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Biomedical subjects

F Y Lin

Publications and source records attributed to F Y Lin.

At least 127 records · Page 7Linked to original sources

[Thymectomy in Chinese myasthenia gravis].

From 1972 to 1986, 80 Chinese myasthenia gravis patients with thymectomy were studied. There were 25 males, aged from 21 to 70 years old (mean age 44) and 55 females aged from 12 to 56 years old (mean age 34). According to Osserman's criteria 10 patients belonged to grade I, 28 to IIa, 31 to IIb, 4 to III, 2 to IV and 5 to V. The postoperative follow ups ranged from 1 month to 13 years. The thymic pathology showed: hyperplasia in 44 cases, atrophy in 17 cases and presence of thymoma in 19 cases. The postoperative improvement occurred in 50% in thymomatous patients, 81% in non-thymomatous patients. There was no relationship between the duration of illness before operation and the postoperative status. However the patients with age onset after 40 had higher incidence of thymoma, and a higher rate of death from myasthenia gravis despite short duration of illness before surgery. All of 18 patients in whom serum was examined, the antiacetylcholine receptor antibody was detectable. The mean titres of this antibody in 8 hyperplasia patients, 3 atrophy patients and 7 thymoma patients were all higher than the mean value of 67 myasthenia gravis patients who did not received any treatment except anticholinesterase. Seven cases had postthymectomy followups of the antibody titres, 3 cases showed decreased antibody titre after thymectomy. Ten ocular myasthenic patients received thymectomy, 3 had thymoma, 5 had hyperplasia and 2 had atrophic thymus. The improvement rate in this group was around 71%.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Molecular epidemiology of neonatal meningitis due to Citrobacter diversus: a study of isolates from hospitals in Maryland.

Six cases of neonatal meningitis due to Citrobacter diversus were diagnosed in three Baltimore (Maryland) hospitals between 1983 and 1985. Using plasmid profiles, biotypes, serotypes, and chromosomal restriction endonuclease digests as epidemiological markers, we studied 63 isolates of C. diversus (including four isolates from cerebrospinal fluid) from these and seven other hospitals in Maryland. Within two of the three hospitals with meningitis cases, the same strain of C. diversus was isolated from case infant(s), healthy neonates, and nursery personnel. In all three hospitals, C. diversus strains different from those implicated as a cause of meningitis were also isolated. Other than the meningitis-associated strains, 15 different strains of C. diversus were isolated from infants in the hospitals studied, with several distinct clusters of asymptomatic, colonized infants identified.

Citrobacter↗

Persistence of cholera in the United States: isolation of Vibrio cholerae O1 from a patient with diarrhea in Maryland.

A case of cholera was identified in Baltimore County, Md., in October 1984. The Vibrio cholerae O1 isolate from the patient was hemolytic, biotype El Tor, serotype Inaba, and was toxigenic by the Y-1 adrenal cell assay; on Southern blot analysis, the strain had a unique HindIII restriction site in the cholera toxin gene identical to that of other U.S. V. cholerae O1 isolates. Two days before he became ill, the patient had eaten meat from crabs harvested along the Texas coast.

Aged↗

Kawasaki syndrome. A case-control study during an outbreak in Maryland.

An outbreak of 30 cases of Kawasaki syndrome (KS) occurred in Maryland from January through May 1983. The mean age of patients was 27 months; 60% were male. Rug shampoo exposure within one month and within six months of illness was not significantly greater in the 30 epidemic and seven sporadic cases than in their neighborhood and pediatric controls. These findings suggest that rug shampoo exposure may not be an important risk factor in the outbreak of KS in Maryland.

Child↗

Purification of soluble hepatocellular carcinoma extracts.

When soluble hepatocellular carcinoma (HCC) extract prepared by 3 M KCl solution was passed through a column of Sephadex G-200, four fractions (designated as I, II, III, IV) could be obtained from the elution profile. By leukocyte migration inhibition assay, the active component of soluble HCC extract which represented tumor-associated antigen was shown to be contained in fractions I and II.

Adult↗