[Omeprazole and misoprostol in acute gastroduodenal pathology. Physiopathological and therapeutic considerations in a surgical study].
In a clinical study on acute gastroduodenal pathology, the authors checked the therapeutical efficacy of Omeprazole and Misoprostol in comparison with H2-Antagonists. The study shows how Omeprazole could reduce to a half the treatment period necessary for H2-Antagonists to determine duodenal ulcer healing. Compared with these drugs, Omeprazole represents a real therapeutical progress. However, Omeprazole did not change the actual indications for surgical treatment in gastroduodenal ulcer. In drug-induced erosive gastritis treatment, Misoprostol proved to be unable to replace H2-Antagonists advantageously.