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Biomedical subjects

F Valtot

Publications and source records attributed to F Valtot.

At least 37 records · Page 2Linked to original sources
PubMed1992

[Ultrasonic treatment of hypertonia caused by intraocular silicone oil].

The authors treated 53 patients with uncontrolled glaucoma in silicone oil filled eyes with high intensity focused ultrasound. The silicone oil filled eyes present unusually difficult problems in glaucoma management, since the silicone oil rapidly obstructs filtration openings, and laser techniques have not been effective. The mean pretreatment pressure was 34.2 mmHg. The patients were followed for a mean of 17 months. Seventy-five per cent of ultrasound treated eyes had successful reduction of intraocular pressure to below 20 mmHg with or without concomitant medical treatment at two years after treatment. The complication rate was low in this group of eyes. Five eyes developed hypotonia and three eyes had full thickness scleral perforations but were effectively controlled and developed no other complications during two years of follow-up. This technique appears more effective than cyclo-destructive techniques alone.

Adolescent↗
PubMed1992

Therapeutic ultrasound for the treatment of glaucoma.

We present a summary of the results obtained on 1142 treatments of 1072 eyes treated in our hospital during the last 5 years. Ultrasound has been used to treat 843 eyes with refractory glaucoma and also to restore failed trabeculectomy filtering blebs in 229 eyes. The single treatment success rate with success defined as an IOP > or = 20 mm Hg was 59% at one year and 46% at 3 years. In cases of failed blebs, ultrasound treatment performed 3 to 12 weeks after trabeculectomy revived the blebs of 82% of the phakic eyes when 5 FU subconjunctival injections were performed in the following days.

Glaucoma↗
PubMed1989

Treatment of glaucoma with high intensity focused ultrasound.

Focused high intensity therapeutic ultrasound has been used since 1982 by Coleman and all, to treat patients with uncontrollable intraocular pressure. Three mechanisms may be responsible for lowering intraocular pressure: decreased aqueous humor production in the ciliary epithelium, transscleral outflow of aqueous humor, and increased uveal outflow. We began the use of focused ultrasound to treat glaucoma in April 1987. Up to now (April 1988), we have treated 220 patients. We describe results from patients that had a follow up of 3, 6, 12 months. Successful treatment resulting in pressure less than 20 mm Hg, was obtained in over 80% of patients treated at 90 days post treatment and of 50% after 6 and 12 months. The complication rate is low. Retreatment is safe and effective. Additionally, the use of U.S. to open closed filtering blebs, recently postoperative, has been a success in 90% of the treated eyes after 3 months. The follow-up period of this study is short which makes conclusions about long-term effects and side effects not possible.

Follow-Up Studies↗
PubMed1985

[Results 1 year after trabeculoretraction by 360 degree argon laser in the treatment of open-angle glaucoma].

On 210 glaucomatous patients (119 men, 91 women), 390 eyes with open angle chronic glaucoma, we have performed an argon laser trabeculoplasty according to Wise technique (360 degrees in one time). ALT was presented as an alternative to surgery. Therefore results were appreciated so that ALT allowed or not to avoid surgery. After one year, the rate of failures was: on all the 390 eyes: 15 p. cent on O.A.C.G. simplex: 6.7 p. cent on myopic glaucoma: 7 p. cent on pigmentary glaucoma: 29.5 p. cent on capsular glaucoma: 6 p. cent after trabeculectomy: 62 p. cent on aphakic glaucoma: 50 p. cent on secondary glaucoma: 33 p. cent on combined glaucoma: 0 p. cent In the group of successful results, ALT allowed to lower medical treatment in at less 70 p. cent after one year of follow-up except for pigmentary glaucoma where, in almost all cases, medication before ALT had to be continued.

Age Factors↗
PubMed1982

[Technique employing argon laser coagulation to obtain trabecular retraction].

A technique for treating primary open angle glaucoma by argon laser photocoagulation is described. Its elective action on the trabeculum and on trabecular "collapse" in the absence of any trabecular perforation suggested the name of "trabecular retraction" for this procedure. Its efficacy depends on very good visibility of the trabeculum through 360 degrees, on perfect focalization of the point of impact to 50 mu, and on the application of one hundred or so impacts distributed throughout 360 degrees. Any pretrabecular obstacle must be eliminated. Mean pressure drap obtained is 10 mmHg. Complications are minimal and results comparable or superior to those of surgery.

Aged↗
PubMedDate not supplied

Nonpenetrating deep sclerectomy: a 6-year retrospective study.

