Biomedical subjects

F X Roux

Publications and source records attributed to F X Roux.

116 records · Page 7Linked to original sources

PubMed1982

[Intra-cranial abscesses and congenital heart disease in children (author's transl)].

The authors report on 13 cerebral abscesses developed in children with cyanogenic heart disease. The abscesses have been treated by one or several punctures and by a general antibiotherapy adjusted to the germ when it was isolated. C.T. Scan and epidural Intra-cranial pressure monitoring have defined the Therapeutic tactics. The mortality rate is 7.7%. 60% of the survivors lead a normal life; 40% are mentally retarded; however this mental retardation is not directly related to the abscess; it appears to be a consequence of the cyanogenic cardiopathy. The neurological sequelae are one epilepsy and two visual defects compatible with normal life. Successive C.T. Scans in the months following treatment have shown the progressive disappearance of the abscess membranes. The conclusions of this study are under antibiotherapy, it is better to tap abscesses than to remove them and that their prophylaxy is the suppression of the shunt responsible of the cyanosis.

Adolescent↗

PubMed1982

[Use of the scanner in diagnosis and therapeutic surveillance of brain abscess].

Comparison from 102 cases of brain infections has been done between 2 periods: before and after 1978. The use of CT scan in routine since 1978 has not changed the number of patients diagnosed in acute phase (less than 15 days); but diagnosis was done before 2 days in 37% after 1978 and in 27% before 1978. However frequency of consciousness disorders is equal in both groups: 55%. By a semi-statistical analysis on 40 cases, 10 CT scan datas have been tested according to their sensibility and specificity to the diagnosis of brain abscess; 4 datas have a satisfying sensibility and specificity and are more accurate than the others: regularity of the shape, regularity of the enhanced ring; enhancement after injection, surrounding edema. Survey of 40 cases by CT scan has permitted to determine the average delay of disappearance of mass effect (20 days), of disappearance of the abscess (44 days) and the cicatricial aspects according to the treatment: puncture or excision.

Brain Abscess↗

PubMed1982

[Cerebral abscesses in children treated by puncture. A 16 year-experience].

In the last 16 years, 33 children have been treated for brain abscesses. Fifteen (45.5%) presented with cyanogenic congenital heart disease; eleven (33.5%) with E.N.T. infection. The standardized treatment protocol included puncture of the abscess, antibiotherapy and anti-edematous drugs. Postoperative permanent epidural ICP monitoring and, in the last 6 years, repeated CT scans indicated when it was necessary to tap the abscess again or to reinforce the anti-edematous treatment. However, in 3 of these 33 cases, the abscess had to be removed. Postoperative mortality rate was 3%. Overall mortality rate was 6%. Neurological sequelae were slight. Epilepsy occurred in 10%. Mental retardation (16%) was only found in children with cyanogenic congenital heart diseases. Repeated CT scans showed the progressive disappearance, within a few months, of the abscess membranes. This study shows an improvement in the results when brain abscesses in children are punctured rather than excised.

Brain Abscess↗

PubMed1982

[Congenital intraspinal neuroblastomas. A propos of 7 cases treated surgically].

Neuroblastomas appear to be one of the most frequent congenital solid tumors. Nevertheless, intraspinal congenital neuroblastomas are uncommon. The authors report seven cases of congenital intraspinal neuroblastomas operated on in the "Service de Neurochirurgie des Enfants-Malades" from 1970 to 1980. Their study and that of 16 cases published in the literature allows to stress several points (7, 12). The dumb-bell intraspinal neuroblastomas present a large extension. They usually determine a severe and definitive paraplegia. They probably have a long prenatal evolution. The tumoral prognosis of these congenital neuroblastomas is good. Success should be expected in nearly 80% of the cases. Surgery, in two steps, intra and extra spinal, remains compulsory even though the neurological prognosis is poor. It is useless to operate upon the neuroblastomas as emergencies, when neurological involvement is total at birth. The complementary treatment, X ray-therapy or chemotherapy is not without any danger on newborns. It necessary is not proved.

Female↗

PubMed1980

[Herpes encephalitis treated using adenine-arabino-side and followed-up by densitometry (author's transl)].

In a 52-year-old man suffering from encephalitis, immunofluorescent study of cerebral tissue led to a diagnosis of herpes encephalitis 4 hours after biopsy. Cell cultures on the fourth day confirmed the diagnosis. Such a hypothesis had already been advanced before biopsy on the basis of the electroencephalogram which showed electrical changes with a periodic tendency. Following treatment with adenine-arabinoside, motor deficit and aphasia disappeared in one month whilst there was a parallel increase in antibody levels in the blood and cerebrospinal fluid.

Encephalitis↗

PubMed1980

[Meningioma of infants and children (author's transl)].

The authors report 11 meningiomas observed on infants and children. They point out four items: --In children the diagnosis of intraspinal meningiomas is impossible before surgery while diagnosis of intracranial meningiomas should be possible since in this case the neuroradiological investigations are most often characteristic. --The total removal of intraspinal meningiomas less than (en plaque) is not always possible. --In intracranial meningiomas detected on children less than five years-old, asymmetric macrocrania is very frequent. --Since infants' intracranial meningiomas are sometimes very large, it is likely that the tumor is congenital.

Adolescent↗

PubMed1980

[Cerebral infections due to anaerobic organisms (author's transl)].

Most of intracranial suppurations, especially those from E.N.T. origin, are secondary to anaerobic germs, which can be cocci Gram (+) or Gram (-), in association or not with aerobic bacteria. 97 cases have been observed between 1968 and 1979 at Lariboisière Hospital. When the bacteriological study was realised in correct conditions, anaerobic germs were found in more than 60% of cases, and less than 10 % of cultures were negative. A lower mortality (11 %) and morbidity (34 %) rates follow an improvement in bacteriological diagnosis. Anaerobic bacteria stay very susceptible to antibiotics, such as the association Penicilline-Metronidazole; now, we prescribe immediately such a therapeutic, and eventually modify it after having received the antibiogram. As a conclusion, the treatment of brain abscesses could be simplified: CT scan and a rigourous bacteriology make possible an accurate control and follow-up of the suppuration after simple punction.

Anti-Bacterial Agents↗

PubMedDate not supplied

Extradural spinal tophaceous gout: evolution with medical treatment.

A patient with chronic tophaceous gouty arthritis developed paraparesis due to medullar compression from a urate sodium tophus. We report the MRI features of this tophaceous gout, which showed an extradural hyperintense signal with an isointense nodule signal on T1 weighted sequences. Surgical removal of the epidural lesion resulted in complete clinical recovery. At the upper level of the spine, an extension of the epidural lesion was not removed, but after one year of medical treatment of the gout, MRI showed regression of the epidural compression.

Arthritis, Gouty↗