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Biomedical subjects

F Truchetet

Publications and source records attributed to F Truchetet.

At least 37 records · Page 2Linked to original sources
PubMed1997

[Arterial leg ulcers].

Explore the source record for details and available documents.

Anti-Infective Agents, Local↗
PubMed1997

[Diffuse pigmentation (nail, mouth and skin) associated with HIV infection].

INTRODUCTION: Nail dyschromia in patients infected with human immunodeficiency virus (HIV) was first described in 1987 by Furth and Kazakis. It has since been reported in patients with the acquired immunodeficiency syndrome (AIDS), predominantly in patients treated with zidovudine. CASE REPORT: We describe the case of a 37 years old white woman, who developed AIDS in 1994, with nail longitudinal colored bands, oral and cutaneous pigmentation without taking zidovudine. DISCUSSION: There have been four reports of nail pigmentation in HIV-infected patients who had no received this antiviral agent. The singularity of our case is the onset in a white woman. A lot of causes must be evoked and biology must be done, with histopathologic study when it is possible.

Adult↗
PubMed1996

Recurrent annular erythema with purpura: a new variant of leucocytoclastic vasculitis responsive to dapsone.

Annular lesions are rarely reported in the clinical spectrum of leucocytoclastic vasculitis, except in the acute haemorrhagic oedema of the skin. We report three patients who suffered from an extraordinary recurrent annular dermatitis, for 4 years in one case and for decades in the other two. The eruption was characterized by purpuric lesions that had a centrifugal evolution, creating target- or polycyclic patches disseminated on the limbs and trunk. The patients' general condition remained excellent during the attacks. All lesions spontaneously disappeared within 2 weeks, but recurred monthly. In all three cases, the histological changes were consistent with leucocytoclastic vasculitis. One patient had ulcerative colitis and another had a benign immunoglobulin A (IgA) monoclonal gammopathy. These two patients showed a good response to dapsone therapy. This dermatosis probably represents a new and rare variant of leucocytoclastic vasculitis.

Dapsone↗
PubMed1996

[Digestive involvement in dystrophic bullous epidermolysis. Presentation of 2 cases and review of the literature].

Congenital epidermolysis bullosa is an inherited disorder characterized by an anomaly of joint structures between epidermis and dermis. This anomaly involves different malpighian epithelium and particularly in the digestive chorioepithelial junction. Digestive and oropharyngeal manifestations include bullae, erosions and ulcerations that heal by fibrosis, leading to retraction and stenosis. We report two cases of esophageal stenosis, the first one in a young patient with a congenital epidermolysis bullosa of Hallopeau-Siemens and the second one, in a young woman with a Pasini variant. In the first case, the esophageal stenosis was treated by careful dilation. In the second case, the endoscopy induced hemorragic bullae and septicemia, which were treated with antibiotics and total parenteral nutrition.

Adolescent↗
PubMed1994

[Carcinoid tumor with revealed by skin manifestation].

INTRODUCTION: Carcinoid tumours are often diagnosed late because a large quantity of vasoactive peptides must be accumulated to express the carcinoid syndrome. OBSERVATION: A 54-year-old male was seen for rosacea and intense episodes of vasomotor flush. The rosacea was associated with episodes of diarrhoea. The carcinoid tumour was diagnosed on the basis of raised levels of 5-hydroxyindol acetic acid. Radiology and surgery demonstrated liver, lymph node and mesenteric metastases of the primative carcinoid tumour which could not be located. Treatment combined chemotherapy (5-fluorouracil-streptozotocine) and a somatostatin analogue (octreotide). A good clinical response was obtained with a 1 year follow-up. COMMENTS: This case was discovered in misleading conditions since the rosacea overshadowed the other clinical manifestations of the carcinoid syndrome. Symptomatology resulted from the metastasic carcinoid tumour. Surgery should always be proposed. It is rarely very extensive but does allow reduction of tumour size. The role of medical treatment with a somatostatin analogue should be emphasized. This treatment can be combined with more classical chemotherapy (5-fluorouracil, streptozotocine).

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1993

Paraneoplastic pemphigoid-pemphigus? Subepidermal bullous disease with pemphigus-like direct immunofluorescence.

BACKGROUND: Paraneoplastic pemphigus is a recently described variant of pemphigus, in which classic immunologic features of pemphigus are associated with subepidermal erythema multiforme-like bullae. CASE REPORTS: Two patients with underlying malignant neoplasm had a bullous disease, which had clinical and histologic features suggestive of bullous pemphigoid while direct immunofluorescence revealed intercellular deposits of IgG and C3 throughout the malpighian layer of epidermis, a pattern usually diagnostic for pemphigus. Indirect immunofluorescence studies were negative. One mg/kg/day prednisone was enough to cure the eruption in a couple of weeks without any recurrence. CONCLUSIONS: The disease differs from the recently reported paraneoplastic pemphigus and from other bullous diseases associating circulating pemphigus-like antibodies with clinical, histologic, and often even immunologic features of bullous pemphigoid.

Aged↗
PubMed1993

[Diffuse neonatal hemangiomatosis. A case with tetralogy of Fallot].

In neonatal disseminated hemangiomatosis, multiple immature capillary hemangiomas are widely distributed in the skin, mucous membranes, and internal organs including the liver, lungs, and larynx. In patients with life-threatening visceral involvement, corticosteroids or interferon may be required. A case in a female infant with tetralogy of Fallot is reported.

Adrenal Cortex Hormones↗
PubMed1992

[Skin manifestations revealing monocytic leukemia. A case report].

A three-month-old developed a deep nodule over the elbow, then two weeks later additional nodules over the trunk with enlargement of the liver and spleen. Examination of the bone marrow established the diagnosis of monocytic leukemia. Acute monocytic leukemia is the most common leukemia in infants. Skin lesions, visible as red, brown or purple nodules ("blueberry muffin lesions") and confluent areas of purpura are common and may occur as the first manifestations of the disease. These skin lesions are not specific of leukemia and other diagnoses should be considered including histiocytosis, neuroblastoma, and skin erythropoiesis (in Torch syndrome, hemolytic disease of the newborn, hereditary spherocytosis, and twin-to-twin transfusion syndrome).

Diagnosis, Differential↗
PubMed1991

[Multiple rare tumors of the hand: a case of multifocal reticulohistiocytosis].

The authors report the case of a woman operated for multiple dorsal nodes of the fingers with a lytic appearance on X-rays of the distal joints. The histopathology concluded on multicentric reticulohistiocytosis which is a very rare disease (fewer than 100 cases) affecting the hand (90%), skin and joints, and other organ systems. The prognosis is not good as the disease is disabling to the hand and malignant diseases may occur in 15 to 25% of cases. No treatment, even very aggressive, has been shown to be truly effective.

Adult↗
PubMed1991

[Malignant melanoma of the oral mucosa].

The oral cavity is a mave "localisation" for the malignant melanoma's development. Surgical excision with a wide margin is the treatment of choice for localized oral melanoma. The prognosis is particularly poor when metastasis occurs. One case is reported, in a alveolar site.

Diagnosis, Differential↗
PubMed1989

[Papillary eccrine adenoma].

Papillary eccrine adenoma is a rare benign eccrine tumor of the skin occasionally difficult to differentiate from tubular apocrine adenoma. A new case of this eccrine lesion with immunohistochemical characterization is reported and a review of the literature emphasizing the differential features between these two entities is made.

Adenoma↗