PURPOSE: Nonpenetrating trabeculectomy, also called nonpenetrating deep sclerectomy (NPDS), is a filtering surgery where the internal wall of Schlemm's canal is excised, allowing subconjunctival filtration without actually entering the anterior chamber. This, technique was developed to minimize the complications of trabeculectomy. The authors investigated its safety and efficacy in a retrospective noncomparative study. METHODS: A total of 258 eyes (179 patients, mean age 61.4 +/- 11.56 years) with uncontrolled open angle glaucoma with prior medical therapy were treated. NPDS with a biocompatible collagen device (157 eyes) sutured to deep scleral bed or with the use of a 5-fluorouracil sponge (90 eyes) were analyzed. The main outcome measure was postoperative intraocular pressure (IOP) with an average follow-up of 54.4 +/- 17.07 months (range 1-85). Efficacy was determined 1 month, 3 months, and every 6 months after the procedure for 6 years. RESULTS: Mean preoperative IOP was 24.47 +/- 5.92 mmHg. Mean postoperative IOP was 14.44 +/- 5.31 mmHg (average lowering of the IOP was 38.94 +/- 23.81%) at 1 month, 15.16 +/- 4.57 mmHg (35.73 +/- 21.35%) at 3 months, 15.87 +/- 4.24 mmHg (32.45 +/- 20.52%) at 6 months, 16.32 +/- 4.53 mmHg (29.96 +/- 23.69%) at 12 months, 17.12 +/- 4.45 mmHg (26.51 +/- 23.93%) at 18 months, 16.77 +/- 4.44 mmHg (28.18 +/- 21.73%) at 24 months, 16.43 +/- 4.15 mmHg (28.89 +/- 23.69%) at 30 months, 16.34 +/- 4.12 mmHg (30.05 +/- 21.61%) at 36 months, 16.16 +/- 4.01 mmHg (30.06 +/- 22.55%) at 42 months, 15.71 +/- 3.74 mmHg (32.49 +/- 19.08%) at 48 months, 15.61 +/- 3.48 mmHg (31.26 +/- 21.01%) after 5 years, and 15.81 +/- 3.79 mmHg (33.73 +/- 20.9%) after 6 years. YAG goniopuncture was performed in 47.3% of cases with a mean follow-up of 12 +/- 13 months. These goniopunctures were effective in lowering IOP after a long-term follow-up (24 months). Additional 5-fluorouracil injections were used in 7% of cases. Visual field (Octopus or Humphrey mean defect and corrected loss variance or loss variance) was not modified (p < 0.01). Number of preoperative glaucoma medications was 2.01 +/- 0.58 and number of postoperative glaucoma medications was 0.85 +/- 0.92. Complications were peroperative microperforations in 27 eyes (10.5%), shallow anterior chamber in 2 eyes, hyphema in 2 eyes (0.8%), cataract in 5 eyes (2%), and dellen in 1 eye (0.4%). No cases of endophthalmitis or choroidal detachment were found. After surgery, 23 eyes (8.9%) required a new filtering surgical procedure, and diode laser cyclophotocoagulation was necessary in 2 eyes (0.8%). The probability success rate, defined as an IOP lower than 21 mmHg, was 66.46% (Kaplan Meier) at 60 months off all glaucoma medications and 80.32% with medical or new surgical treatment. CONCLUSIONS: NPDS appears to be an effective and safe filtering procedure for lowering IOP and could be an alternative to trabeculectomy in open angle glaucoma with the advantage of having fewer complications.

Adult↗
PubMedDate not supplied

[Principles and histologic effects of the treatment of hypertension with focused high-intensity ultrasound].

Focused high-intensity ultra-sound is used to treat glaucoma. Histopathologic examinations of rabbit and pig eyes following therapeutic ultrasound demonstrated highly localized lesions including destruction of the ciliary epithelium and thinning of the sclera. The bond between the sclera and the ciliary epithelium is weakened. The conjunctiva remains intact. The histologic findings in human eye enucleated after ultra-sound therapy are identical. Three mechanisms for pressure reduction are proposed: transscleral outflow of aqueous humor can occur under the overlying conjunctiva; focal destruction of the ciliary epithelium can reduce aqueous production; scleral scarring produces the potential for separation of the ciliary body and the sclera.

Animals↗
PubMedDate not supplied

[The treatment of failed trabecular surgery in glaucoma with ultrasound (Sonocare)].

We have treated 62 recently post-operative eyes with non functioning trabeculectomies at the site of the failed bleb with one to four ultrasound applications each of five seconds duration and at an intensity level of 10 kw/cm2; 32 eyes were phakic, 7 aphakic, and 23 pseudophakic (anterior or posterior chamber). The two groups of patients showed the best response when the ultrasound treatment was performed three to twelve weeks after the last trabeculectomy; 82% are success in the phakic group, and 68% in the aphakic or pseudophakic group after three months. After the ultrasound treatment, 5FU subconjunctival injections seem to be effective in the very bad cases with a low rate of complications.

Aged↗