[Malignant melanoma in Spain. Cooperative clinicopathologic study of 513 cases].
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Biomedical subjects
F Vanaclocha
Publications and source records attributed to F Vanaclocha.
An unusual form of Mycobacterium chelonei infection. The problem of differential diagnosis of cutaneous infections with granules.
We report a patient with a cutaneous infection produced by Mycobacterium chelonei and histologically manifested as granules like those usually seen in a heterogeneous group of infections. We review the differential diagnosis of this morphological form of micro-organisms in tissues.
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Oral involvement in mycosis fungoides: report of two cases and a literature review.
Oral involvement is uncommon in cutaneous T-cell lymphomas and usually associated with poor prognosis. The clinicopathological and immunohistochemical findings of 2 new cases are described along with a literature review. The first patient had a 10-year history of mycosis fungoides when she developed lesions in the oral tissues. She died 6 months later despite treatment. The immunophenotype was CD3+, CD4+, CD8-, CD30-. The second patient had a mycosis fungoides for 5 years when she developed lesions in the uvula and oropharynx. She was treated with polychemotherapy and she is alive 5 years after oral involvement. The immunophenotype was CD3+, CD4-, CD8+, CD30-. There are conflicting reports about the prognosis in the CD8+ phenotype. The present cases and the literature review seem to indicate that in oral involvement the CD8- phenotype is not associated with a worse prognosis than the CD4+ subtype. However, it is necessary to study new cases to confirm this statement.
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