Biomedical subjects

F Vollmar

Publications and source records attributed to F Vollmar.

At least 37 records · Page 2Linked to original sources

PubMed1976

[Coronary atherosclerosis, coronary thrombosis and myocardial infarction in autopsy cases (author's transl)].

The autopsy reports of the Pathological Institute Erfurt of the period from 1. 1. 1951 until 31. 12. 1969 were scored for cases of myocardial infarction which were analyed concerning frequency and distribution of age, and sex, resp. The informations were transferred to punched cards and processed with electronic data equipment. In 8.26 per cent of all autopsies (males 10.32 per cent, femals 5.78 per cent) a myocardial infarction was present. During the period of nineteen years a significant increase of the myocardial infarctions was observed. Callous infarcts were more frequent than fresh and relapsing. Most of the infarcts were found in the posterior wall of the left ventricle.

Adolescent↗

PubMed1976

[Coronary atherosclerosis, coronary thrombosis and myocardial infarction in autopsy cases. 1st communication: Preliminary investigations: atherosclerosis of the aorta and the large arteries (author's transl)].

28978 autopsy reports of young (after the 14th year of age) and adult patients autopsied during the period from 1.1 1951 until 31. 12 1969 were scored for atherosclerotic changes of the aorta and the large arteries. The informations were transferred to punched cards and processed with electronic data equipment. The methods of the statistical evaluation are described. 52.96 per cent of the cases revealed an aortic atherosclerosis. 17.96 per cent showed an atherosclerosis of the cerebral arteries, 31.16 per cent of the cases had atherosclerotic changes of the kidneys. All groups of diseases showed an increase during the observation period. No sex differences were detected.

Adolescent↗

PubMed1976

[Experimental model of coronary thrombosis in the closed thorax in swine].

Coronary thrombosis was induced in 14 miniature pigs by means of direct current. The induction electrode was introduced via the common carotid artery into the coronary artery. The intensity of current (1 mA) and the duration of current flow (60 min) were kept constant in all the experimental animals. 6 miniature pigs survived the period of observation (48 h). In all instances, an injury to the intima was the morphopathological location factor. With the exception of one animal, which died after an induction time of 60 min, coronary thrombosis was stated in all the miniature pigs. The experimental arrangement which produces closed-thorax coronary thrombosis is suited for cardiosurgical, physiopathological and pharmacological experiments, especially because the anatomy and the degree of development of the porcine heart are most similar to those of the human heart.

Angiography↗

PubMed1976

[Experimental coronary thrombosis in dogs. Morphologic investigations (author's transl)].

By means of electric induction without opening the chest in 23 dogs coronary thromboses were produced with the aid of a standardized method based on a test model of Salazar (1961). The morphological results are reported. 13 of the dogs showed coronary thromboses. At the same time in 12 animals a myocardial infarction could be registered. Altogether, we observed 17 myocardial infarctions. The electric field led to differently severe lesions in the walls of the coronary arteries. The significance of this test model is discussed.

Animals↗

PubMed1976

[Morphologic investigations on experimental coronary thromboses in pigs (author's transl)].

With the aid of a standardized method basing on a report of Salazar (1961) coronary thromboses in pigs were produced by means of electric induction without opening the chest. 12 of 13 pigs showed thromboses in coronary arteries, in 8 animals with embolization of the thrombotic material. At the sametime in 8 pigs a myocardial infarction could be registered. The significance of these experiments discussed.

Animals↗

PubMed1976

[Coronary atherosclerosis, coronary thrombosis and myocardial infarction in autopsy cases (author's transl)].

The autopsy reports of the Pathological Institute Erfurt of the period from 1.1 1951 until 31.12. 1969 were scored for cases of coronary sclerosis which were analysed concerning frequency and distribution of age and sex, resp. In 52.26 percent of all autopsies (55.77 percent of men, 48.06 percent of women) a coronary sclerosis was present. Weak or moderately severe coronary sclerosis appeared more frequent (34.47 percent) than severe forms (17.80 percent of all autopsies). The difference in the relative frequency of coronary sclerosis between our material and the data of other authors we explain by subjective factors in the interpretation of the morphological changes of the coronary vessels. Males suffered significantly more frequent from all forms of coronary sclerosis. During the period of nineteen years a significant increase of the coronary sclerosis was observed. It is due to the more frequent occurrence of weak to moderately severe coronary sclerosis in both sexes, and of severe forms in men. The increase of the frequency of the coronary sclerosis particularly concerns the younger age groups.

Adolescent↗

PubMed1975

[An experimental model of electrically-induced coronary thrombosis in the closed chest].

The authors report on an experimental model of coronary thrombosis, electrically induced in the closed thorax. By this technique they succeeded inducing coronary thrombosis with myocardial infarction in 13 cases out of 21. In three cases just disseminated myocardial necrosis was proved. All of the other animals showed vast myocardial infarctions. Coronarography, arterial pressures, typical shifts of serum enzymes, decrease of thrombocytes and fibrinogen and elevation of spontaneous fibrinolysis during the first hours proved to be valuable for the confirmation of successful inducing of thrombosis; in individual cases, however, these estimations yield no absolute certainty.

Animals↗

PubMed1975

[The correlation of clinical-electrocardiographic criteria with pathologic-anatomical findings in myocardial infarct].

Electrocardiographic signs of myocardial infarction obtained in 591 patients by the corrected orthogonal lead system according to Frank were compared with corresponding results of autopsy-proven material and corrected. By the corrected orthogonal lead system myocardial infarction could be recognized in 89% of the autopsy-proven cases. Moreover, electrocardiographic alterations which suggest accompanying mono- or biventricular hypertrophy were demonstrated.

Adult↗

PubMed1974