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Biomedical subjects

F Vakilzadeh

Publications and source records attributed to F Vakilzadeh.

17 recordsLinked to original sources

[A lupus-vulgaris like atypical mycobacteriosis caused by Mycobacterium xenopi (lupus xenopi)].

A case of lupus-vulgaris-like infection caused by Mycobacterium xenopi in a 62-year-old immunocompetent female patient is presented. A large cutaneous infiltration was seen in the right periorbital region. Histological examination revealed a granulomatous reaction of epithelioid cells and giant cells. M. xenopi was isolated from biopsy material and tuberculosis could be excluded. Isoniazid was effective in healing the lesion within a year. Such infections are well known for other mycobacteria but to our knowledge had not yet been described for M. xenopi. The characteristics of human infections with M. xenopi are summarized in a review of the literature and criteria for the diagnosis of atypical cutaneous mycobacterioses are proposed.

Biopsy

Autosomal dominant ichthyosis exfoliativa.

An unusual ichthyosiform dermatosis with circumscribed areas of blistering hyperkeratoses as well as scaly areas was observed in five consecutive generations of a German family. Light and electron microscopical studies revealed oedema of the keratinocytes in the upper epidermis but no defects of tonofilaments and keratohyalin granules. We suggest that this type of ichthyosis exfoliativa inherited as an autosomal dominant trait represents a new and distinct entity.

Adult

[Bilateral segmental neurofibromatosis].

Segmental neurofibromatosis is a rare type of neurofibromatosis. We report a case of bilateral manifestation, review the literature on this extremely uncommon variant, and discuss the possible causative mechanisms and the genetic risk of segmental neurofibromatosis.

Adolescent

[Erythrokeratodermia anularis migrans--a new genetic dermatosis?].

An unusual type of erythrokeratodermia in an 11-year-old boy is presented. It can be distinguished from the well-known classic types of erythrokeratodermia by clinical criteria, such as the persisting, very slowly migrating, annular lesions, and also by immunohistochemical and ultrastructural findings. In view of the distinct clinical features of this new genodermatosis, the term erythrokeratodermia annularis migrans is proposed.

Biopsy

[Pomade crust].

Exaggerated use of skin care topicals in infants may lead to brownish appositions in the inguinal and gluteal region described as pomade crust. Examination of scraping material by infra-red spectroscopy failed to reveal any residue of emollients but instead was characteristic of human scales. Certain topicals are apparently capable of inducing hyperkeratosis in these body regions.

Age Factors

[Acne vulgaris].

Explore the source record for details and available documents.

Acne Vulgaris

[Clinical findings in porphyria cutanea tarda].

Disturbances in the iron metabolism can quite frequently be observed in patients with porphyria cutanea tarda. Studies on 10 patients with porphyria cutanea tarda indicate that elevated iron levels are correlated with decreased latent and normal total iron binding capacity in the serum. Morphological examinations of the liver showed alterations as can be found in fatty liver up to cirrhosis, which -- in most instances -- were associated with iron deposits in the hepatocytes.

Adult

[Linear pigmentation of nails].

A case of linear pigmentation of three fingernails is reported. Following extraction of the nail of the thumb the matrix displayed a 2X4 mm circumscribed pigmented area. Histologic examination revealed a junction nevus.

Adult

[Ascher's syndrome].

A case of Ascher's syndrome with blepharochalasis and double upper lip is described. It is emphasized that the combined appearance of these two symptoms is essential for the definition of this syndrome.

Blepharoptosis

[Focal dermal hypoplasia with apocrine nevi and striation of bones (author's transl)].

In a 22 year-old female patient affected with focal dermal hypoplasia, multiple apocrine nevi occurred in the sternal region; these nevi may be part of the syndrome. Roentgenograms of the long bones revealed marked longitudinal striations. This anomaly represents a characteristic and hitherto underestimated feature of the syndrome.

Abnormalities, Multiple

Keratosis palmo-plantaris cum degeneratione granulosa.

Two cases of keratosis palmo-plantaris cum degeneratione granulosa Voerner are reported. A brief description of the characteristics of the clinical and histologic aspects of the disease is given and the mode of inheritance within the family affected is discussed.

Diagnosis, Differential

[Hydrotherapy in cauterization wounds. A histologic study (author's transl)].

Investigations have have been carried out in guinea pigs to test the usefullness of hydrotherapy. Concentrated sulfuric acid was applied to the skin for a period of 30 sec and 5 min. After this the skin was washed with tap water for 1 hr. The treated area was then subjected to macroscopic and microscopic examination. When the acid was applied for 30 sec, followed by rinsing, an almost complete restitution of the skin was found on the test area macroscopically and microscopically. Significant differences were also observed after an exposition of 5 min in comparison with untreated control animals.

Animals