Biomedical subjects

F Tognetti

Publications and source records attributed to F Tognetti.

60 records · Page 4Linked to original sources

PubMedDate not supplied

Cerebral ischemia and asymptomatic coronary artery disease: a prospective study of 83 patients.

A prospective cardiologic evaluation was performed in 83 consecutive patients with transient cerebral ischemia or mild stroke and without symptoms or electrocardiographic signs of ischemic heart disease. Patients were studied with an electrocardiographic exercise test; a positive test was followed by exercise Thallium-201 myocardial scintigraphy. Results were compared to those obtained in a group of 83 age and sex-matched healthy subjects submitted to the same study protocol. Asymptomatic coronary artery disease was detected in 28% of cerebrovascular patients with adequate electrocardiographic exercise test. A scintigraphic perfusion defect of variable extension was found in 19 of them. In the control group the electrocardiographic exercise test was positive in only 6% (p less than 0.01). Our results support the concept that: asymptomatic ischemic heart disease is often associated with cerebrovascular disease; therefore cerebral ischemic attacks may be a marker of coronary artery disease, an active investigation of the heart should be considered in cerebrovascular patients in order to plan optimal, comprehensive management.

Adult↗

PubMedDate not supplied

Subarachnoid hemorrhage: frequency and severity of cardiac arrhythmias. A survey of 70 cases studied in the acute phase.

The frequency and severity of cardiac arrhythmias were studied in 70 patients with spontaneous subarachnoid hemorrhage investigated prospectively with 24-hour Holter monitoring. Patients were less than 70 years old and without clinical and/or ECG signs of previous heart disease; Holter monitoring was initiated within 48 hours of subarachnoid hemorrhage. Arrhythmias were detected in 64 of the 70 patients (91%). Twenty-nine of the 70 patients (41%) showed serious cardiac arrhythmias; malignant ventricular arrhythmias, i.e., torsade de pointe and ventricular flutter or fibrillation, occurred in 3 cases. Serious ventricular arrhythmias were associated with QTc prolongation and hypokalemia. No correlation was found between the frequency and severity of cardiac arrhythmias and the neurologic condition, the site and extent of intracranial blood on computed tomography scan, or the location of ruptured malformation. The extremely high incidence of cardiac arrhythmias, sometimes serious, in the acute period after subarachnoid hemorrhage and the absence of clinical and radiologic predictors make systematic continuous ECG monitoring compulsory to improve the overall results of subarachnoid hemorrhage, irrespective of early or delayed surgical treatment.

Acute Disease↗

PubMedDate not supplied

Metastatic spread of benign intracranial meningioma.

A case of benign meningioma of the superior sagittal sinus is reported, which recurred three times during a period of six years. At the time of the first recurrence the overlying bone was eroded and the tumor grew subcutaneously; the second recurrence was associated with a pulmonary metastatic deposit of extraordinary size. The literature dealing with remote extracranial spread of meningiomas is briefly reviewed.

Humans↗

PubMedDate not supplied

Pineal germinoma with massive supratentorial extension. Case report.

An uncommon case of huge pineal germinoma without associated ventricular enlargement is presented. The tumor extended supratentorially in dumb-bell form to affect both cerebral hemispheres, simulating a glioma at neuroradiological examinations. Subtotal removal through a bilateral parieto-occipital approach plus radiation therapy were followed by relief of symptoms for over one year since surgery. The misleading patterns of the tumor and the delayed onset of symptoms in our case are outlined.

Adolescent↗

PubMedDate not supplied

Superior cerebellar artery aneurysms. Case report.

The authors report a case of left superior cerebellar artery aneurysm successfully operated. A review of the literature produced only 7 other reported cases. Symptoms and operative procedures are briefly discussed.

Adult↗

PubMedDate not supplied

[Persistence of the median artery: possible cause of the carpal tunnel syndrome].

A case of Carpal Tunnel Syndrome (S.T.S.) in a patient with Persistence of the Median Artery is reported. The Authors consider this rare-condition as a possible cause of C.T.S. The persisting vessel may cause a damage to the Median Nerve in two difeent ways: 1) Compression and 2) Ischemia. The latter pathogenesis is expecially advocated when anastomotic connection between the Median Artery and the Radial and Ulnar Arteries as well as the Superficial Palmar Arch are poor. Two different clinical pictures are possible: an acute onset, after a thrombosis, or a chronic impairment when the vessel is previous. As treatment, the Authors always recommend the decompression of the Carpal Tunnel and the dissection of the Persisting Artery; on the other side, they consider the excision of the vessel possible only when a sufficient anastomotic blood-supply is ensured.

Acute Disease↗