Heart transplantation as last resort against Brugada syndrome.
We report the first case, to the best of our knowledge, of a patient with Brugada syndrome who required heart transplantation to control multiple "electrical storms."
Biomedical subjects
Publications and source records attributed to Francis Wellens.
We report the first case, to the best of our knowledge, of a patient with Brugada syndrome who required heart transplantation to control multiple "electrical storms."
Recently, intraoperative radiofrequency ablation of the left atrium combined with mitral valve surgery has become widely used. In our center, 30 patients underwent this combined procedure; median sternotomy was used in 16 patients, and port access was used in 14 patients. At hospital discharge, 18 patients (60%) were no longer in atrial fibrillation, and at 6 months, 19 patients (65%) remained in sinus rhythm. All sinus rhythm patients had a well-defined transmitral A wave detectable by echocardiography. One patient sustained a major stroke. Two patients required pacemaker implantation. Such encouraging preliminary results have triggered worldwide interest in the percutaneous and surgical treatment of atrial fibrillation. However, the excellent long-term results with the classic Cox-Maze III operation have not yet been achieved with these newer approaches. Further basic and clinical research is required before a predictable simple and safe technique can be introduced as a new standard for the surgical treatment of atrial fibrillation in patients with or without structural heart disease.