program (Sportsmetrics) was completed by 62 female athletes, and their jump-landing characteristics were reexamined. RESULTS: A marked decrease in knee separation distance was found on takeoff in 80% of female athletes and in 72% of male athletes. There was no difference between male and female athletes in the normalized knee and ankle separation distance during the landing and takeoff phases. The knee separation distance on landing was 23 +/- 9 cm in the female athletes and 22 +/- 8 cm in the male athletes. The normalized knee separation distance was 51% +/- 19% in the female athletes and 51% +/- 15% in the male athletes. After training, statistically significant increases were found in the female athletes in the knee separation distance on landing (29 +/- 8 cm, P < .0001) and in the normalized knee separation distance (68% +/- 18%, P < .0001). The trained female athletes had significantly greater knee separation distance and normalized knee separation distance than did the males (P < .0001). CONCLUSIONS: The majority of untrained female and male athletes demonstrated a valgus alignment appearance on the video test. After neuromuscular training, female athletes had improved knee separation distances and a more neutral lower limb alignment on landing and takeoff.

Adolescent↗