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Biomedical subjects

Fabrizio Guarneri

Publications and source records attributed to Fabrizio Guarneri.

23 records · Page 2Linked to original sources
PubMedDate not supplied

The future: critical knowledge about anti-itch therapy.

Itch is an extremely frequent and enervating symptom of many diseases. Current anti-itch therapy, which is based almost exclusively on an "immunocentric" viewpoint, is often unsatisfactory. Recent studies show that this symptom is in fact the result of a complex interplay among skin, nervous system, endocrine system, and immune system. This explains the frequent failure of therapeutic strategies focused only on a single factor and suggests the usefulness of a polypharmacologic symptomatic treatment, designed on a case-by-case basis as a result of a multidisciplinary approach. We discuss the perspectives of anti-itch therapy in light of the new pathogenetic and pharmacologic acquisitions.

Antipruritics↗
PubMedDate not supplied

Some historical and epistemological remarks on itch and pruritus.

Although very common, itch is very hard to describe. It can be considered as one of the most distressing physical sensations we experience. Going back historically, old Latin and Greek writers cited it in ancient papers. So, etymology is of central importance to investigation in the field of itch, regarding the formation of a word with antique origins and different meanings. Scientists, poets, and painters for centuries tried to describe and represent itch. The study of their work reveals the development of the itch's significance. Today, a clinically relevant distinction defines pruritus and itch as two different sensations. Moreover, some terms like hyperknesis, alloknesis, atmoknesis, protopathic itch, and epicritic itch are described to approaching the complexity of this sensation and are utilized in clinical practice.

History, Ancient↗
PubMedDate not supplied

Strongyloidiasis histologically mimicking eosinophilic folliculitis.

The authors report an unusual case of strongyloidiasis in an Italian patient, who has always lived in Sicily. The patient presented with marked blood eosinophilia and an itching maculo-papular eruption, histologically simulating eosinophilic folliculitis. The clinical resolution was achieved after albendazol therapy.

Aged↗
PubMedDate not supplied

Trombiculiasis: clinical contribution.

Neotrombicula autumnalis is an arthropod usually living in the soil, except for the short period of the larval stage when it becomes a real parasite of warm-blooded hosts. We present a case of human trombiculiasis, which is unusual because of the parasite transmission from animals to humans, as in a typical synanthropic dermatosis.

Adult↗