Biomedical subjects

F W Henriksen

Publications and source records attributed to F W Henriksen.

At least 37 records · Page 2Linked to original sources

PubMed1979

Angiography in the diagnosis of carcinoid syndrome.

The diagnosis of carcinoid syndrome has been confirmed by selective abdominal angiography in a consecutive series of 18 patients. In eight patients the primary carcinoid tumour was removed before angiography. The primary lesion was demonstrated in eight of ten cases. Metastases from the carcinoid tumours was present in all 18 patients. All cases of mesenteric metastases and 12 of 14 cases with liver metastases were visualized by angiography. All but one of the liver metastases were highly vascularized and therefore easy to recognize, making angiography a good monitor in the control of medical therapy or in planning of surgical intervention.

Abdominal Neoplasms↗

PubMed1979

Clinical diagnosis of metastatic carcinoid tumours.

Eighteen patients with metastatic carcinoid tumours were admitted to surgical gastroenterological department of Rigshospitalet during the period 1974--1978. Thirteen had primary carcinoid tumours in the terminal ileum, two in the lungs, one in the pancreas, one in the testis, and one possibly in the retroperitoneum. All patients had distant metastases, 13 in the liver. Carcinoid syndrome with flusing and diarrhoea was present in 15 patients (83%). The time elapsing from onset of symptoms until diagnosis was on an average 2 1/2 years. The most valuable screening test for carcinoid syndrome was determination of the excretion of 5-hydroxy-indol- acetic-acid. The most sensitive investigation for determination of primary tumour and/or metastases was abdominal angiography, which was positive in all cases. Other radiological investigations were less sensitive.

Adult↗

PubMed1979

Cimetidine treatment of recurrent ulcer.

Twenty-one consecutive patients with endoscopically proven recurrent ulcer were treated continuously with cimetidine, 1 g daily for 8 weeks. After 4 weeks' treatment 18 (86%) of the patients were free of symptoms, and the ulcers had healed in 17 (81%). At the 8th-week examination symptoms had disappeared, and ulcers were healed in 19 patients (91%). Within 6 weeks after withdrawal of cimetidine six patients (28%) presented recurrence of ulcers and symptoms. This study demonstrates that recurrent ulcer patients respond to cimetidine with regard to healing of ulcers and disappearance of symptoms, as do unoperated duodenal ulcer patients. Because operation for recurrent ulcer carries an increased mortality, we suggest that cimetidine should be attempted in the treatment.

Adult↗

PubMed1978

Long-term results after excisional surgery for Chrohn's disease of the terminal ileum.

Resection with the object of cure was undertaken in 20 patients with Crohn's disease in the terminal ileum. These patients were followed up more than five years after operation. Recurrence took place in eight patients, in half of them more than five years after the primary operation. Six patients were submitted to reoperation and two died. Seven out of the eight recurrences were localized to the anastomosis. These results may support the results of a bigger Swedish material which favours more radical primary resections in Crohn's disease.

Adolescent↗

PubMed1977

Gardner's syndrome. Report of three cases and review of the literature.

Three cases of Gardner's syndrome are reported. Two patients had one and two carcinomas in the colon respectively. Postoperatively the two patients developed desmoid tumours in the abdominal wall, and one of them also an intraabdominal desmoid. The literature is briefly reviewed with respect to diagnosis and treatment of the components of the syndrome. A special section is devoted to the differentialdiagnostic problems. The reports from the last years concerning this problem are surveyed, and the rationale for maintenance of Gardner's syndrome and familial polyposis of the colon as two different genetic entities is questioned.

Adult↗

PubMed1976

Inhibition of gastric secretion by exogenous secretin and cholecystokinin in normals and duodenal ulcer patients.

The inhibitory effect of combined secretin (0.5 and 1.0 clin. unit/kg b.w./hour) and cholecystokinin (0.5 and 1.0 IDU/kg b.w./hour on the pentagastrin-stimulated (0.15--1.0 and 6.0 ug/kg b.w./hour) gastric secretion was investigated in twelve volunteers and in twelve duodenal ulcer patients. Regardless of the dose level no difference was found between normals and duodenal ulcer patients, indicating that a decreased sensitivity to secretin and cholecystokinin is not a pathogenetic factor for the development of duodenal ulcer.

Adult↗

PubMed1976

Combined effect of glucagon and cholecystokinin on gastric secretion in man.

The inhibition of the pentagastrin-stimulated (1 ug/kg b.w./hour) gastric secretion by glucagon (20 ug/kg b.w./hour), cholecystokinin (0.5 IDU/kg b.w./hour), and a combination of these were investigated in 7 volunteers. Glucagon as well as CCK given isolated inhibited the gastric secretion, but no augmentation of inhibition was demonstrated when the hormones were in combination.

Adult↗

PubMed1976