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Biomedical subjects

F Zechini

Publications and source records attributed to F Zechini.

At least 19 recordsLinked to original sources

[Omeprazole and misoprostol in acute gastroduodenal pathology. Physiopathological and therapeutic considerations in a surgical study].

In a clinical study on acute gastroduodenal pathology, the authors checked the therapeutical efficacy of Omeprazole and Misoprostol in comparison with H2-Antagonists. The study shows how Omeprazole could reduce to a half the treatment period necessary for H2-Antagonists to determine duodenal ulcer healing. Compared with these drugs, Omeprazole represents a real therapeutical progress. However, Omeprazole did not change the actual indications for surgical treatment in gastroduodenal ulcer. In drug-induced erosive gastritis treatment, Misoprostol proved to be unable to replace H2-Antagonists advantageously.

Acute Disease

Management of liver trauma.

A ten-year experience with the management of liver trauma is reported. The diagnostic approach is examined, stressing the role of selective arteriography. The management of the 78 observed cases is described. The need for biliary drainage to prevent postoperative leakages, is supported. Overall mortality in this series was 16.6%.

Adolescent

[Neoplastic occlusions of the large intestine (clinical study)].

The authors do a clinico-epidemiologic reviewing of 24 cases of neoplastic obstruction of large intestine, they had the opportunity to observe. Such patients represent 12.9% of all cases of mechanic intestinal obstruction. The obstructive complication, which in 70% of the observations involved sigma and rectosigmoid junction, was the clinical beginning of 9,6% of colonic and rectal carcinomata. Such disease arose preferably in old patients and in those suffering from one or more concomitant diseases. Some reflections about the surgical treatment, which, in this casuistry, determined a mortality of 25%, lead the Authors to think the requirements of the treatment of high risk patients and the rigid observance of the rules of colonic surgery should be put before the requirements of oncological radicalness.

Adenocarcinoma